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GSH:GSSG ratio: biomarker evidence

GSH:GSSG ratio appears in 1 entry of the OSMF biomarker atlas, covering Gulf War Illness. Across those entries it is reduced in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Gulf War Illness

Where GSH:GSSG ratio is reported

Also listed as: Redox balance

ConditionDirectionCompared againstAssociated symptomsSource
Gulf War Illness↓ reducedhealthy Gulf War veteran controlsOxidative damageGean et al. 2021

Frequently asked questions

In which conditions is GSH:GSSG ratio altered?

In the OSMF atlas GSH:GSSG ratio is reported in Gulf War Illness. It is reduced in 1 across 1 entries.

Is there a standard clinical test for GSH:GSSG ratio?

The atlas entries for GSH:GSSG ratio do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal GSH:GSSG ratio result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). GSH:GSSG ratio across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/gsh-gssg-ratio.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.