Research Tracker›Biomarker Atlas›Marker Pages›Cartilage Oligomeric Matrix Protein (COMP)

Cartilage Oligomeric Matrix Protein (COMP): biomarker evidence

Cartilage Oligomeric Matrix Protein (COMP) appears in 1 entry of the OSMF biomarker atlas, covering Osteoarthritis. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Osteoarthritis

Where Cartilage Oligomeric Matrix Protein (COMP) is reported

ConditionDirectionCompared againstAssociated symptomsSource
Osteoarthritis↑ elevatedknee OA vs healthy controls—Bi et al. 2018

Frequently asked questions

In which conditions is Cartilage Oligomeric Matrix Protein (COMP) altered?

In the OSMF atlas Cartilage Oligomeric Matrix Protein (COMP) is reported in Osteoarthritis. It is elevated in 1 across 1 entries.

Is there a standard clinical test for Cartilage Oligomeric Matrix Protein (COMP)?

The atlas entries for Cartilage Oligomeric Matrix Protein (COMP) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Cartilage Oligomeric Matrix Protein (COMP) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Cartilage Oligomeric Matrix Protein (COMP) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/cartilage-oligomeric-matrix-protein-comp.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.