Where 6-minute walk distance is reported
Also listed as: Exercise capacity; Functional capacity
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| Gulf War Illness | ↓ reduced | healthy Gulf War veteran controls | Physical limitation | Gean et al. 2021 |
| ME/CFS | ↓ reduced | healthy controls | Activity limitation | Maksoud et al. 2023 |
| PACVS | ↓ reduced | healthy controls | Reduced functional capacity | Halma 2024 |
Frequently asked questions
In which conditions is 6-minute walk distance altered?
In the OSMF atlas 6-minute walk distance is reported in Gulf War Illness, ME/CFS, PACVS. It is reduced in 3 across 3 entries.
Does 6-minute walk distance point to one specific diagnosis?
No. Because 6-minute walk distance changes in several conditions (Gulf War Illness, ME/CFS, PACVS), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.
Is there a standard clinical test for 6-minute walk distance?
The atlas entries for 6-minute walk distance do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal 6-minute walk distance result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-06-30 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.