Research Tracker›Biomarker Atlas›Marker Pages›Cytokeratin-18 (CK-18)

Cytokeratin-18 (CK-18): biomarker evidence

Cytokeratin-18 (CK-18) appears in 1 entry of the OSMF biomarker atlas, covering NAFLD / MASH (Metabolic-Associated Steatohepatitis). Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

NAFLD / MASH (Metabolic-Associated Steatohepatitis)

Where Cytokeratin-18 (CK-18) is reported

ConditionDirectionCompared againstAssociated symptomsSource
NAFLD / MASH (Metabolic-Associated Steatohepatitis)↑ elevatedNASH vs without NASH/healthy controls—Feldstein et al. 2009

Frequently asked questions

In which conditions is Cytokeratin-18 (CK-18) altered?

In the OSMF atlas Cytokeratin-18 (CK-18) is reported in NAFLD / MASH (Metabolic-Associated Steatohepatitis). It is elevated in 1 across 1 entries.

Is there a standard clinical test for Cytokeratin-18 (CK-18)?

The atlas entries for Cytokeratin-18 (CK-18) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Cytokeratin-18 (CK-18) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Cytokeratin-18 (CK-18) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/cytokeratin-18-ck-18.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.