Peer-Reviewed Literature Synthesis

Rheumatoid Arthritis Biomarker Atlas

Molecular alterations reported in Rheumatoid Arthritis compared to healthy controls, from peer-reviewed literature.

Spontaneous remission11% achieve drug-free remission (DFR) at median 74 months; most cohorts show 10-15% DFR ceiling
Best-intervention remissionEarly aggressive treat-to-target improves DFR rates modestly; some biologic-era cohorts reach 20-25% DFR; on-drug…
Gap sizeSmall for drug-free remission (biological ceiling is genuinely low); large gap between on-drug remission and drug-free…
Primary barrierbiological (DFR); practice (on-drug remission underachieved due to treatment inertia)
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Rheumatoid Arthritis patients relative to a named comparison population — not inferred.

5
Curated markers
2
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Matuszewska et al. 2016

DOI: 10.5604/17322693.1198270 →
Peer-Reviewed Literature

Kourilovitch et al. 2014

DOI: 10.1016/j.jaut.2014.01.027 →
Peer-Reviewed Literature

Inciarte-Mundo et al. 2022

DOI: 10.3389/fimmu.2022.1001025 →
Peer-Reviewed Literature

Qin et al. 2022

DOI: 10.1136/ard-2022-222605 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

Individual Rheumatoid Arthritis biomarker pages

Each Rheumatoid Arthritis marker has its own page with direction, comparison group, symptoms, test details, citation and FAQ. Browse all marker pages.

Immune

Inflammatory

Cite this page

Reusing these data? Please cite the tracker so others can find the source.

Open Source Medicine Foundation. (2026). Rheumatoid Arthritis Biomarkers: 5 Blood Tests & Lab Markers. Research Tracker. https://research.opensourcemed.info/rheumatoid-arthritis-biomarkers.html (accessed )

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