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β2-adrenergic receptor autoantibodies across conditions

β2-adrenergic receptor autoantibodies appears in 2 entries of the OSMF biomarker atlas, covering Gulf War Illness, ME/CFS. Across those entries it is elevated in 2. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Gulf War IllnessME/CFS

Where β2-adrenergic receptor autoantibodies is reported

Also listed as: Anti-β2AR; GPCR autoAbs — ME/CFS overlap

ConditionDirectionCompared againstAssociated symptomsSource
Gulf War Illness↑ elevatedhealthy Gulf War veteran controlsDysautonomiaGean et al. 2021
ME/CFS↑ elevatedhealthy controlsDysautonomia, POTSMaksoud et al. 2023

Frequently asked questions

In which conditions is β2-adrenergic receptor autoantibodies altered?

In the OSMF atlas β2-adrenergic receptor autoantibodies is reported in Gulf War Illness, ME/CFS. It is elevated in 2 across 2 entries.

Does β2-adrenergic receptor autoantibodies point to one specific diagnosis?

No. Because β2-adrenergic receptor autoantibodies changes in several conditions (Gulf War Illness, ME/CFS), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

Is there a standard clinical test for β2-adrenergic receptor autoantibodies?

The atlas entries for β2-adrenergic receptor autoantibodies do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal β2-adrenergic receptor autoantibodies result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). β2-adrenergic receptor autoantibodies across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/beta2-adrenergic-receptor-autoantibodies.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.