Histidine: biomarker evidence

Histidine appears in 1 entry of the OSMF biomarker atlas, covering Long COVID. Across those entries it is reduced in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Long COVID

Where Histidine is reported

Also listed as: Amino acid

ConditionDirectionCompared againstAssociated symptomsSource
Long COVID↓ reducedrecovered individuals without persistent symptomsAmino acid metabolismSaito et al. 2024

Frequently asked questions

In which conditions is Histidine altered?

In the OSMF atlas Histidine is reported in Long COVID. It is reduced in 1 across 1 entries.

Is there a standard clinical test for Histidine?

The atlas entries for Histidine do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Histidine result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Histidine across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/histidine.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.