Where LF/HF ratio is reported
Also listed as: Sympathovagal balance
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| ME/CFS | ↕ inconsistent | healthy controls | Autonomic imbalance | Nelson et al. 2019 |
Frequently asked questions
In which conditions is LF/HF ratio altered?
In the OSMF atlas LF/HF ratio is reported in ME/CFS. It is mixed in 1 across 1 entries.
Is there a standard clinical test for LF/HF ratio?
The atlas entries for LF/HF ratio do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal LF/HF ratio result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.