Research Tracker›Biomarker Atlas›Marker Pages›T cell exhaustion markers

T cell exhaustion markers: biomarker evidence

T cell exhaustion markers appears in 1 entry of the OSMF biomarker atlas, covering Long COVID. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Long COVID

Where T cell exhaustion markers is reported

Also listed as: PD-1, TIM-3, LAG-3

ConditionDirectionCompared againstAssociated symptomsSource
Long COVID↑ elevatedhealthy controlsT cell dysfunctionBaalbaki et al. 2025

Frequently asked questions

In which conditions is T cell exhaustion markers altered?

In the OSMF atlas T cell exhaustion markers is reported in Long COVID. It is elevated in 1 across 1 entries.

Is there a standard clinical test for T cell exhaustion markers?

The atlas entries for T cell exhaustion markers do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal T cell exhaustion markers result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). T cell exhaustion markers across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/t-cell-exhaustion-markers.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.