Summary
| Direction in PACVS | ↓ Reduced — lower than in the comparison group |
|---|---|
| Category | Functional |
| Also described as | Post-acute COVID quality of life |
| Compared against | HC (healthy controls) |
| Associated symptoms | Reduced quality of life |
| Test type | Clinical or physiological test |
| Source | Halma 2024 — doi:10.2196/preprints.70342 |
| Condition atlas | PACVS Biomarker Atlas |
Related Functional markers in PACVS
- Chester Step Test (VO₂ proxy) ↓
- Neurofilament light chain (NfL) ↑
- Exertional SpO₂ nadir ↓
- 6-minute walk distance ↓
- Orthostatic heart rate increment ↑
- Salivary nitric oxide ↓
- Heart rate variability (HRV) ↓
Full list: PACVS Biomarker Atlas.
Frequently asked questions
Is PAC-19QoL score high or low in PACVS?
Reduced. Studies summarised in the OSMF atlas report lower PAC-19QoL score in PACVS than in healthy controls. Source: Halma 2024.
What symptoms is PAC-19QoL score associated with in PACVS?
The cited literature associates this marker with Reduced quality of life. These are population-level associations and do not mean the marker causes the symptoms.
Which test measures PAC-19QoL score?
It is measured as a clinical or physiological test. Many of the cited studies used research-grade assays, so clinical availability may vary.
Is one abnormal PAC-19QoL score result diagnostic of PACVS?
No. No single biomarker is diagnostic of PACVS. PAC-19QoL score findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-06-30 · Page generated from pacvs.json · Browse: PACVS atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.