Summary
| Direction in Migraine | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Other |
| Compared against | healthy controls (implied by 'migraine patients') |
| Associated symptoms | migraine |
| Source | D'Andrea et al. 2010 — doi:10.1007/s10072-010-0267-8 |
| Condition atlas | Migraine Biomarker Atlas |
Related Other markers in Migraine
- 25-Hydroxyvitamin D ↓
- Homocysteine ↑
- Interleukin-6 ↑
- Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38) ↕
- Serotonin ↓
- Serum Ferritin ↓
Full list: Migraine Biomarker Atlas.
Frequently asked questions
Is Glutamate high or low in Migraine?
Elevated. Studies summarised in the OSMF atlas report higher Glutamate in Migraine than in healthy controls (implied by 'migraine patients'). Source: D'Andrea et al. 2010.
What symptoms is Glutamate associated with in Migraine?
The cited literature associates this marker with migraine. These are population-level associations and do not mean the marker causes the symptoms.
Which test measures Glutamate?
The atlas record does not list a standardised clinical test code (LOINC) for Glutamate, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.
Is one abnormal Glutamate result diagnostic of Migraine?
No. No single biomarker is diagnostic of Migraine. Glutamate findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-10-08 · Page generated from migraine.json · Browse: Migraine atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.