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CSF protein elevation: biomarker evidence

CSF protein elevation appears in 1 entry of the OSMF biomarker atlas, covering Lyme Disease. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Lyme Disease

Where CSF protein elevation is reported

Also listed as: Blood-CSF barrier dysfunction

ConditionDirectionCompared againstAssociated symptomsSource
Lyme Disease↑ elevatedNormal CSFNeuroborreliosis, meningitisLantos et al. 2021

Frequently asked questions

In which conditions is CSF protein elevation altered?

In the OSMF atlas CSF protein elevation is reported in Lyme Disease. It is elevated in 1 across 1 entries.

What is the LOINC code for CSF protein elevation?

Entries in this atlas use LOINC 2880-3. LOINC codes identify the laboratory observation so results can be compared across systems.

Is one abnormal CSF protein elevation result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). CSF protein elevation across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/csf-protein-elevation.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.