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Réunion chikungunya viremic inception cohort (Schilte)
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Design notes & limitations. Inception cohort defined by acute RT-PCR viraemia (not just serology), with banked acute-phase specimens and 3-year follow-up of chronic arthralgia. A rarer, stronger complement to the serology-ascertained TELECHIK cohort on the same outbreak.
Identity & trigger
- Cohort id
schilte-2013-chikungunya-reunion- Aliases
- Réunion 2006 chikungunya 36-month cohort
- Outbreak / event
- Réunion chikungunya outbreak 2005-06
- Pathogen
- Chikungunya virus (Virus)
- Exposure ascertainment
- pcr
Design
- Design
- Prospective (inception)
- Denominator defined
- Partial
- Denominator method
- Patients with RT-PCR-confirmed acute chikungunya viraemia during the 2006 Réunion outbreak, enrolled at the acute phase and followed for 3 years.
- Recruitment
- outpatient clinic
- Time zero
- RT-PCR-confirmed acute chikungunya viraemia (month)
- Control group
- None
Size & attrition
- Enrolled
- 180
- Analysed / enrolled
- 180/180 (100%)
- Max follow-up (months)
- 36
Biospecimens
- Specimens
- Yes
- Types
- serum, plasma
- Acute-phase specimens
- Yes
- Biobank
- Unknown
- External access
- Unknown
Observations (1)
Symptoms
60% Proportion
- Measure
- Arthralgia / rheumatic musculoskeletal pain sym:arthralgia
- As worded
- “experienced chikungunya-associated arthralgia during the 3-year follow-up”
- Population
- whole cohort · denominator Assessed at timepoint · N=n=180
- Timing
- 36 mo (24 mo+) · ref Not reported
- Method
- Unclear · Structured symptom questionnaire (author-defined)
- Comparator
- no comparator
- Comparability signature
- 01a250d680 — measure sym:arthralgia · Unclear · ref Not reported · denom Assessed at timepoint · 24 mo+ · Proportion
- Provenance
- Abstract (about 60% experienced arthralgia over 3 years) · Manual · verified OSMF research-tracker (web-verified against source) on 2026-07-20
Publications
- Schilte C, Staikowsky F, Couderc T, et al. (2013). Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study. PLoS Neglected Tropical Diseases. PMID 23556021 · DOI 10.1371/journal.pntd.0002137 primary
Provenance & verification
- Registration
- n/r
- Funders
- Institut Pasteur, INSERM
- Related cohorts
- telechik-reunion (Sibling analysis), marimoutou-2012-gendarmes (Sibling analysis)
- Symptom-inventory scope
- Targeted panel
- Last verified
- 2026-07-20 — OSMF research-tracker (web-verified against source)