Disease × agent pairs

Irritable Bowel Syndrome (IBS): candidate agents with evidence

8 agents linked to Irritable Bowel Syndrome by at least one registered trial or two publications, ranked by the OSMF evidence score. Not treatment advice.

Research Tracker › Pairs › Irritable Bowel Syndrome (IBS)
Open Irritable Bowel Syndrome (IBS) in the Repurposing ExplorerIrritable Bowel Syndrome (IBS) hub

Caffeine

Drug · tier A · 8 trials (0 recruiting) · 6 publications · score 57.0

Pregabalin

Drug · tier A · 3 trials (1 recruiting) · 8 publications · score 53.0

Gabapentin

Drug · tier A · 1 trials (0 recruiting) · 9 publications · score 52.5

Imipramine

Drug · tier A · 0 trials (0 recruiting) · 6 publications · score 35.0

Ethosuximide

Drug · tier A · 2 trials (1 recruiting) · 3 publications · score 34.5

Pentoxifylline

Drug · tier A · 2 trials (1 recruiting) · 1 publications · score 30.0

Verapamil

Drug · tier A · 1 trials (0 recruiting) · 0 publications · score 24.5

Gabapentin Enacarbil

Drug · tier A · 1 trials (0 recruiting) · 0 publications · score 22.5

Research map, not treatment advice. Built 2026-10-07.