Drug repurposing research map

Disease × agent evidence pages

1416 pages, one per condition-agent pair with at least one registered trial or two publications, across 96 conditions. Each page lists trials with NCT links, literature with PubMed links, an evidence tier and a transparent score.

Research Tracker › Pairs

Research map, not treatment advice. These pages summarise what has been studied, not what works.

Open the interactive Repurposing Explorer Agent hub pages

Post-Viral & Complex Chronic Illness

Gulf War Illness

3 agent pages · 0 trials · 9 publications

Long COVID

411 agent pages · 457 trials · 2548 publications

Lyme / PTLDS

4 agent pages · 0 trials · 20 publications

ME/CFS

191 agent pages · 209 trials · 549 publications

Other post-viral syndromes

5 agent pages · 0 trials · 25 publications

PACVS

1 agent pages · 0 trials · 8 publications

POTS

4 agent pages · 0 trials · 22 publications

Autoimmune & Rheumatologic

Rheumatoid Arthritis

25 agent pages · 159 trials · 276 publications

Cardiometabolic & Renal

Atrial Fibrillation

15 agent pages · 51 trials · 104 publications

Chronic Kidney Disease

21 agent pages · 131 trials · 154 publications

Type 2 Diabetes

24 agent pages · 190 trials · 256 publications

Chronic disease (RepurpOS)

ADHD

9 agent pages · 37 trials · 69 publications

Age-Related Macular Degeneration (AMD)

3 agent pages · 5 trials · 7 publications

Alcohol Use Disorder

4 agent pages · 19 trials · 23 publications

Alpha-1 Antitrypsin Deficiency (AATD)

1 agent pages · 0 trials · 2 publications

Alzheimer's Disease and Other Dementias

11 agent pages · 0 trials · 76 publications

Amyotrophic Lateral Sclerosis (ALS)

4 agent pages · 7 trials · 2 publications

Ankylosing Spondylitis / Axial Spondyloarthropathy

16 agent pages · 79 trials · 122 publications

Anxiety Disorders

12 agent pages · 68 trials · 61 publications

Atopic Dermatitis (Eczema)

7 agent pages · 34 trials · 1 publications

Benign Prostatic Hyperplasia (BPH)

1 agent pages · 8 trials · 8 publications

Beta Thalassemia

5 agent pages · 25 trials · 6 publications

Bipolar Disorder

8 agent pages · 37 trials · 54 publications

Bladder Cancer

2 agent pages · 16 trials · 0 publications

Breast Cancer

23 agent pages · 148 trials · 209 publications

Cancer

22 agent pages · 171 trials · 307 publications

Carpal Tunnel Syndrome

3 agent pages · 18 trials · 7 publications

Cervical Cancer

7 agent pages · 44 trials · 20 publications

Chronic Lymphocytic Leukaemia (CLL)

5 agent pages · 25 trials · 0 publications

Chronic Pancreatitis

2 agent pages · 9 trials · 3 publications

Coeliac Disease (Refractory / RCD)

2 agent pages · 9 trials · 0 publications

Colorectal Cancer

22 agent pages · 144 trials · 146 publications

COPD

22 agent pages · 140 trials · 172 publications

Cystic Fibrosis

6 agent pages · 20 trials · 22 publications

Fibromyalgia

1 agent pages · 1 trials · 1 publications

GERD (Gastroesophageal Reflux Disease)

3 agent pages · 3 trials · 6 publications

Glaucoma

13 agent pages · 23 trials · 66 publications

Gout

4 agent pages · 11 trials · 18 publications

Haemophilia A / B

4 agent pages · 32 trials · 18 publications

Heart Failure

16 agent pages · 80 trials · 105 publications

Hepatitis B

2 agent pages · 9 trials · 9 publications

HIV/AIDS

25 agent pages · 200 trials · 269 publications

Hypertension

22 agent pages · 119 trials · 206 publications

Immune Thrombocytopaenia (ITP)

4 agent pages · 9 trials · 0 publications

Inflammatory Bowel Disease (Crohn's / UC)

17 agent pages · 80 trials · 146 publications

Inflammatory Myopathies (Dermatomyositis / PM / IBM)

5 agent pages · 15 trials · 17 publications

Insomnia / Sleep Disorders

20 agent pages · 97 trials · 182 publications

Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

2 agent pages · 2 trials · 0 publications

Irritable Bowel Syndrome (IBS)

8 agent pages · 18 trials · 33 publications

Kidney Stones (Nephrolithiasis)

1 agent pages · 1 trials · 0 publications

Long COVID / Post-Acute COVID Sequelae (PACVS)

12 agent pages · 2 trials · 102 publications

Lung Cancer

22 agent pages · 138 trials · 173 publications

Lupus Nephritis

6 agent pages · 17 trials · 10 publications

ME/CFS (Myalgic Encephalomyelitis / Chronic Fatigue Syndrome)

1 agent pages · 2 trials · 0 publications

Measles

2 agent pages · 0 trials · 10 publications

Melanoma

4 agent pages · 14 trials · 9 publications

Migraine

4 agent pages · 7 trials · 0 publications

Multiple Myeloma

9 agent pages · 67 trials · 2 publications

Myasthenia Gravis (MG)

6 agent pages · 12 trials · 10 publications

Myelodysplastic Syndromes (MDS)

10 agent pages · 73 trials · 35 publications

NAFLD / MASH (Metabolic-Associated Steatohepatitis)

8 agent pages · 5 trials · 38 publications

Non-Hodgkin Lymphoma (NHL)

8 agent pages · 50 trials · 14 publications

Obesity

18 agent pages · 89 trials · 140 publications

Obstructive Sleep Apnoea (OSA)

6 agent pages · 19 trials · 4 publications

Opioid Use Disorder

12 agent pages · 59 trials · 66 publications

Osteoporosis

6 agent pages · 32 trials · 39 publications

Ovarian Cancer

5 agent pages · 27 trials · 25 publications

Parkinson's Disease

8 agent pages · 25 trials · 11 publications

PCOS (Polycystic Ovary Syndrome)

2 agent pages · 10 trials · 6 publications

Peripheral Artery Disease (PAD)

8 agent pages · 34 trials · 38 publications

Peripheral Neuropathy (Diabetic Peripheral Neuropathy)

6 agent pages · 27 trials · 31 publications

Polycystic Kidney Disease (ADPKD)

4 agent pages · 7 trials · 10 publications

Primary Sclerosing Cholangitis (PSC)

6 agent pages · 3 trials · 7 publications

Prostate Cancer

7 agent pages · 30 trials · 40 publications

Psoriasis (Nail / Palmoplantar)

3 agent pages · 4 trials · 2 publications

Psoriatic Arthritis

3 agent pages · 12 trials · 21 publications

Pulmonary Arterial Hypertension (PAH)

2 agent pages · 8 trials · 1 publications

Restless Legs Syndrome (RLS)

1 agent pages · 1 trials · 0 publications

Sarcopenia

7 agent pages · 32 trials · 11 publications

Schizophrenia

14 agent pages · 51 trials · 108 publications

Sepsis

9 agent pages · 38 trials · 61 publications

Sickle Cell Disease

5 agent pages · 33 trials · 6 publications

Stroke (Ischaemic / Cerebrovascular Disease)

12 agent pages · 64 trials · 102 publications

Systemic Lupus Erythematosus (SLE)

4 agent pages · 17 trials · 11 publications

Thyroid Cancer (Well-Differentiated)

5 agent pages · 25 trials · 2 publications

Tinnitus

3 agent pages · 0 trials · 19 publications

Vitiligo

7 agent pages · 35 trials · 40 publications

Endocrine & Metabolic

Hypothyroidism

7 agent pages · 27 trials · 34 publications

Type 1 Diabetes

9 agent pages · 59 trials · 19 publications

Gastrointestinal & Hepatic

Hepatitis C

13 agent pages · 64 trials · 98 publications

Mental Health

Major Depressive Disorder

25 agent pages · 169 trials · 181 publications

Musculoskeletal & Pain

Low Back Pain

7 agent pages · 17 trials · 34 publications

Osteoarthritis

7 agent pages · 25 trials · 50 publications

Neurological

Epilepsy

11 agent pages · 33 trials · 65 publications

Multiple Sclerosis

10 agent pages · 38 trials · 48 publications

Respiratory

Asthma

24 agent pages · 141 trials · 207 publications

Built 2026-10-07. Data from ClinicalTrials.gov, PubMed, Open Targets, ChEMBL, DGIdb and the OSMF therapeutic agent database.