Trials by therapeutic agent

Losartan clinical trials

2 post-viral trials on ClinicalTrials.gov · updated October 2026

Last updated 07 October 2026 from ClinicalTrials.gov. Trial statuses are refreshed automatically; check the registry record for the latest status and contact details.

2 trials0 open to enrolment1 active, not recruiting1 completed

All interventional trials in our ClinicalTrials.gov extract that list Losartan as an intervention, across Long COVID / PASC (1), Unspecified / Overlap (1). 0 are currently open to enrolment and 1 has completed. Read the OSMF evidence profile for Losartan for literature, mechanism and dosing context.

Intervention names are normalised from the registry's own arm labels, so the same compound can appear under a brand name, a generic name or a combination; check the full agent index for related entries.

⚠️
Not medical advice. This page is an automatically compiled index of entries on ClinicalTrials.gov. Listing here is not an endorsement of any trial, sponsor or treatment, and trial status can change between our refreshes. Always confirm details on ClinicalTrials.gov and discuss participation with your own clinician.

Active, not recruiting (1)

Active, not recruitingPhase 3 NCT05619653
Sponsor: Valentina Puentmann (Academic / non-profit / other)
Intervention(s): Prednisolone, Losartan
Condition group: Long COVID / PASC
Start: Dec 2022  |  Primary completion: Aug 2025  |  Enrollment: 279 (actual)
Record last updated: Dec 2025

Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.

View on ClinicalTrials.gov ↗

Completed (1)

CompletedEarly Phase 1 NCT01210430
Sponsor: New York Medical College (Academic / non-profit / other)
Intervention(s): Losartan, Ascorbic Acid, Normal Saline
Condition group: Unspecified / Overlap
Start: Jul 2010  |  Primary completion: Jun 2015  |  Enrollment: 74 (actual)
Record last updated: Jun 2021

The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of POTS in individual patients. Specific causes for POTS may vary from patient to patient. Patients will be compared to healthy control subjects.

View on ClinicalTrials.gov ↗

Frequently asked questions

How do I join a clinical trial?

Open the trial's ClinicalTrials.gov record (the "View on ClinicalTrials.gov" button), read the Eligibility Criteria and Contacts and Locations sections, and contact the study team listed there. Trials only enrol at the sites shown in the record, so check whether a site is near you or whether the study is remote/decentralised. Your own clinician can help you judge whether a trial is a sensible option and may need to provide medical records.

What do the trial phases mean?

Early Phase 1 / Phase 1 studies test safety and dosing in a small group. Phase 2 studies look for a signal of benefit in a larger group and keep checking safety. Phase 3 studies are large confirmatory trials designed to show whether a treatment works well enough for approval. Phase 4 studies follow approved treatments after they reach the market. "Phase not applicable" is used by the registry for behavioural, device, rehabilitation and other non-drug interventions.

Does the Open Source Medicine Foundation run these trials?

No. OSMF does not sponsor, run or recruit for any trial on this page. We compile public registry entries from ClinicalTrials.gov so patients and clinicians can find them in one place. For questions about a specific study, contact the sponsor or study team listed on its ClinicalTrials.gov record.

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Cite this page
Open Source Medicine Foundation. Losartan clinical trials for Long COVID, ME/CFS and post-viral illness (2 trials, updated October 2026). Research Tracker, 07 October 2026. https://research.opensourcemed.info/trials/by-agent/losartan.html
Underlying dataset (JSON, CC BY 4.0): https://research.opensourcemed.info/data/clinical_trials/clinical_trials_current.json. Source records: ClinicalTrials.gov.

Related: all agents · recruiting Long COVID trials · recruiting ME/CFS trials · open in trial finder.