Trials by therapeutic agent

Cognitive Rehabilitation clinical trials

2 post-viral trials on ClinicalTrials.gov · updated October 2026

Last updated 07 October 2026 from ClinicalTrials.gov. Trial statuses are refreshed automatically; check the registry record for the latest status and contact details.

2 trials0 open to enrolment1 completed1 unknown status

All interventional trials in our ClinicalTrials.gov extract that list Cognitive Rehabilitation as an intervention, across Long COVID / PASC (2). 0 are currently open to enrolment and 1 has completed. Read the OSMF evidence profile for Cognitive Rehabilitation for literature, mechanism and dosing context.

Intervention names are normalised from the registry's own arm labels, so the same compound can appear under a brand name, a generic name or a combination; check the full agent index for related entries.

⚠️
Not medical advice. This page is an automatically compiled index of entries on ClinicalTrials.gov. Listing here is not an endorsement of any trial, sponsor or treatment, and trial status can change between our refreshes. Always confirm details on ClinicalTrials.gov and discuss participation with your own clinician.

Completed (1)

CompletedPhase not applicable NCT05676047
Sponsor: McMaster University (Academic / non-profit / other)
Intervention(s): Cognitive Rehabilitation
Condition group: Long COVID / PASC
Start: May 2023  |  Primary completion: Jan 2025  |  Enrollment: 100 (actual)
Record last updated: Jan 2025

The investigators are comparing two different methods for helping adults with Long Coronavirus (COVID) also known as Post-Coronavirus Syndrome or Post-Coronavirus Condition manage everyday cognitive challenges. Cognitive rehabilitation is a type of therapy that helps people who have challenges with everyday thinking because of a brain injury.

View on ClinicalTrials.gov ↗

Unknown status (1)

Unknown statusPhase not applicable NCT05731570
Sponsor: University College, London (Academic / non-profit / other)
Intervention(s): Cognitive Rehabilitation
Condition group: Long COVID / PASC
Start: Feb 2023  |  Primary completion: Jul 2024  |  Enrollment: 78 (actual)
Record last updated: Jun 2024

Cognitive impairment is increasingly recognised as a major component of long Covid, and is estimated to be present in 25-75% of affected individuals. This impairment impacts quality of life and the loss of functional ability has major consequences for affected people, their families and the wider economy given people's difficulty in returning to work.

View on ClinicalTrials.gov ↗

Frequently asked questions

How do I join a clinical trial?

Open the trial's ClinicalTrials.gov record (the "View on ClinicalTrials.gov" button), read the Eligibility Criteria and Contacts and Locations sections, and contact the study team listed there. Trials only enrol at the sites shown in the record, so check whether a site is near you or whether the study is remote/decentralised. Your own clinician can help you judge whether a trial is a sensible option and may need to provide medical records.

What do the trial phases mean?

Early Phase 1 / Phase 1 studies test safety and dosing in a small group. Phase 2 studies look for a signal of benefit in a larger group and keep checking safety. Phase 3 studies are large confirmatory trials designed to show whether a treatment works well enough for approval. Phase 4 studies follow approved treatments after they reach the market. "Phase not applicable" is used by the registry for behavioural, device, rehabilitation and other non-drug interventions.

Does the Open Source Medicine Foundation run these trials?

No. OSMF does not sponsor, run or recruit for any trial on this page. We compile public registry entries from ClinicalTrials.gov so patients and clinicians can find them in one place. For questions about a specific study, contact the sponsor or study team listed on its ClinicalTrials.gov record.

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Cite this page
Open Source Medicine Foundation. Cognitive Rehabilitation clinical trials for Long COVID, ME/CFS and post-viral illness (2 trials, updated October 2026). Research Tracker, 07 October 2026. https://research.opensourcemed.info/trials/by-agent/cognitive-rehabilitation.html
Underlying dataset (JSON, CC BY 4.0): https://research.opensourcemed.info/data/clinical_trials/clinical_trials_current.json. Source records: ClinicalTrials.gov.

Related: all agents · recruiting Long COVID trials · recruiting ME/CFS trials · open in trial finder.