Trials by therapeutic agent

Active Tdcs clinical trials

2 post-viral trials on ClinicalTrials.gov · updated October 2026

Last updated 07 October 2026 from ClinicalTrials.gov. Trial statuses are refreshed automatically; check the registry record for the latest status and contact details.

2 trials0 open to enrolment1 active, not recruiting1 withdrawn

All interventional trials in our ClinicalTrials.gov extract that list Active Tdcs as an intervention, across Long COVID / PASC (2). 0 are currently open to enrolment and 0 have completed. Read the OSMF evidence profile for Active Tdcs for literature, mechanism and dosing context.

Intervention names are normalised from the registry's own arm labels, so the same compound can appear under a brand name, a generic name or a combination; check the full agent index for related entries.

⚠️
Not medical advice. This page is an automatically compiled index of entries on ClinicalTrials.gov. Listing here is not an endorsement of any trial, sponsor or treatment, and trial status can change between our refreshes. Always confirm details on ClinicalTrials.gov and discuss participation with your own clinician.

Active, not recruiting (1)

Active, not recruitingPhase not applicable NCT05092516
Sponsor: Massachusetts General Hospital (Academic / non-profit / other)
Intervention(s): Active Tdcs
Condition group: Long COVID / PASC
Start: Jun 2022  |  Primary completion: Mar 2025  |  Enrollment: 31 (actual)
Record last updated: Jul 2026

The main goal of this study is to improve dysexecutive symptoms (e.g., sustained attention, processing speed) in patients exhibiting post-acute sequelae of COVID-19 (PASC) through home-based transcranial direct current stimulation (tDCS), a noninvasive method that uses low intensity electric currents delivered to the brain through stimulation electrodes on the scalp.

View on ClinicalTrials.gov ↗

Withdrawn (1)

WithdrawnPhase not applicable NCT05589272
Sponsor: University of Minnesota (Academic / non-profit / other)
Intervention(s): Active Tdcs
Condition group: Long COVID / PASC
Start: Feb 2023  |  Primary completion: Sep 2023
Record last updated: Mar 2023

The overarching goals of this study are to employ cognitive testing to understand how transcranial direct current stimulation (tDCS), when used concurrently with cognitive training tasks, can affect cognitive impairment symptoms in individuals with long COVID, or post-acute sequelae SARS-CoV-2 infection (PASC), and to examine variability in response between active and sham tDCS treatment groups.

View on ClinicalTrials.gov ↗

Frequently asked questions

How do I join a clinical trial?

Open the trial's ClinicalTrials.gov record (the "View on ClinicalTrials.gov" button), read the Eligibility Criteria and Contacts and Locations sections, and contact the study team listed there. Trials only enrol at the sites shown in the record, so check whether a site is near you or whether the study is remote/decentralised. Your own clinician can help you judge whether a trial is a sensible option and may need to provide medical records.

What do the trial phases mean?

Early Phase 1 / Phase 1 studies test safety and dosing in a small group. Phase 2 studies look for a signal of benefit in a larger group and keep checking safety. Phase 3 studies are large confirmatory trials designed to show whether a treatment works well enough for approval. Phase 4 studies follow approved treatments after they reach the market. "Phase not applicable" is used by the registry for behavioural, device, rehabilitation and other non-drug interventions.

Does the Open Source Medicine Foundation run these trials?

No. OSMF does not sponsor, run or recruit for any trial on this page. We compile public registry entries from ClinicalTrials.gov so patients and clinicians can find them in one place. For questions about a specific study, contact the sponsor or study team listed on its ClinicalTrials.gov record.

Get new recruiting trials in your inbox.

We summarise newly registered post-viral trials and notable results on the OSMF Substack.

Subscribe on Substack
Cite this page
Open Source Medicine Foundation. Active Tdcs clinical trials for Long COVID, ME/CFS and post-viral illness (2 trials, updated October 2026). Research Tracker, 07 October 2026. https://research.opensourcemed.info/trials/by-agent/active-tdcs.html
Underlying dataset (JSON, CC BY 4.0): https://research.opensourcemed.info/data/clinical_trials/clinical_trials_current.json. Source records: ClinicalTrials.gov.

Related: all agents · recruiting Long COVID trials · recruiting ME/CFS trials · open in trial finder.