SARS-CoV-1

Virus · respiratory · 2 cohorts · 3 observations · CC BY 4.0

All PAIS cohorts in this database triggered by SARS-CoV-1. Flags mark evidentiary caveats (preprint, grey literature, patient-reported, uncontrolled, etc.).

Hong Kong SARS survivors 4-year follow-up (Lam)

Cross-sectional · N=181 · control None · 2 obs · max follow-up 48 mo

Measures: Chronic fatigue syndrome / ME-CFS caseness, Fatigue

Cross-sectional 4-year follow-up of the 2003 SARS-CoV-1 survivors, showing high rates of chronic fatigue and a subset meeting CFS criteria years after the acute illness. A single-timepoint survivor survey with no acute-phase or unexposed comparison, but historically important as a coronavirus antecedent to Long COVID.

Toronto Chronic Post-SARS Cohort (Moldofsky)

Case-control · N=29 · control Healthy convenience · 1 obs · max follow-up 36 mo

Measures: Fatigue

Deliberately included as a methodologically weak but historically important study: small (22 cases, 7 controls), cross-sectional case-control with a convenience control group, but the first to characterize an ME/CFS/fibromyalgia-like chronic syndrome after a coronavirus — an early precedent for Long COVID.