Summary
Acupuncture And Tcm-Based Lifestyle Management is tracked by OSMF as an investigational option for Long COVID; no regulator has approved it for this indication, and most post-viral conditions have no approved disease-modifying therapy at all. ClinicalTrials.gov lists 1 registered trial linking Acupuncture And Tcm-Based Lifestyle Management to Long COVID: 1 is terminated, withdrawn, suspended or of unknown status. None of the registered studies carries a drug-development phase label, which is typical for behavioural, device and supplement protocols. It plans or enrolled 100 participants. Registered activity dates to 2023. The literature layer holds 13 publications for this pair: 1 systematic review and 12 other publications. Because at least one synthesis-level source exists (systematic review, meta-analysis or Cochrane review), this pair has been assessed beyond single studies, although the synthesis may concern a different indication.
Long COVID / PASC is tracked on the OSMF post-viral programme alongside ME/CFS, Long COVID, POTS and MCAS. Across the programme, 423 candidate agents are logged for Long COVID, most of them preliminary; this page isolates the record for one of them.
Evidence table
| Evidence tier | C · Preliminary |
|---|---|
| Evidence score | 21.0 (trials 1.0, literature 15.0, tier 5, approved bonus 0.0) |
| Registered trials | 1 total: 0 recruiting, 0 active / not yet recruiting, 0 completed, 1 other |
| Linked publications | 13 (12 other publications, 1 systematic review) |
| Agent type | Behavioural (Behavioral / Protocol / Exercise) |
| Development stage (any indication) | Investigational |
| Mechanism / class | Not recorded |
| Data sources | OSMF therapeutic agent database, ClinicalTrials.gov, PubMed |
How the evidence score is calculated
- Each registered trial scores by status (recruiting / active / enrolling 3, completed 2.5, not yet recruiting 2, unknown 1, terminated / withdrawn / suspended 0.5) plus a phase bonus (phase 3-4 +2, phase 2 +1, phase 1 +0.5). The trial component is capped at 30.
- Each literature item scores by design (Cochrane review 5, meta-analysis 4, systematic review 3, RCT 3, clinical trial publication 2, curated reference 1.5, other PubMed record 1). The literature component is capped at 30.
- The existing evidence tier adds 15 (A / Strong), 10 (B / Moderate), 5 (C / Preliminary) or 0 (D / Anecdotal).
- Agents approved for any indication (max clinical phase 4) add 5, because an approved agent has an established safety profile that lowers the barrier to repurposing trials.
- The score ranks what has been studied, not what works. It does not read effect sizes or directions of effect.
Registered clinical trials
| NCT ID | Title | Status | Phase | Enrolment |
|---|---|---|---|---|
| NCT06042777 | Non-pharmacological and TCM-based Treatment for Long COVID Symptoms The Hong Kong Polytechnic University · 2023 | status unknown | Not applicable | 100 |
Published literature
- Review (PubMed validation search) PubMed record PMID 41848128
- Review (PubMed validation search) PubMed record PMID 38831890
- Review (PubMed validation search) PubMed record PMID 38576710
- Review (PubMed validation search) PubMed record PMID 37574205
- Review (PubMed validation search) PubMed record PMID 37419539
- Review (PubMed validation search) PubMed record PMID 37363406
- Review (PubMed validation search) PubMed record PMID 36505013
- Review (PubMed validation search) PubMed record PMID 36315834
- Case series (PubMed validation search) PubMed record PMID 38033774
- Case report (PubMed validation search) PubMed record PMID 40703255
- Case report (PubMed validation search) PubMed record PMID 39093769
- Case report (PubMed validation search) PubMed record PMID 35832108
- Systematic review (PubMed validation search) PubMed record PMID 39099786
Mechanism and notes
This is a behavioural, rehabilitation or protocol-based intervention rather than a molecule, so no pharmacological mechanism is recorded.
Clinical notes: Investigational for listed conditions. 1 associated trial(s) and 0 study reference(s) in current data. Review primary sources and consult specialists before use.
Safety: Limited specific safety data in these populations. Review full prescribing information and consult specialist. Many agents used off-label or investigational.
Dosing in studies: See linked studies/trials for reported doses and durations; typical protocols vary widely.
Frequently asked questions
Is Acupuncture And Tcm-Based Lifestyle Management approved for Long COVID?
Acupuncture And Tcm-Based Lifestyle Management is tracked by OSMF as an investigational option for Long COVID; no regulator has approved it for this indication, and most post-viral conditions have no approved disease-modifying therapy at all. Approval status for the specific indication should always be confirmed with the relevant regulator and prescribing information.
Is Acupuncture And Tcm-Based Lifestyle Management in clinical trials for Long COVID?
ClinicalTrials.gov lists 1 registered trial linking Acupuncture And Tcm-Based Lifestyle Management to Long COVID: 1 is terminated, withdrawn, suspended or of unknown status. None of the registered studies carries a drug-development phase label, which is typical for behavioural, device and supplement protocols. It plans or enrolled 100 participants. Registered activity dates to 2023.
What does the evidence show for Acupuncture And Tcm-Based Lifestyle Management in Long COVID?
Trials of Acupuncture And Tcm-Based Lifestyle Management in Long COVID are registered but none has completed, so there is no outcome evidence from those studies yet; the record is a signal of research interest. OSMF's existing evidence tier for this pair is C (Preliminary), taken from the OSMF therapeutic agent database, which grades agents by the volume and design of condition-specific evidence rather than by effect size.
Cite this page
Data: ClinicalTrials.gov, PubMed, Open Targets, ChEMBL, DGIdb and the OSMF therapeutic agent database. Last updated 2026-10-07. Page built 2026-10-07.