autoimmune gastritis — RepurpOS

Disease overview

Alterations

100

Molecular (A)

100

Clinical (B–E)

Direct drugs

Via biomarker

109

Natural agents

Natural products

Merged ranked

109

With trial/literature evidence

Sources: Open Targets, DGIdb, ChEMBL, ClinicalTrials.gov, PubMed Literature · Pipeline phase 6 · Updated 2026-07-09

Identifiers: MONDO: MONDO:0031014

Alterations

100 total · Types A (molecular) through E (functional)

Name	Type	Subtype	Direction	Frequency	Evidence	Sources	Links
ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Molecular	Gene	—	—	Emerging	Open Targets	Ensembl Open Targets
AIRE autoimmune regulator	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ALB albumin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ANPEP alanyl aminopeptidase, membrane	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ART4 ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ATP12A ATPase H+/K+ transporting non-gastric alpha2 subunit	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ATP4A ATPase H+/K+ transporting subunit alpha	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ATP4B ATPase H+/K+ transporting subunit beta	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
BRCA2 BRCA2 DNA repair associated	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CACNA1A calcium voltage-gated channel subunit alpha1 A	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CCKBR cholecystokinin B receptor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CCR5 C-C motif chemokine receptor 5	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CCR7 C-C motif chemokine receptor 7	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CD4 CD4 molecule	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CD79A CD79a molecule	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CD8A CD8 subunit alpha	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CDH1 cadherin 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CGA glycoprotein hormones, alpha polypeptide	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CHGA chromogranin A	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CLDN18 claudin 18	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CSF2 colony stimulating factor 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CTLA4 cytotoxic T-lymphocyte associated protein 4	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CTSW cathepsin W	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
CXCL8 C-X-C motif chemokine ligand 8	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
DNAH8 dynein axonemal heavy chain 8	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
EGF epidermal growth factor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FAS Fas cell surface death receptor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FASLG Fas ligand	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FCGR2A Fc gamma receptor IIa	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FLVCR1 FLVCR choline and heme transporter 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FOXP3 forkhead box P3	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
FUT1 fucosyltransferase 1 (H blood group)	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
GAST gastrin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
GCG glucagon	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
GHRL ghrelin and obestatin prepropeptide	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
GLB1 galactosidase beta 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
GYPC glycophorin C (Gerbich blood group)	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
HCCS holocytochrome c synthase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
HDC histidine decarboxylase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
HLA-C major histocompatibility complex, class I, C	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
HP haptoglobin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IFNA1 interferon alpha 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IFNG interferon gamma	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IFNL1 interferon lambda 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IFNL2 interferon lambda 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IKZF2 IKAROS family zinc finger 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL10 interleukin 10	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL13 interleukin 13	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL17A interleukin 17A	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL17F interleukin 17F	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL19 interleukin 19	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL2 interleukin 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL20 interleukin 20	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL21 interleukin 21	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL25 interleukin 25	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL26 interleukin 26	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL27 interleukin 27	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL2RA interleukin 2 receptor subunit alpha	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL4 interleukin 4	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
IL4R interleukin 4 receptor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
JAK1 Janus kinase 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
KMO kynurenine 3-monooxygenase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
MALT1 MALT1 paracaspase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
MLN motilin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
MTHFR methylenetetrahydrofolate reductase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
MUC5AC mucin 5AC, oligomeric mucus/gel-forming	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
NFKB1 nuclear factor kappa B subunit 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
NLRP3 NLR family pyrin domain containing 3	Molecular	Gene	—	—	Emerging	Open Targets	Ensembl Open Targets
OLFM4 olfactomedin 4	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
PDCD1 programmed cell death 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
PPIB peptidylprolyl isomerase B	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
PROM1 prominin 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
PTPRC protein tyrosine phosphatase receptor type C	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
REG1A regenerating family member 1 alpha	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
RO60 Ro60, Y RNA binding protein	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
S100A8 S100 calcium binding protein A8	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SELL selectin L	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SELP selectin P	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SLC18A1 solute carrier family 18 member A1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SLPI secretory leukocyte peptidase inhibitor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SOX9 SRY-box transcription factor 9	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
SSB small RNA binding exonuclease protection factor La	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
STAT3 signal transducer and activator of transcription 3	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TCN2 transcobalamin 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TFF2 trefoil factor 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TFRC transferrin receptor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TG thyroglobulin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TGFB1 transforming growth factor beta 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TGM2 transglutaminase 2	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TLR4 toll like receptor 4	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TMEM201 transmembrane protein 201	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TNF tumor necrosis factor	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TNFRSF18 TNF receptor superfamily member 18	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TNFRSF1A TNF receptor superfamily member 1A	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TPO thyroid peroxidase	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TRIM21 tripartite motif containing 21	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TSLP thymic stromal lymphopoietin	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
TTF1 transcription termination factor 1	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
VEGFB vascular endothelial growth factor B	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets
ZC3H12A zinc finger CCCH-type containing 12A	Molecular	Gene	—	—	Emerging	Open Targets	UniProt Ensembl Open Targets

Therapeutics

Direct disease associations, biomarker-linked drugs, OSMF narrative-review natural agents, and merged ranking. Only agents with registry trials or published clinical literature are shown by default.

Show agents without direct trial evidence

Drug	Type	Phase	Evidence	Score	Price (UK / US)	Trials & literature	Sources	Links
ACETAZOLAMIDE Repurposing	Small molecule	Approved	Strong	95	UK £3–£8 / 28–56 tabs · US $8–$15 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
ALBUMIN HUMAN-KJDA Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
AMPHETAMINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BEPRIDIL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
BEPRIDIL HYDROCHLORIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
BICALUTAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BISMUTH Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
BOSUTINIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CARBACHOL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CARBOPLATIN Repurposing	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	DGIdb	—
CEFADROXIL ANHYDROUS Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CELECOXIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CIPROFLOXACIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CISPLATIN Repurposing	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CLOMIPRAMINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
COLCHICINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CYCLOSPORINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	1 pubs View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DASATINIB ANHYDROUS Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
DIAZEPAM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $3–$8 / 30 tabs	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DIAZEPAM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $3–$8 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
DICHLORPHENAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DICLOFENAC SODIUM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DIETHYLSTILBESTROL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ENZALUTAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
EPIGALLOCATECHIN GALLATE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
EPIRUBICIN Repurposing	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	ChEMBL	ChEMBL Open Targets
ESOMEPRAZOLE MAGNESIUM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
ESOMEPRAZOLE SODIUM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	ChEMBL Open Targets
ESOMEPRAZOLE SODIUM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
ESOMEPRAZOLE STRONTIUM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
ETHOXZOLAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FLUCONAZOLE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
FLUMAZENIL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
GABAPENTIN Repurposing	Small molecule	Approved	Strong	95	UK £2–£5 / 28–100 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
GABAPENTIN ENACARBIL Repurposing	Small molecule	Approved	Strong	95	UK £2–£5 / 28–100 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
GADOBENATE DIMEGLUMINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
GADOFOSVESET TRISODIUM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
GEMCITABINE Repurposing	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	DGIdb	—
GENTAMICIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
HALOPERIDOL DECANOATE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
IMIPRAMINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
INDAPAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
INDOMETHACIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ISOSORBIDE DINITRATE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
LANSOPRAZOLE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
MAFENIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
MECAMYLAMINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METHAZOLAMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METHOXSALEN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METOPROLOL Repurposing	Small molecule	Approved	Strong	95	UK £2–£4 / 28 tabs · US $4–$9 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
MIANSERIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NALIDIXIC ACID Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NALOXONE HYDROCHLORIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
NAPROXEN SODIUM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
NICOTINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NIRAPARIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
NISOLDIPINE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
NORFLOXACIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
OFLOXACIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
OLAPARIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
OLMESARTAN MEDOXOMIL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
OMEPRAZOLE Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
OMEPRAZOLE MAGNESIUM Repurposing	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
PANTOPRAZOLE SODIUM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
PHENYLBUTAZONE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
PHENYTOIN Repurposing	Small molecule	Approved	Strong	95	UK £3–£8 / supply · US $6–$15 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
PRAZOSIN Repurposing	Small molecule	Approved	Strong	95	UK £2–£6 / 28–60 tabs · US $5–$12 / 30–60 tabs	—	ChEMBL	ChEMBL Open Targets
PREGABALIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
RABEPRAZOLE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
RABEPRAZOLE SODIUM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
RUCAPARIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
SACITUZUMAB GOVITECAN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
SIROLIMUS Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
SODIUM DODECYL SULFATE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	3 pubs View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
SULBACTAM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
SULOCTIDIL Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
TACROLIMUS ANHYDROUS Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TALAZOPARIB Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TAZOBACTAM Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TEMOZOLOMIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TERODILINE HYDROCHLORIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
TROGLITAZONE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
VONOPRAZAN FUMARATE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	ChEMBL Open Targets
WARFARIN Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
ZINC CHLORIDE Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
ZINC SULFATE ANHYDROUS Repurposing	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DARAPLADIB Repurposing	Small molecule	Phase III	Moderate	70	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FENRETINIDE Repurposing	Small molecule	Phase III	Moderate	70	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BETULINIC ACID Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CEPHALOSPORIN ANTIBIOTIC Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CHEMBL:CHEMBL1945287 Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
COCHINCHINENIN C Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
LINAPRAZAN Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TEGOPRAZAN Repurposing	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
ALPRENOLOL Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
AMIFLOXACIN Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BROLAMFETAMINE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CARZENIDE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DIFLOXACIN Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DIMECAMINE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ELLAGIC ACID Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ENISOPROST Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FENCAMFAMIN Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FLEROXACIN Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
IDOXIFENE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
LYSERGIDE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
MERAFLOXACIN Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TENAMFETAMINE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ZIDAPAMIDE Repurposing	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets

No therapeutics in this section.

Drug	Type	Phase	Evidence	Score	Price (UK / US)	Trials & literature	Sources	Links
ACETAZOLAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	UK £3–£8 / 28–56 tabs · US $8–$15 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
ALBUMIN HUMAN-KJDA Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
AMPHETAMINE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BEPRIDIL Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
BEPRIDIL HYDROCHLORIDE Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
BICALUTAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BISMUTH Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
BOSUTINIB Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CARBACHOL Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CARBOPLATIN Repurposing via BRCA2	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	DGIdb	—
CEFADROXIL ANHYDROUS Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CELECOXIB Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CIPROFLOXACIN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CISPLATIN Repurposing via ANPEP	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CLOMIPRAMINE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
COLCHICINE Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
CYCLOSPORINE Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	1 pubs View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DASATINIB ANHYDROUS Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
DIAZEPAM Repurposing via ALB	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $3–$8 / 30 tabs	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DIAZEPAM Repurposing via ABO	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $3–$8 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
DICHLORPHENAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DICLOFENAC SODIUM Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DIETHYLSTILBESTROL Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ENZALUTAMIDE Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
EPIGALLOCATECHIN GALLATE Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
EPIRUBICIN Repurposing via ABO	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	ChEMBL	ChEMBL Open Targets
ESOMEPRAZOLE MAGNESIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
ESOMEPRAZOLE SODIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	ChEMBL Open Targets
ESOMEPRAZOLE SODIUM Repurposing via ATP4A	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
ESOMEPRAZOLE STRONTIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
ETHOXZOLAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FLUCONAZOLE Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
FLUMAZENIL Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
GABAPENTIN Repurposing via CACNA1A	Small molecule	Approved	Strong	95	UK £2–£5 / 28–100 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
GABAPENTIN ENACARBIL Repurposing via CACNA1A	Small molecule	Approved	Strong	95	UK £2–£5 / 28–100 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
GADOBENATE DIMEGLUMINE Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
GADOFOSVESET TRISODIUM Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
GEMCITABINE Repurposing via BRCA2	Small molecule	Approved	Strong	95	Hospital / IV specialty — prices per vial or dose (often hundreds–thousands USD/GBP)	—	DGIdb	—
GENTAMICIN Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
HALOPERIDOL DECANOATE Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
IMIPRAMINE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
INDAPAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
INDOMETHACIN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ISOSORBIDE DINITRATE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
LANSOPRAZOLE Repurposing via ATP4B	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
MAFENIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
MECAMYLAMINE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METHAZOLAMIDE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METHOXSALEN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
METOPROLOL Repurposing via ABO	Small molecule	Approved	Strong	95	UK £2–£4 / 28 tabs · US $4–$9 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
MIANSERIN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NALIDIXIC ACID Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NALOXONE HYDROCHLORIDE Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
NAPROXEN SODIUM Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
NICOTINE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
NIRAPARIB Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
NISOLDIPINE Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
NORFLOXACIN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
OFLOXACIN Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
OLAPARIB Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
OLMESARTAN MEDOXOMIL Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
OMEPRAZOLE Repurposing via ATP4B	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	—
OMEPRAZOLE MAGNESIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	UK £1–£3 / 28 tabs · US $5–$12 / 30–90 tabs	—	DGIdb	ChEMBL Open Targets
PANTOPRAZOLE SODIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
PHENYLBUTAZONE Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
PHENYTOIN Repurposing via ABO	Small molecule	Approved	Strong	95	UK £3–£8 / supply · US $6–$15 / 30 tabs	—	ChEMBL	ChEMBL Open Targets
PRAZOSIN Repurposing via ABO	Small molecule	Approved	Strong	95	UK £2–£6 / 28–60 tabs · US $5–$12 / 30–60 tabs	—	ChEMBL	ChEMBL Open Targets
PREGABALIN Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
RABEPRAZOLE Repurposing via ATP4B	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
RABEPRAZOLE SODIUM Repurposing via ATP4B	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
RUCAPARIB Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
SACITUZUMAB GOVITECAN Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
SIROLIMUS Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
SODIUM DODECYL SULFATE Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	3 pubs View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
SULBACTAM Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
SULOCTIDIL Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
TACROLIMUS ANHYDROUS Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TALAZOPARIB Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TAZOBACTAM Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TEMOZOLOMIDE Repurposing via BRCA2	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TERODILINE HYDROCHLORIDE Repurposing via CACNA1A	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
TROGLITAZONE Repurposing via ABO	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
VONOPRAZAN FUMARATE Repurposing via ATP4B	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	ChEMBL Open Targets
WARFARIN Repurposing via ALB	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
ZINC CHLORIDE Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
ZINC SULFATE ANHYDROUS Repurposing via ANPEP	Small molecule	Approved	Strong	95	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	No indexed hits View evidence CT.gov search · Cochrane · PubMed	DGIdb	—
DARAPLADIB Repurposing via ABO	Small molecule	Phase III	Moderate	70	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FENRETINIDE Repurposing via ABO	Small molecule	Phase III	Moderate	70	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BETULINIC ACID Repurposing via ANPEP	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CEPHALOSPORIN ANTIBIOTIC Repurposing via ANPEP	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
CHEMBL:CHEMBL1945287 Repurposing via ALB	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
COCHINCHINENIN C Repurposing via ALB	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	ChEMBL Open Targets
LINAPRAZAN Repurposing via ATP4A	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
TEGOPRAZAN Repurposing via ATP4A	Small molecule	Phase II	Emerging	50	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	DGIdb	—
ALPRENOLOL Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
AMIFLOXACIN Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
BROLAMFETAMINE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
CARZENIDE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DIFLOXACIN Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
DIMECAMINE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ELLAGIC ACID Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ENISOPROST Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FENCAMFAMIN Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
FLEROXACIN Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
IDOXIFENE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
LYSERGIDE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
MERAFLOXACIN Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
TENAMFETAMINE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets
ZIDAPAMIDE Repurposing via ABO	Small molecule	Phase II	Emerging	45	Varies — check openprescribing.net (UK) or costplusdrugs.com / GoodRx (US)	—	ChEMBL	ChEMBL Open Targets

Alterations and therapeutics are aggregated from public databases (Open Targets, HPO, ChEMBL, DGIdb, and others). Natural agents are candidates from OSMF narrative reviews on opensourcemed.info/chronic-disease.html — not approved treatments. This page is for research orientation only — not medical advice.