Evidence Summary
Evidence Level: Preliminary
Mechanism: Enrollment: Actual, Sponsor Type: Other, Unknown / General
Safety: Limited specific safety data in these populations. Review full prescribing information and consult specialist. Many agents used off-label or investigational.
Dosing: See linked studies/trials for reported doses and durations; typical protocols vary widely.
Acetylcholinesterase inhibitor. RCT support for hemodynamics in POTS. 30-60mg TID. Cholinergic SE dose-limiting. Targeted for hyperadrenergic POTS.