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Low-Dose Naltrexone (LDN)
Also known as: Low-Dose Naltrexone (LDN)
PubChem entry
Evidence Summary
Evidence Level: Preliminary
Mechanism: Enrollment: Estimated, Immunomodulatory, Repurposed Drug, Sponsor Type: Other
Safety: Limited specific safety data in these populations. Review full prescribing information and consult specialist. Many agents used off-label or investigational.
Dosing: See linked studies/trials for reported doses and durations; typical protocols vary widely.
Investigational for listed conditions. 2 associated trial(s) and 2 study reference(s) in current data. Review primary sources and consult specialists before use.
Related Conditions
Long COVID (no page yet) · ME/CFS (no page yet) · Other Post-Viral (Post-infectious cough, Q-fever fatigue syndrome, Post-dengue fatigue, Chikungunya post-infectious, Parvovirus B19 GBS, Mycoplasma pneumoniae neurological, Herpes encephalitis sequelae, RIME, etc.) (no page yet)
Clinical Trials
2 trial(s) registered
NCT06366724: LIFT: Life Improvement Trial PHASE2 RECRUITING
NCT07285473: Low-Dose Naltrexone For ME/CFS: Dose-Finding PHASE2 NOT_YET_RECRUITING
Key Studies / References