> Creatine — Mechanism, Trials & Evidence | OSMF

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Creatine

PubChem entry

Evidence Summary

Evidence Level: Preliminary
Mechanism: Enrollment: Actual, Sponsor Type: Other, Unknown / General
Safety: Limited specific safety data in these populations. Review full prescribing information and consult specialist. Many agents used off-label or investigational.
Dosing: See linked studies/trials for reported doses and durations; typical protocols vary widely.
Creatine monohydrate 5g daily. RCT evidence (d~1) for mental fatigue and concentration in PASC. Mitochondrial support. Safe for most; monitor renal and fluid retention.

Related Conditions

ME/CFS (no page yet)

Clinical Trials

1 trial(s) registered

NCT02374112: Creatine Supplementation in Chronic Fatigue Syndrome NA ACTIVE_NOT_RECRUITING

Key Studies / References