Borrelia burgdorferi (Lyme disease)

Bacterium · Ixodes tick · 1 cohort · 1 observations · CC BY 4.0

All PAIS cohorts in this database triggered by Borrelia burgdorferi (Lyme disease). Flags mark evidentiary caveats (preprint, grey literature, patient-reported, uncontrolled, etc.).

Johns Hopkins SLICE early-Lyme cohort (Aucott/Rebman)

Prospective (inception) · N=234 · control Healthy convenience · 1 obs · max follow-up 12 mo

Measures: Impaired quality of life

Prospective inception cohort of ideally-treated early Lyme disease with a non-Lyme comparison group and a bio-repository, designed specifically to estimate the incidence of post-treatment Lyme disease. Functionally-impairing persistent symptoms occurred in 14% of treated patients vs 4% of controls, giving a rigorous denominator for PTLD that most Lyme literature lacks.