NTD Intelligence

Scabies and other ectoparasitoses

Neglected tropical disease intelligence: burden, staged therapeutics with published-evidence filter, and documented post-infectious syndrome with literature persistence rates.

Deaths / year
0
GBD (indicative unless refreshed)
DALYs / year
3,000,000
GBD
Pathogen
Mite
Post-infectious
Lasting sequela
Persistent symptoms
n/a

Post-infectious syndrome & persistent symptoms

Whether a post-acute infection syndrome is documented and the literature proportion with persistent symptoms.

Post-acute status
Secondary bacterial infection -> post-streptococcal (acute rheumatic fever, glomerulonephritis)
Classification
Lasting sequela
Onset
downstream
Persistent-symptom %
not quantified as a single figure (see notes)
Source: Romani 2015 Lancet ID

Therapeutic agents by stage

Vector control, prevention, acute treatment, and post-infectious care. Only agents with published evidence are shown by default.

Prevention

AgentTypeStatusMechanism / roleSource
Household/contact treatmentPreventionApprovedSimultaneous treatment of contactsWHO EML / standard of care

Acute phase

AgentTypeStatusMechanism / roleSource
Permethrin 5% creamTopical scabicideApprovedFirst-line topical treatmentWHO EML / standard of care
Ivermectin (oral)AnthelminticApprovedMass drug administration and crusted scabiesWHO EML / standard of care
Benzyl benzoate 25%Topical scabicideApprovedAlternative topicalWHO EML / standard of care
CHLORHEXIDINE GLUCONATEPipelineSmall moleculePhase 2Open Targets (clinical pipeline)

Post-infectious phase

AgentTypeStatusMechanism / roleSource
Secondary bacterial infection treatmentAntibioticApprovedPost-streptococcal sequelae preventionRomani 2015 Lancet ID

Associated drug targets (Open Targets): FLG, FTO, NR3C1, LY6D, PRSS53, SLC39A8

Burden: IHME GBD (indicative seed unless refreshed) · Therapeutics: curated WHO EML / SOC + Open Targets pipeline · Post-infectious data: curated peer-reviewed literature · Ontology: MONDO_0021201 · Updated 2026-07-10. Associations, not a diagnostic test.