NTD Intelligence

Taeniasis / cysticercosis

Neglected tropical disease intelligence: burden, staged therapeutics with published-evidence filter, and documented post-infectious syndrome with literature persistence rates.

Deaths / year
3,000
GBD (indicative unless refreshed)
DALYs / year
2,800,000
GBD
Pathogen
Helminth
Post-infectious
Chronic disease
Persistent symptoms
~30% of epilepsy
epilepsy cases in endemic areas

Post-infectious syndrome & persistent symptoms

Whether a post-acute infection syndrome is documented and the literature proportion with persistent symptoms.

Documented post-infectious syndrome
Neurocysticercosis -> chronic epilepsy
~30% of epilepsy
persistent symptoms — of epilepsy cases in endemic areas
Summary
Neurocysticercosis accounts for ~30% of epilepsy cases in endemic regions; a leading cause of acquired epilepsy worldwide.
Timeframe
chronic (years)
Evidence strength
strong
Classification
Chronic disease
Sources: Garcia 2020 NEJM; WHO taeniasis/cysticercosis

Therapeutic agents by stage

Vector control, prevention, acute treatment, and post-infectious care. Only agents with published evidence are shown by default.

Vector & transmission control

AgentTypeStatusMechanism / roleSource
Taenia solium control (pig management, sanitation)Vector controlApprovedBreak pig–human transmission cycleWHO

Acute phase

AgentTypeStatusMechanism / roleSource
AlbendazoleAnthelminticApprovedCysticidal for parenchymal neurocysticercosisWHO EML / standard of care
PraziquantelAnthelminticApprovedAlternative cysticidal (with caution)WHO EML / standard of care

Post-infectious phase

AgentTypeStatusMechanism / roleSource
Antiepileptic drugs (e.g. carbamazepine)AnticonvulsantApprovedSeizure control in neurocysticercosis-related epilepsyWHO EML / standard of care

Associated drug targets (Open Targets): NR3C1, AGTPBP1, TP53BP2, PSAP, CACNA1A, RELN

Burden: IHME GBD (indicative seed unless refreshed) · Therapeutics: curated WHO EML / SOC + Open Targets pipeline · Post-infectious data: curated peer-reviewed literature · Ontology: MONDO_0015484 · Updated 2026-07-10. Associations, not a diagnostic test.