/* PeptideOS — a lab report, not a magazine. Tokens from peptideos-website-spec.md §5.
   --signal is used ONLY by .signal* rules (build_peptideos.py fails the build otherwise). */
:root {
  --paper: #F6F7F5; --paper-sunk: #ECEEEA; --card: #FBFBFA;
  --ink: #14161A; --ink-muted: #545961; --rule: #D5D8D2; --rule-strong: #A9AEA6;
  --e1: #10504C; --e2: #1B6B64; --e3: #2F857B; --e4: #4E8C83;
  --e5: #8AB2AB; --e6: #A9BDB8; --e7: #BFC7C4; --e8: #9AA0A6;
  --signal: #B4341F;
  --display: "Archivo", "Helvetica Neue", Arial, sans-serif;
  --serif: "Source Serif 4", Georgia, serif;
  --mono: "JetBrains Mono", ui-monospace, "SFMono-Regular", Consolas, monospace;
  --w: 1120px;
}
*, *::before, *::after { box-sizing: border-box; }
html { -webkit-text-size-adjust: 100%; }
body { margin: 0; background: var(--paper); color: var(--ink); font: 17px/1.62 var(--serif); }
a { color: var(--e1); text-decoration-thickness: 1px; text-underline-offset: 2px; }
a:hover { text-decoration-thickness: 2px; }
:focus-visible { outline: 2px solid var(--ink); outline-offset: 2px; }
h1, h2, h3, h4 { font-family: var(--display); line-height: 1.15; letter-spacing: -0.01em; margin: 0 0 .5em; }
h1 { font-size: clamp(2rem, 4.6vw, 3.1rem); font-weight: 700; }
h2 { font-size: 1.15rem; font-weight: 700; text-transform: uppercase; letter-spacing: .06em; }
h3 { font-size: 1.12rem; font-weight: 600; }
p { margin: 0 0 1em; }
.mono, code { font-family: var(--mono); font-size: .88em; }
.muted { color: var(--ink-muted); }
.wrap { max-width: var(--w); margin: 0 auto; padding: 0 20px; }
.skip { position: absolute; left: -999px; }
.skip:focus { left: 12px; top: 12px; background: var(--ink); color: var(--paper); padding: 8px 12px; z-index: 10; }

/* masthead */
.mast { border-bottom: 1px solid var(--ink); background: var(--paper); }
.mast .wrap { display: flex; align-items: center; justify-content: space-between; gap: 16px; min-height: 58px; flex-wrap: wrap; }
.brand { font: 700 1.05rem/1 var(--display); color: var(--ink); text-decoration: none; letter-spacing: .02em; display: flex; align-items: baseline; gap: 10px; }
.brand b { font-family: var(--mono); font-weight: 600; font-size: .78rem; padding: 3px 6px; border: 1px solid var(--ink); }
.brand span { font: 400 .78rem var(--display); color: var(--ink-muted); letter-spacing: .04em; }
.mast nav { display: flex; gap: 18px; flex-wrap: wrap; font: 500 .86rem var(--display); }
.mast nav a { color: var(--ink); text-decoration: none; }
.mast nav a:hover, .mast nav a[aria-current] { text-decoration: underline; }

/* document header strip (the "report header") */
.docstrip { border-bottom: 1px solid var(--rule); background: var(--paper-sunk); font: .74rem/1.4 var(--mono); color: var(--ink-muted); }
.docstrip .wrap { display: flex; flex-wrap: wrap; gap: 6px 22px; padding-top: 7px; padding-bottom: 7px; }
.docstrip b { color: var(--ink); font-weight: 600; }

main { padding: 34px 0 60px; }
.lede { font-size: 1.14rem; max-width: 760px; }
.kicker { font: 600 .74rem/1 var(--mono); letter-spacing: .12em; text-transform: uppercase; color: var(--ink-muted); margin-bottom: 14px; }

/* tier ladder (scale, never colour-alone) */
.ladder { margin: 0 0 6px; }
.ladder ol { list-style: none; margin: 0; padding: 0; display: grid; grid-template-columns: repeat(8, 1fr); border: 1px solid var(--ink); }
.ladder li { position: relative; font: 600 .78rem/1 var(--mono); text-align: center; padding: 10px 0; border-right: 1px solid var(--rule-strong); color: var(--ink-muted); background: var(--card); }
.ladder li:last-child { border-right: 0; }
.ladder li.on { color: #fff; }
.ladder li.on.t5, .ladder li.on.t6, .ladder li.on.t7, .ladder li.on.t8 { color: var(--ink); }
.ladder li.on::after { content: "▲"; position: absolute; left: 50%; bottom: -19px; transform: translateX(-50%); font-size: .8rem; color: var(--ink); }
.ladder .cap { display: flex; justify-content: space-between; font: .7rem var(--mono); color: var(--ink-muted); margin-top: 16px; text-transform: uppercase; letter-spacing: .06em; }
.t1.on, .chip.t1 { background: var(--e1); } .t2.on, .chip.t2 { background: var(--e2); }
.t3.on, .chip.t3 { background: var(--e3); } .t4.on, .chip.t4 { background: var(--e4); }
.t5.on, .chip.t5 { background: var(--e5); } .t6.on, .chip.t6 { background: var(--e6); }
.t7.on, .chip.t7 { background: var(--e7); } .t8.on, .chip.t8 { background: var(--e8); }
.chip { display: inline-block; font: 600 .74rem/1 var(--mono); padding: 5px 7px; color: #fff; letter-spacing: .03em; }
.chip.t5, .chip.t6, .chip.t7, .chip.t8 { color: var(--ink); }
.indic { margin: 0 0 24px; }
.indic-head { display: flex; flex-wrap: wrap; align-items: baseline; gap: 6px 12px; margin-bottom: 10px; }
.indic-head h3 { margin: 0; }
.indic-head .lbl { font: .82rem var(--mono); color: var(--ink-muted); }

/* tier matrix: several claimed uses on one E1-E8 axis */
table.matrix { width: 100%; border-collapse: collapse; background: var(--card); border: 1px solid var(--ink); margin-bottom: 30px; min-width: 560px; }
table.matrix caption { text-align: left; caption-side: top; margin-bottom: 10px; }
table.matrix th, table.matrix td { border-bottom: 1px solid var(--rule); padding: 9px 6px; }
table.matrix thead th { font: 600 .74rem var(--mono); color: var(--ink-muted); text-align: center; border-bottom: 1px solid var(--ink); }
table.matrix thead th:first-child { text-align: left; padding-left: 12px; }
table.matrix tbody th { text-align: left; font: 600 .95rem/1.3 var(--display); padding-left: 12px; width: 42%; }
table.matrix tbody th .chip { margin-right: 6px; }
table.matrix td { width: 7.25%; border-left: 1px solid var(--rule); text-align: center; font: 600 .74rem var(--mono); color: #fff; }
table.matrix td.on.t5, table.matrix td.on.t6, table.matrix td.on.t7, table.matrix td.on.t8 { color: var(--ink); }
.seq.struct { font-size: clamp(.95rem, 1.8vw, 1.15rem); letter-spacing: .04em; line-height: 1.55; word-break: normal; }

/* compound hero */
.hero { padding: 6px 0 26px; border-bottom: 1px solid var(--ink); margin-bottom: 0; }
.hero + .sec { border-top: 0; }
.seq { font: 500 clamp(1.25rem, 3.4vw, 2.3rem)/1.35 var(--mono); letter-spacing: .18em; word-break: break-all; margin: 22px 0 6px; }
.seq.long { font-size: clamp(1rem, 2.2vw, 1.4rem); letter-spacing: .12em; }
.seqnote { font: .82rem var(--mono); color: var(--ink-muted); margin: 0 0 18px; }
.names { font: .86rem/1.6 var(--mono); color: var(--ink-muted); margin: 6px 0 16px; }
.classrow { display: flex; flex-wrap: wrap; gap: 6px; margin: 14px 0 0; padding: 0; list-style: none; }
.classrow li { font: .76rem/1 var(--mono); border: 1px solid var(--rule-strong); padding: 6px 8px; background: var(--card); }
.classrow li b { font-weight: 600; }
.cls-A b { color: var(--e1); }

/* sections */
.sec { padding: 26px 0 8px; border-top: 1px solid var(--rule); }
.sec > h2 { display: flex; gap: 12px; align-items: baseline; }
.sec > h2 .n { font: 600 .74rem var(--mono); color: var(--ink-muted); }
.notice { border: 1px solid var(--ink); background: var(--card); padding: 14px 16px; margin: 0 0 20px; font-size: .97rem; }
.notice strong { font-family: var(--display); }

table.reg { width: 100%; border-collapse: collapse; font-size: .92rem; background: var(--card); }
table.reg th, table.reg td { text-align: left; vertical-align: top; padding: 10px 10px; border-bottom: 1px solid var(--rule); }
table.reg th { font: 600 .72rem var(--mono); text-transform: uppercase; letter-spacing: .06em; color: var(--ink-muted); border-bottom: 1px solid var(--ink); }
table.reg td.j { font: 600 .82rem var(--mono); white-space: nowrap; }
table.reg .st { font: 600 .8rem var(--display); }
table.reg blockquote { margin: 6px 0 0; padding-left: 10px; border-left: 2px solid var(--rule-strong); font-size: .86rem; color: var(--ink-muted); }
table.reg .src { font: .74rem var(--mono); color: var(--ink-muted); display: block; margin-top: 6px; }
.unver { color: var(--ink-muted); font-style: italic; }

.counts { display: flex; flex-wrap: wrap; gap: 0; border: 1px solid var(--rule-strong); margin: 4px 0 14px; background: var(--card); }
.counts div { padding: 8px 14px; border-right: 1px solid var(--rule); }
.counts div:last-child { border-right: 0; }
.counts b { display: block; font: 600 1.25rem/1.2 var(--mono); }
.counts span { font: .7rem var(--mono); color: var(--ink-muted); text-transform: uppercase; letter-spacing: .05em; }
.absent { font-family: var(--display); font-weight: 600; font-size: 1.05rem; border-left: 4px solid var(--e8); padding: 4px 0 4px 12px; margin: 0 0 12px; }
ol.cites, ul.cites { padding-left: 1.4em; font-size: .92rem; }
ol.cites li, ul.cites li { margin-bottom: 8px; }
.cites .f { color: var(--ink-muted); }
.ref { font: .74rem var(--mono); vertical-align: super; text-decoration: none; }

.grade { display: inline-flex; gap: 10px; align-items: baseline; border: 1px solid var(--ink); padding: 8px 12px; background: var(--card); margin-bottom: 12px; }
.grade b { font: 600 1rem var(--mono); }
.signals { list-style: none; padding: 0; margin: 0; }
.signal { border-left: 4px solid var(--signal); background: var(--card); padding: 10px 14px; margin: 0 0 10px; }
.signal-title { color: var(--signal); font-family: var(--display); font-weight: 700; }
.unknowns { padding-left: 1.3em; }
.unknowns li { margin-bottom: 6px; }
.mech { color: var(--ink-muted); font-size: .95rem; }
.trials { width: 100%; border-collapse: collapse; font-size: .88rem; background: var(--card); }
.trials td, .trials th { padding: 7px 8px; border-bottom: 1px solid var(--rule); text-align: left; vertical-align: top; }
.trials th { font: 600 .7rem var(--mono); text-transform: uppercase; color: var(--ink-muted); border-bottom: 1px solid var(--ink); }
.trials td:first-child { font-family: var(--mono); white-space: nowrap; }
.tablewrap { overflow-x: auto; -webkit-overflow-scrolling: touch; }

/* index grid — the thesis */
.thesis { display: grid; grid-template-columns: 1.4fr 1fr; gap: 34px; align-items: end; padding-bottom: 26px; border-bottom: 1px solid var(--ink); margin-bottom: 22px; }
.stat { font: 700 clamp(3rem, 9vw, 5.6rem)/0.9 var(--display); letter-spacing: -0.03em; }
.stat small { display: block; font: 500 .95rem/1.4 var(--serif); letter-spacing: 0; margin-top: 10px; color: var(--ink-muted); }
.ramp { display: grid; grid-template-columns: repeat(8, 1fr); gap: 2px; margin-top: 16px; }
.ramp div { height: 64px; display: flex; align-items: flex-end; justify-content: center; font: 600 .7rem var(--mono); padding-bottom: 4px; position: relative; }
.ramp .bar { position: absolute; left: 0; right: 0; bottom: 18px; }
.ramp .lab { position: relative; }
.filters { display: flex; flex-wrap: wrap; gap: 10px 16px; align-items: end; padding: 14px 0 18px; border-bottom: 1px solid var(--rule); margin-bottom: 20px; }
.filters label { display: flex; flex-direction: column; gap: 4px; font: 600 .7rem var(--mono); text-transform: uppercase; letter-spacing: .06em; color: var(--ink-muted); }
.filters select { font: .9rem var(--display); padding: 7px 8px; border: 1px solid var(--rule-strong); background: var(--card); color: var(--ink); min-width: 150px; }
.filters .count { font: .82rem var(--mono); color: var(--ink-muted); margin-left: auto; }
.band { margin: 0 0 26px; }
.band > h2 { display: flex; align-items: center; gap: 10px; font-size: .86rem; }
.band > h2 .chip { font-size: .72rem; }
.grid { display: grid; grid-template-columns: repeat(auto-fill, minmax(250px, 1fr)); gap: 10px; }
.card { display: flex; flex-direction: column; gap: 8px; text-decoration: none; color: var(--ink); background: var(--card); border: 1px solid var(--rule-strong); border-top: 6px solid var(--e8); padding: 12px 14px 12px; min-height: 150px; }
.card:hover { border-color: var(--ink); }
.card.b1 { border-top-color: var(--e1); } .card.b2 { border-top-color: var(--e2); } .card.b3 { border-top-color: var(--e3); }
.card.b4 { border-top-color: var(--e4); } .card.b5 { border-top-color: var(--e5); } .card.b6 { border-top-color: var(--e6); }
.card.b7 { border-top-color: var(--e7); } .card.b8 { background: var(--paper-sunk); }
.card h3 { margin: 0; font-size: 1.05rem; }
.card .alt { font: .72rem var(--mono); color: var(--ink-muted); }
.card .meta { margin-top: auto; display: flex; justify-content: space-between; font: .7rem var(--mono); color: var(--ink-muted); gap: 8px; }
.mini { display: grid; grid-template-columns: repeat(8, 1fr); gap: 2px; }
.mini i { height: 8px; background: var(--paper-sunk); border: 1px solid var(--rule); }
.mini i.on { border-color: var(--ink); }
.mini i.on.t1 { background: var(--e1); } .mini i.on.t2 { background: var(--e2); } .mini i.on.t3 { background: var(--e3); }
.mini i.on.t4 { background: var(--e4); } .mini i.on.t5 { background: var(--e5); } .mini i.on.t6 { background: var(--e6); }
.mini i.on.t7 { background: var(--e7); } .mini i.on.t8 { background: var(--e8); }
.card .ind { font: .78rem/1.35 var(--serif); color: var(--ink-muted); }
.clsbadge { font: 600 .64rem/1 var(--mono); border: 1px solid var(--ink); padding: 3px 5px; text-transform: uppercase; letter-spacing: .04em; white-space: nowrap; flex-shrink: 0; }
[hidden] { display: none !important; }

/* prose pages */
.prose { max-width: 760px; }
.prose h2 { margin-top: 1.8em; }
.prose table { border-collapse: collapse; width: 100%; font-size: .92rem; margin: 0 0 1.2em; background: var(--card); }
.prose th, .prose td { text-align: left; padding: 8px 10px; border-bottom: 1px solid var(--rule); vertical-align: top; }
.prose th { font: 600 .72rem var(--mono); text-transform: uppercase; color: var(--ink-muted); border-bottom: 1px solid var(--ink); }
.log { list-style: none; padding: 0; }
.log li { border-top: 1px solid var(--rule); padding: 14px 0; }
.log time { font: 600 .8rem var(--mono); color: var(--ink-muted); display: block; margin-bottom: 4px; }
.dl { display: flex; flex-wrap: wrap; gap: 10px; margin: 0 0 1.2em; }
.dl a { font: 600 .84rem var(--mono); border: 1px solid var(--ink); padding: 8px 12px; text-decoration: none; color: var(--ink); background: var(--card); }

/* footer */
.foot { border-top: 1px solid var(--ink); padding: 26px 0 40px; font: .86rem/1.55 var(--display); color: var(--ink-muted); }
.foot .cols { display: grid; grid-template-columns: 2fr 1fr 1fr; gap: 24px; }
.foot a { color: var(--ink); }
.foot ul { list-style: none; padding: 0; margin: 0; }
.foot li { margin-bottom: 4px; }
.foot .coi { font-family: var(--serif); }

@media (max-width: 760px) {
  body { font-size: 16px; }
  .thesis { grid-template-columns: 1fr; gap: 18px; }
  .foot .cols { grid-template-columns: 1fr; }
  .ladder li { font-size: .66rem; padding: 9px 0; }
  .ladder .cap span:nth-child(2) { display: none; }
  .filters select { min-width: 0; width: 100%; }
  .filters label { flex: 1 1 140px; }
  .filters .count { margin-left: 0; width: 100%; }
  table.reg thead { display: none; }
  table.reg, table.reg tbody, table.reg tr, table.reg td { display: block; width: 100%; }
  table.reg tr { border-bottom: 1px solid var(--ink); padding: 6px 0; }
  table.reg td { border: 0; padding: 4px 10px; }
  .mast nav { gap: 12px; font-size: .8rem; }
}
@media (prefers-reduced-motion: reduce) { * { transition: none !important; animation: none !important; } }
@media print {
  @page { margin: 16mm; }
  body { background: #fff; font-size: 10.5pt; }
  .mast nav, .filters, .skip, .noprint { display: none !important; }
  .card, .notice, table.reg, .counts, .signal, .ladder li { background: #fff !important; }
  .ladder li.on { -webkit-print-color-adjust: exact; print-color-adjust: exact; }
  a { color: var(--ink); }
  .sec { break-inside: avoid-page; }
  .citeurl::after { content: " <" attr(href) ">"; font: 8pt var(--mono); word-break: break-all; }
}