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PeptideOS

Evidence, regulatory status, and purity data for therapeutic peptides. Disinterested reference, no vendors.

Every peptide resource on the internet today is a storefront with a literature review bolted to the front of it. When you search for a peptide, the top results are affiliate wikis and vendor blogs — written by people who make money when you buy.

This is different. We make zero dollars when you do anything. We are funded by grants and public foundations only. We answer three questions, and only these three:

Evidence

What is the actual evidence that it does anything in humans? Evidence tier (E1–E8) displayed prominently on every page.

Regulatory Status

Is it approved? In which jurisdictions? Is it investigational? All regulatory claims cited to primary sources (FDA, EMA, etc.).

Purity

If you obtained it on the gray market, what is actually in the vial? Annual purity testing programme, vendors named.

The Evidence Tier System

Every compound is positioned on the same eight-step scale. No exceptions. The scale runs from established evidence (E1) to no evidence at all (E8).

E1
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E2
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E3
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E4
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E5
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E6
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E7
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E8

E1: Multiple RCTs, consistent results | E2: One RCT | E3: Small/conflicting RCTs | E4: Uncontrolled trials | E5: Case series | E6: Animal models | E7: In vitro | E8: No evidence

Three Classes of Peptides

Peptides with regulatory approval in at least one major jurisdiction. Standard drug monographs: indications, approved doses (from the label), pivotal trials, safety profile.

Examples: semaglutide (Ozempic), tirzepatide (Mounjaro), teriparatide (Forteo), bremelanotide (Vyleesi)

Governance & Transparency

All Editorial Decisions Have a Signature

Every compound record is reviewed by a named editor, dated. Corrections are logged publicly. Funding is disclosed. We are funded by grants and public foundations only — zero dollars from vendors.

Purity Testing Programme

Gray-market peptides are purchased blindly from retail vendors, tested by independent labs (LC-MS/MS for identity and purity, endotoxin, sterility), and results are published with vendor names. This is primary data, not aggregation — the only thing on this topic that can't be copied by affiliate sites because it requires actually buying the stuff and running the assays.

Annual purity surveys per compound class: Results published here and in peer-reviewed journals.

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