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<rss xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title>Other post-viral clinical trials: new and updated - Open Source Medicine Foundation</title><link>https://research.opensourcemed.info/other-post-viral.html</link><description>ClinicalTrials.gov records for Other post-viral and post-infectious syndromes that were newly registered or updated, as tracked by the Open Source Medicine Foundation research tracker. The 30 most recently updated trials, newest first.</description><language>en</language><lastBuildDate>Fri, 09 Oct 2026 11:21:14 +0000</lastBuildDate><generator>OSMF build_condition_feeds.py</generator><ttl>1440</ttl><atom:link href="https://research.opensourcemed.info/feeds/other-post-viral.xml" rel="self" type="application/rss+xml" /><image><url>https://opensourcemed.info/favicon.png</url><title>Other post-viral clinical trials: new and updated - Open Source Medicine Foundation</title><link>https://research.opensourcemed.info/other-post-viral.html</link></image><item><title>NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease</title><link>https://clinicaltrials.gov/study/NCT07398508</link><guid isPermaLink="false">NCT07398508:2026-10-05</guid><pubDate>Mon, 05 Oct 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Phase 1 · Droxidopa Oral Product — This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of Menkes disease through early Copper Histidinate treatment. The investigat…</description></item><item><title>Cardiac Involvement in Wilson's Disease</title><link>https://clinicaltrials.gov/study/NCT05493605</link><guid isPermaLink="false">NCT05493605:2026-10-01</guid><pubDate>Thu, 01 Oct 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope — Heart damage by copper accumulation has been reported in Wilson's Disease. However, the disease epidemiology is still poorly understood. A number of studies on pediatric populations have not shown any significant cardiac involvement apart from early dysautonomia. This could suggest that the clinical…</description></item><item><title>Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition</title><link>https://clinicaltrials.gov/study/NCT07468604</link><guid isPermaLink="false">NCT07468604:2026-09-29</guid><pubDate>Tue, 29 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Phase 4 · 5 Ml Of 0.25% Bupivacaine With Epinephrine — Post-COVID Condition (PCC) affects roughly 2.1 million Canadians, carrying an annual economic burden of CAD $7.8-50.6 billion. It presents across multiple organ systems with symptoms including fatigue, brain fog, palpitations, and orthostatic intolerance, at an annual cost of CAD $1,675-$7,340 per c…</description></item><item><title>Fighting Fatigue in Multiple Sclerosis: TMS vs. tDCS Efficacy.</title><link>https://clinicaltrials.gov/study/NCT07842302</link><guid isPermaLink="false">NCT07842302:2026-09-25</guid><pubDate>Fri, 25 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Not applicable · Tms, Tdcs — Multiple Sclerosis (MS) is a chronic neurological disease impacting 2.8 million individuals globally, with fatigue being its most debilitating symptom, reported by 75% of patients. Despite its prevalence, the pathophysiology of MS-related fatigue remains poorly understood, and current pharmacologica…</description></item><item><title>RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome</title><link>https://clinicaltrials.gov/study/NCT07837804</link><guid isPermaLink="false">NCT07837804:2026-09-24</guid><pubDate>Thu, 24 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Not applicable · Bilateral Sequential Stellate Ganglion Block — RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing. The study has two parts. In the first part, patients with POTS and healthy volunteer…</description></item><item><title>fMRI in Postural Tachycardia Syndrome</title><link>https://clinicaltrials.gov/study/NCT04137757</link><guid isPermaLink="false">NCT04137757:2026-09-24</guid><pubDate>Thu, 24 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Active Not Recruiting</category><description>Active Not Recruiting · Not applicable · Lower Body Negative Pressure — Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance in the United States. This is a disabling disorder characterized by an excessive increase in heart rate upon standing that is accompanied by symptoms such as dizziness and fatigue. One of the most…</description></item><item><title>The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity</title><link>https://clinicaltrials.gov/study/NCT05618067</link><guid isPermaLink="false">NCT05618067:2026-09-16</guid><pubDate>Wed, 16 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Not applicable · Breathing Exercise Training — This study is being to see if participating in breathing exercise training and practicing this training will help with Postural tachycardia syndrome (POTS). The information may help doctors to learn more about how the different parts of people's brains communicate.</description></item><item><title>Study Evaluating the Effect of UCB8600 on Mast Cell Activation in the Human Gut</title><link>https://clinicaltrials.gov/study/NCT07655375</link><guid isPermaLink="false">NCT07655375:2026-09-10</guid><pubDate>Thu, 10 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Sample Collection — Study evaluating the effect of UCB8600 on mast cell activation in the human gut: IBS is a disease characterized by abdominal pain and a change in stool. Treatment is limited to an adapted life style, dietary changes and medication to lessen cramps (spasmolytica), all of which have seen limited to no…</description></item><item><title>The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome</title><link>https://clinicaltrials.gov/study/NCT05554107</link><guid isPermaLink="false">NCT05554107:2026-09-03</guid><pubDate>Thu, 03 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Training Program — Postural orthostatic tachycardia syndrome (POTS) is a disorder of unknown origin characterized by orthostatic intolerance and increased heart rate (HR) of ≥ 30 beats/minute during orthostasis in the absence of orthostatic hypotension. In addition to the orthostatic intolerance and tachycardia, patie…</description></item><item><title>Brain Research and Integrative Neuroscience Network for COVID-19</title><link>https://clinicaltrials.gov/study/NCT06517706</link><guid isPermaLink="false">NCT06517706:2026-09-01</guid><pubDate>Tue, 01 Sep 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Completed</category><description>Completed · Not applicable · Combination Of Tdcs, Categorization Program — The aim of the experimental study is to investigate two interventions for the management of cognitive symptoms resulting from long COVID. Participants will be randomly assigned into two interventions. 1. Categorization Program (CP) training with active tDCS or 2. Categorization Program training with…</description></item><item><title>Study to Evaluate the Efficacy of 2LEBV® and 2LXFS® on Asthenia in Patients With an Epstein-Barr Virus Infection</title><link>https://clinicaltrials.gov/study/NCT04308278</link><guid isPermaLink="false">NCT04308278:2026-08-31</guid><pubDate>Mon, 31 Aug 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Phase 4 · 2Lebv® / 2Lxfs® — Worldwide, 95% of adults are infected with Epstein-Barr Virus (EBV). These infections may cause different diseases. In most cases, EBV infection is asymptomatic because of a highly effective host immune response. Some individuals develop infectious mononucleosis (a self-limiting lymphoproliferative …</description></item><item><title>Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2</title><link>https://clinicaltrials.gov/study/NCT05350774</link><guid isPermaLink="false">NCT05350774:2026-08-26</guid><pubDate>Wed, 26 Aug 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Enrolling By Invitation</category><description>Enrolling By Invitation · Phase 2 · Iv Normal Saline, Iv Immunoglobulin — Background: COVID-19 can cause problems in different parts of the body. For most people, it causes fevers or trouble breathing. Some people might not recover all the way. Researchers want to see if a treatment can help with people who have recovered from COVID-19 but still have symptoms ("Long COVID…</description></item><item><title>Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial</title><link>https://clinicaltrials.gov/study/NCT07757555</link><guid isPermaLink="false">NCT07757555:2026-08-12</guid><pubDate>Wed, 12 Aug 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Early phase 1 · Guanfacine, Cromolyn Sodium — The goal of this clinical trial is to learn whether guanfacine or cromolyn sodium can improve symptoms and physical functioning in adults with Postural Orthostatic Tachycardia Syndrome (POTS). Both medications are FDA-approved for other conditions but are investigational for the treatment of POTS. T…</description></item><item><title>Blood Pressure Effects on Cognition and Brain Blood Flow in PD</title><link>https://clinicaltrials.gov/study/NCT05400174</link><guid isPermaLink="false">NCT05400174:2026-08-07</guid><pubDate>Fri, 07 Aug 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Tilt Table — Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing. About one-third of peopl…</description></item><item><title>Autoimmune Basis for Postural Tachycardia Syndrome</title><link>https://clinicaltrials.gov/study/NCT05043051</link><guid isPermaLink="false">NCT05043051:2026-07-29</guid><pubDate>Wed, 29 Jul 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Completed</category><description>Completed · Not applicable · Vagal Stimulation — The purpose of this study is to test the hypothesis that an antibody-mediated autoimmune reaction will cause symptoms of autonomic dysfunction in some patients with postural tachycardia syndrome (POTS). The investigators further hypothesize that electrical stimulation of the vagus nerve will improve…</description></item><item><title>Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)</title><link>https://clinicaltrials.gov/study/NCT06593600</link><guid isPermaLink="false">NCT06593600:2026-07-21</guid><pubDate>Tue, 21 Jul 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Completed</category><description>Completed · Phase 2 · Regn7544 — This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on participants with POTS. The aim of the study is to see how safe, tolerable, and effective the study drug is. The study is looking at several other research questions, including: * How the st…</description></item><item><title>Vagal Stimulation in POTS</title><link>https://clinicaltrials.gov/study/NCT03124355</link><guid isPermaLink="false">NCT03124355:2026-07-13</guid><pubDate>Mon, 13 Jul 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Active Not Recruiting</category><description>Active Not Recruiting · Phase 1 · Pyridostigmine Pill, Galantamine Pill, Vagal Stimulation — The purpose of this study is to investigate how the electrical stimulation of a nerve in the skin of the earlobe (transcutaneous vagal nerve stimulation), alone or in combination with two medications (galantamine and pyridostigmine), affects the way the autonomic (involuntary) nervous system control…</description></item><item><title>Inhaled Cromolyn Sodium in Patients With Locally Advanced Lung Cancer</title><link>https://clinicaltrials.gov/study/NCT07675876</link><guid isPermaLink="false">NCT07675876:2026-07-01</guid><pubDate>Wed, 01 Jul 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Phase 1 · Cromolyn Sodium — Brief Summary This prospective, open-label pilot study is designed to evaluate the safety, tolerability, feasibility, and preliminary clinical activity of inhaled cromolyn sodium administered by dry powder inhalation in participants with locally advanced lung cancer. Cromolyn sodium is an FDA-approv…</description></item><item><title>Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain</title><link>https://clinicaltrials.gov/study/NCT04827992</link><guid isPermaLink="false">NCT04827992:2026-06-24</guid><pubDate>Wed, 24 Jun 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Completed</category><description>Completed · Not applicable · Cannabis, Prescription Opioid Taper Support — This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain intensity and interference when added to a 24-week behavioral intervention…</description></item><item><title>PASCA-MM Study. Impact of the PASCA (PArcours de Santé au Cours du CAncer) Program on Complications Associated With Multiple Myeloma and/or Its Treatments in the Context of a First Hematopoietic Stem Cell Autograft, in Adults Aged 18 to 70.</title><link>https://clinicaltrials.gov/study/NCT05947136</link><guid isPermaLink="false">NCT05947136:2026-06-11</guid><pubDate>Thu, 11 Jun 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Interpretation Of The Results From The Detection Visit, Explaining Detection Results And Referrals To The Patient, Early Medical Care Through The Network — This is a prospective, multicentre, phase III, randomised, controlled intervention study. Two groups of patients with equal numbers will be studied and each patient will be allocated to one of the two groups described below by randomisation (ratio 1:1). Each patient will be allocated to one of the t…</description></item><item><title>Fareon Open Label Device Clinical Trial</title><link>https://clinicaltrials.gov/study/NCT07600320</link><guid isPermaLink="false">NCT07600320:2026-05-20</guid><pubDate>Wed, 20 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Not applicable · Fareon Device — The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis (ME/CFS), and other neurodegenerative diagnoses including but not limit…</description></item><item><title>Beta-3 Enhanced Autonomic Therapy for POTS</title><link>https://clinicaltrials.gov/study/NCT07585513</link><guid isPermaLink="false">NCT07585513:2026-05-13</guid><pubDate>Wed, 13 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Phase 2 · Mirabegron — The study will test the hypothesis that mirabegron is more effective than a placebo in alleviating postural orthostatic tachycardia (POTS) symptoms.</description></item><item><title>DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury</title><link>https://clinicaltrials.gov/study/NCT07567274</link><guid isPermaLink="false">NCT07567274:2026-05-13</guid><pubDate>Wed, 13 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Enrolling By Invitation</category><description>Enrolling By Invitation · Phase 2 · Dmso-Based Otic Solution With Betahistine, Dexamethasone, And Lidocaine, N-Acetylcysteine (NAC) — The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to long-COVID (post-acute sequelae of SARS-CoV-2) or post-COVID-19 vaccine injury. Participants have bothersome tinnitus that has not impro…</description></item><item><title>Effects of Breathing Retraining Exercises in Pregnant Females With Postural Orthostatic Tachycardia Syndrome.</title><link>https://clinicaltrials.gov/study/NCT07579026</link><guid isPermaLink="false">NCT07579026:2026-05-11</guid><pubDate>Mon, 11 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Diaphragmatic Breathing Exercise — Postural orthostatic tachycardia POTS is characterized by excessive increase in heart rate when moving from lying to standing position, often accompanied by symptoms such as dizziness, fatigue, brain fog, lightheadedness, rapid heartbeat and palpitation.it most commonly effects the females of reprod…</description></item><item><title>Non-invasive Vagus Nerve Stimulation for Chronic Musculoskeletal Pain</title><link>https://clinicaltrials.gov/study/NCT07409363</link><guid isPermaLink="false">NCT07409363:2026-05-11</guid><pubDate>Mon, 11 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Not Yet Recruiting</category><description>Not Yet Recruiting · Not applicable · Active Vagus Nerve Stimulation — Chronic musculoskeletal (MSK) pain affects an estimated 20-33% of the global population and is frequently associated with autonomic nervous system dysfunction, characterised by symptoms such as orthostatic intolerance, palpitations, gastrointestinal dysmotility, and fatigue. Conventional treatments …</description></item><item><title>The Effects of Chiropractic in a Population With High Central Adiposity</title><link>https://clinicaltrials.gov/study/NCT06208163</link><guid isPermaLink="false">NCT06208163:2026-05-08</guid><pubDate>Fri, 08 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Completed</category><description>Completed · Not applicable · Chiropractic — Since 1980, the global prevalence of obesity, commonly defined as a body mass index (BMI) of 30 or higher, has doubled. Importantly, high levels of central adiposity (i.e., abdominal fat) is associated with numerous PNI-related sequelae, including increased levels of psychological distress, cognitiv…</description></item><item><title>CAlgary SAlt for POTS</title><link>https://clinicaltrials.gov/study/NCT05924646</link><guid isPermaLink="false">NCT05924646:2026-05-07</guid><pubDate>Thu, 07 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Microcystalline Cellulose Capsules — Many patients with postural orthostatic tachycardia syndrome (POTS) have decreased plasma volume. Current POTS guidelines recommend \~10 g of salt and 2-3 L of fluid per day. Despite this recommendation, there is no long term data evaluating the use of salt in POTS. This randomized, placebo-controll…</description></item><item><title>NC Testing in LC &amp; POTS</title><link>https://clinicaltrials.gov/study/NCT05914649</link><guid isPermaLink="false">NCT05914649:2026-05-07</guid><pubDate>Thu, 07 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Iv Normal Saline — Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or "Long COVID") experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive function in patients with POTS and Long COVID compared …</description></item><item><title>Compression Garments in the Community With POTS</title><link>https://clinicaltrials.gov/study/NCT04881318</link><guid isPermaLink="false">NCT04881318:2026-05-07</guid><pubDate>Thu, 07 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Waist-High Compression Tights, Abdominal Compression Garments, Medications That Modulate Heart Rate And Blood Pressure — Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that particip…</description></item><item><title>Hypercapnia and Orthostatic Tolerance in Postural Orthostatic Tachycardia Syndrome</title><link>https://clinicaltrials.gov/study/NCT04271878</link><guid isPermaLink="false">NCT04271878:2026-05-07</guid><pubDate>Thu, 07 May 2026 08:00:00 +0000</pubDate><category>Other post-viral</category><category>Recruiting</category><description>Recruiting · Not applicable · Respiract™ System — The mechanism behind postural orthostatic tachycardia syndrome (POTS) involves many causes including a sympathetic nervous system problem. Blood gases, like carbon dioxide (CO2), have an important effect on sympathetic activation. The purpose of this research study is to determine if higher CO2 leve…</description></item></channel></rss>