{ "version": "https://jsonfeed.org/version/1.1", "title": "Other post-viral clinical trials: new and updated - Open Source Medicine Foundation", "home_page_url": "https://research.opensourcemed.info/other-post-viral.html", "feed_url": "https://research.opensourcemed.info/feeds/other-post-viral.json", "description": "ClinicalTrials.gov records for Other post-viral and post-infectious syndromes that were newly registered or updated, as tracked by the Open Source Medicine Foundation research tracker. The 30 most recently updated trials, newest first.", "language": "en", "icon": "https://opensourcemed.info/favicon.png", "favicon": "https://opensourcemed.info/favicon.png", "authors": [ { "name": "Open Source Medicine Foundation", "url": "https://opensourcemed.info" } ], "items": [ { "id": "NCT07398508:2026-10-05", "url": "https://clinicaltrials.gov/study/NCT07398508", "title": "NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease", "content_text": "Recruiting · Phase 1 · Droxidopa Oral Product — This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of Menkes disease through early Copper Histidinate treatment. The investigat…", "summary": "Recruiting · Phase 1 · Droxidopa Oral Product — This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of Menkes disease through ea", "tags": [ "Other post-viral", "Recruiting", "Droxidopa Oral Product" ], "_osmf": { "nct_id": "NCT07398508", "status": "RECRUITING", "phase": "PHASE1", "start_date": "2026-08-10", "last_updated": "2026-10-05", "agents": [ "Droxidopa Oral Product" ] }, "date_published": "2026-10-05T08:00:00+00:00", "date_modified": "2026-10-05T08:00:00+00:00" }, { "id": "NCT05493605:2026-10-01", "url": "https://clinicaltrials.gov/study/NCT05493605", "title": "Cardiac Involvement in Wilson's Disease", "content_text": "Recruiting · Not applicable · Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope — Heart damage by copper accumulation has been reported in Wilson's Disease. However, the disease epidemiology is still poorly understood. A number of studies on pediatric populations have not shown any significant cardiac involvement apart from early dysautonomia. This could suggest that the clinical…", "summary": "Recruiting · Not applicable · Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope — Heart damage by copper accumulation has been reported in Wilson's Disease. However, the disease epidemiology is still poorly understood. A number of studies on pedi", "tags": [ "Other post-viral", "Recruiting", "Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope" ], "_osmf": { "nct_id": "NCT05493605", "status": "RECRUITING", "phase": "NA", "start_date": "2023-03-02", "last_updated": "2026-10-01", "agents": [ "Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope" ] }, "date_published": "2026-10-01T08:00:00+00:00", "date_modified": "2026-10-01T08:00:00+00:00" }, { "id": "NCT07468604:2026-09-29", "url": "https://clinicaltrials.gov/study/NCT07468604", "title": "Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition", "content_text": "Recruiting · Phase 4 · 5 Ml Of 0.25% Bupivacaine With Epinephrine — Post-COVID Condition (PCC) affects roughly 2.1 million Canadians, carrying an annual economic burden of CAD $7.8-50.6 billion. It presents across multiple organ systems with symptoms including fatigue, brain fog, palpitations, and orthostatic intolerance, at an annual cost of CAD $1,675-$7,340 per c…", "summary": "Recruiting · Phase 4 · 5 Ml Of 0.25% Bupivacaine With Epinephrine — Post-COVID Condition (PCC) affects roughly 2.1 million Canadians, carrying an annual economic burden of CAD $7.8-50.6 billion. It presents across multiple organ systems with symptoms including fatigue, brain fog, palpitations, and o", "tags": [ "Other post-viral", "Recruiting", "5 Ml Of 0.25% Bupivacaine With Epinephrine" ], "_osmf": { "nct_id": "NCT07468604", "status": "RECRUITING", "phase": "PHASE4", "start_date": "2026-05-19", "last_updated": "2026-09-29", "agents": [ "5 Ml Of 0.25% Bupivacaine With Epinephrine" ] }, "date_published": "2026-09-29T08:00:00+00:00", "date_modified": "2026-09-29T08:00:00+00:00" }, { "id": "NCT07842302:2026-09-25", "url": "https://clinicaltrials.gov/study/NCT07842302", "title": "Fighting Fatigue in Multiple Sclerosis: TMS vs. tDCS Efficacy.", "content_text": "Not Yet Recruiting · Not applicable · Tms, Tdcs — Multiple Sclerosis (MS) is a chronic neurological disease impacting 2.8 million individuals globally, with fatigue being its most debilitating symptom, reported by 75% of patients. Despite its prevalence, the pathophysiology of MS-related fatigue remains poorly understood, and current pharmacologica…", "summary": "Not Yet Recruiting · Not applicable · Tms, Tdcs — Multiple Sclerosis (MS) is a chronic neurological disease impacting 2.8 million individuals globally, with fatigue being its most debilitating symptom, reported by 75% of patients. Despite its prevalence, the pathophysiology of MS-related fatigue rem", "tags": [ "Other post-viral", "Not Yet Recruiting", "Tms", "Tdcs" ], "_osmf": { "nct_id": "NCT07842302", "status": "NOT_YET_RECRUITING", "phase": "NA", "start_date": "2026-09", "last_updated": "2026-09-25", "agents": [ "Tms", "Tdcs" ] }, "date_published": "2026-09-25T08:00:00+00:00", "date_modified": "2026-09-25T08:00:00+00:00" }, { "id": "NCT07837804:2026-09-24", "url": "https://clinicaltrials.gov/study/NCT07837804", "title": "RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome", "content_text": "Not Yet Recruiting · Not applicable · Bilateral Sequential Stellate Ganglion Block — RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing. The study has two parts. In the first part, patients with POTS and healthy volunteer…", "summary": "Not Yet Recruiting · Not applicable · Bilateral Sequential Stellate Ganglion Block — RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing.", "tags": [ "Other post-viral", "Not Yet Recruiting", "Bilateral Sequential Stellate Ganglion Block" ], "_osmf": { "nct_id": "NCT07837804", "status": "NOT_YET_RECRUITING", "phase": "NA", "start_date": "2026-10-01", "last_updated": "2026-09-24", "agents": [ "Bilateral Sequential Stellate Ganglion Block" ] }, "date_published": "2026-09-24T08:00:00+00:00", "date_modified": "2026-09-24T08:00:00+00:00" }, { "id": "NCT04137757:2026-09-24", "url": "https://clinicaltrials.gov/study/NCT04137757", "title": "fMRI in Postural Tachycardia Syndrome", "content_text": "Active Not Recruiting · Not applicable · Lower Body Negative Pressure — Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance in the United States. This is a disabling disorder characterized by an excessive increase in heart rate upon standing that is accompanied by symptoms such as dizziness and fatigue. One of the most…", "summary": "Active Not Recruiting · Not applicable · Lower Body Negative Pressure — Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance in the United States. This is a disabling disorder characterized by an excessive increase in heart rate upon standing that i", "tags": [ "Other post-viral", "Active Not Recruiting", "Lower Body Negative Pressure" ], "_osmf": { "nct_id": "NCT04137757", "status": "ACTIVE_NOT_RECRUITING", "phase": "NA", "start_date": "2022-02-18", "last_updated": "2026-09-24", "agents": [ "Lower Body Negative Pressure" ] }, "date_published": "2026-09-24T08:00:00+00:00", "date_modified": "2026-09-24T08:00:00+00:00" }, { "id": "NCT05618067:2026-09-16", "url": "https://clinicaltrials.gov/study/NCT05618067", "title": "The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity", "content_text": "Not Yet Recruiting · Not applicable · Breathing Exercise Training — This study is being to see if participating in breathing exercise training and practicing this training will help with Postural tachycardia syndrome (POTS). The information may help doctors to learn more about how the different parts of people's brains communicate.", "summary": "Not Yet Recruiting · Not applicable · Breathing Exercise Training — This study is being to see if participating in breathing exercise training and practicing this training will help with Postural tachycardia syndrome (POTS). The information may help doctors to learn more about how the different part", "tags": [ "Other post-viral", "Not Yet Recruiting", "Breathing Exercise Training" ], "_osmf": { "nct_id": "NCT05618067", "status": "NOT_YET_RECRUITING", "phase": "NA", "start_date": "2028-01", "last_updated": "2026-09-16", "agents": [ "Breathing Exercise Training" ] }, "date_published": "2026-09-16T08:00:00+00:00", "date_modified": "2026-09-16T08:00:00+00:00" }, { "id": "NCT07655375:2026-09-10", "url": "https://clinicaltrials.gov/study/NCT07655375", "title": "Study Evaluating the Effect of UCB8600 on Mast Cell Activation in the Human Gut", "content_text": "Recruiting · Not applicable · Sample Collection — Study evaluating the effect of UCB8600 on mast cell activation in the human gut: IBS is a disease characterized by abdominal pain and a change in stool. Treatment is limited to an adapted life style, dietary changes and medication to lessen cramps (spasmolytica), all of which have seen limited to no…", "summary": "Recruiting · Not applicable · Sample Collection — Study evaluating the effect of UCB8600 on mast cell activation in the human gut: IBS is a disease characterized by abdominal pain and a change in stool. Treatment is limited to an adapted life style, dietary changes and medication to lessen cramps (s", "tags": [ "Other post-viral", "Recruiting", "Sample Collection" ], "_osmf": { "nct_id": "NCT07655375", "status": "RECRUITING", "phase": "NA", "start_date": "2026-08-18", "last_updated": "2026-09-10", "agents": [ "Sample Collection" ] }, "date_published": "2026-09-10T08:00:00+00:00", "date_modified": "2026-09-10T08:00:00+00:00" }, { "id": "NCT05554107:2026-09-03", "url": "https://clinicaltrials.gov/study/NCT05554107", "title": "The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome", "content_text": "Recruiting · Not applicable · Training Program — Postural orthostatic tachycardia syndrome (POTS) is a disorder of unknown origin characterized by orthostatic intolerance and increased heart rate (HR) of ≥ 30 beats/minute during orthostasis in the absence of orthostatic hypotension. In addition to the orthostatic intolerance and tachycardia, patie…", "summary": "Recruiting · Not applicable · Training Program — Postural orthostatic tachycardia syndrome (POTS) is a disorder of unknown origin characterized by orthostatic intolerance and increased heart rate (HR) of ≥ 30 beats/minute during orthostasis in the absence of orthostatic hypotension. In addition to t", "tags": [ "Other post-viral", "Recruiting", "Training Program" ], "_osmf": { "nct_id": "NCT05554107", "status": "RECRUITING", "phase": "NA", "start_date": "2022-11-02", "last_updated": "2026-09-03", "agents": [ "Training Program" ] }, "date_published": "2026-09-03T08:00:00+00:00", "date_modified": "2026-09-03T08:00:00+00:00" }, { "id": "NCT06517706:2026-09-01", "url": "https://clinicaltrials.gov/study/NCT06517706", "title": "Brain Research and Integrative Neuroscience Network for COVID-19", "content_text": "Completed · Not applicable · Combination Of Tdcs, Categorization Program — The aim of the experimental study is to investigate two interventions for the management of cognitive symptoms resulting from long COVID. Participants will be randomly assigned into two interventions. 1. Categorization Program (CP) training with active tDCS or 2. Categorization Program training with…", "summary": "Completed · Not applicable · Combination Of Tdcs, Categorization Program — The aim of the experimental study is to investigate two interventions for the management of cognitive symptoms resulting from long COVID. Participants will be randomly assigned into two interventions. 1. Categorization Progra", "tags": [ "Other post-viral", "Completed", "Combination Of Tdcs", "Categorization Program" ], "_osmf": { "nct_id": "NCT06517706", "status": "COMPLETED", "phase": "NA", "start_date": "2024-11-15", "last_updated": "2026-09-01", "agents": [ "Combination Of Tdcs", "Categorization Program" ] }, "date_published": "2026-09-01T08:00:00+00:00", "date_modified": "2026-09-01T08:00:00+00:00" }, { "id": "NCT04308278:2026-08-31", "url": "https://clinicaltrials.gov/study/NCT04308278", "title": "Study to Evaluate the Efficacy of 2LEBV® and 2LXFS® on Asthenia in Patients With an Epstein-Barr Virus Infection", "content_text": "Recruiting · Phase 4 · 2Lebv® / 2Lxfs® — Worldwide, 95% of adults are infected with Epstein-Barr Virus (EBV). These infections may cause different diseases. In most cases, EBV infection is asymptomatic because of a highly effective host immune response. Some individuals develop infectious mononucleosis (a self-limiting lymphoproliferative …", "summary": "Recruiting · Phase 4 · 2Lebv® / 2Lxfs® — Worldwide, 95% of adults are infected with Epstein-Barr Virus (EBV). These infections may cause different diseases. In most cases, EBV infection is asymptomatic because of a highly effective host immune response. Some individuals develop infectious mononucleo", "tags": [ "Other post-viral", "Recruiting", "2Lebv® / 2Lxfs®" ], "_osmf": { "nct_id": "NCT04308278", "status": "RECRUITING", "phase": "PHASE4", "start_date": "2021-01-22", "last_updated": "2026-08-31", "agents": [ "2Lebv® / 2Lxfs®" ] }, "date_published": "2026-08-31T08:00:00+00:00", "date_modified": "2026-08-31T08:00:00+00:00" }, { "id": "NCT05350774:2026-08-26", "url": "https://clinicaltrials.gov/study/NCT05350774", "title": "Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2", "content_text": "Enrolling By Invitation · Phase 2 · Iv Normal Saline, Iv Immunoglobulin — Background: COVID-19 can cause problems in different parts of the body. For most people, it causes fevers or trouble breathing. Some people might not recover all the way. Researchers want to see if a treatment can help with people who have recovered from COVID-19 but still have symptoms (\"Long COVID…", "summary": "Enrolling By Invitation · Phase 2 · Iv Normal Saline, Iv Immunoglobulin — Background: COVID-19 can cause problems in different parts of the body. For most people, it causes fevers or trouble breathing. Some people might not recover all the way. Researchers want to see if a treatment can help with pe", "tags": [ "Other post-viral", "Enrolling By Invitation", "Iv Normal Saline", "Iv Immunoglobulin" ], "_osmf": { "nct_id": "NCT05350774", "status": "ENROLLING_BY_INVITATION", "phase": "PHASE2", "start_date": "2023-07-10", "last_updated": "2026-08-26", "agents": [ "Iv Normal Saline", "Iv Immunoglobulin" ] }, "date_published": "2026-08-26T08:00:00+00:00", "date_modified": "2026-08-26T08:00:00+00:00" }, { "id": "NCT07757555:2026-08-12", "url": "https://clinicaltrials.gov/study/NCT07757555", "title": "Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial", "content_text": "Not Yet Recruiting · Early phase 1 · Guanfacine, Cromolyn Sodium — The goal of this clinical trial is to learn whether guanfacine or cromolyn sodium can improve symptoms and physical functioning in adults with Postural Orthostatic Tachycardia Syndrome (POTS). Both medications are FDA-approved for other conditions but are investigational for the treatment of POTS. T…", "summary": "Not Yet Recruiting · Early phase 1 · Guanfacine, Cromolyn Sodium — The goal of this clinical trial is to learn whether guanfacine or cromolyn sodium can improve symptoms and physical functioning in adults with Postural Orthostatic Tachycardia Syndrome (POTS). Both medications are FDA-approved for ot", "tags": [ "Other post-viral", "Not Yet Recruiting", "Guanfacine", "Cromolyn Sodium" ], "_osmf": { "nct_id": "NCT07757555", "status": "NOT_YET_RECRUITING", "phase": "EARLY_PHASE1", "start_date": "2026-08-15", "last_updated": "2026-08-12", "agents": [ "Guanfacine", "Cromolyn Sodium" ] }, "date_published": "2026-08-12T08:00:00+00:00", "date_modified": "2026-08-12T08:00:00+00:00" }, { "id": "NCT05400174:2026-08-07", "url": "https://clinicaltrials.gov/study/NCT05400174", "title": "Blood Pressure Effects on Cognition and Brain Blood Flow in PD", "content_text": "Recruiting · Not applicable · Tilt Table — Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing. About one-third of peopl…", "summary": "Recruiting · Not applicable · Tilt Table — Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (", "tags": [ "Other post-viral", "Recruiting", "Tilt Table" ], "_osmf": { "nct_id": "NCT05400174", "status": "RECRUITING", "phase": "NA", "start_date": "2021-12-14", "last_updated": "2026-08-07", "agents": [ "Tilt Table" ] }, "date_published": "2026-08-07T08:00:00+00:00", "date_modified": "2026-08-07T08:00:00+00:00" }, { "id": "NCT05043051:2026-07-29", "url": "https://clinicaltrials.gov/study/NCT05043051", "title": "Autoimmune Basis for Postural Tachycardia Syndrome", "content_text": "Completed · Not applicable · Vagal Stimulation — The purpose of this study is to test the hypothesis that an antibody-mediated autoimmune reaction will cause symptoms of autonomic dysfunction in some patients with postural tachycardia syndrome (POTS). The investigators further hypothesize that electrical stimulation of the vagus nerve will improve…", "summary": "Completed · Not applicable · Vagal Stimulation — The purpose of this study is to test the hypothesis that an antibody-mediated autoimmune reaction will cause symptoms of autonomic dysfunction in some patients with postural tachycardia syndrome (POTS). The investigators further hypothesize that elect", "tags": [ "Other post-viral", "Completed", "Vagal Stimulation" ], "_osmf": { "nct_id": "NCT05043051", "status": "COMPLETED", "phase": "NA", "start_date": "2022-01-14", "last_updated": "2026-07-29", "agents": [ "Vagal Stimulation" ] }, "date_published": "2026-07-29T08:00:00+00:00", "date_modified": "2026-07-29T08:00:00+00:00" }, { "id": "NCT06593600:2026-07-21", "url": "https://clinicaltrials.gov/study/NCT06593600", "title": "Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)", "content_text": "Completed · Phase 2 · Regn7544 — This study is researching an experimental drug called REGN7544 (called \"study drug\"). The study is focused on participants with POTS. The aim of the study is to see how safe, tolerable, and effective the study drug is. The study is looking at several other research questions, including: * How the st…", "summary": "Completed · Phase 2 · Regn7544 — This study is researching an experimental drug called REGN7544 (called \"study drug\"). The study is focused on participants with POTS. The aim of the study is to see how safe, tolerable, and effective the study drug is. The study is looking at several other research q", "tags": [ "Other post-viral", "Completed", "Regn7544" ], "_osmf": { "nct_id": "NCT06593600", "status": "COMPLETED", "phase": "PHASE2", "start_date": "2024-11-13", "last_updated": "2026-07-21", "agents": [ "Regn7544" ] }, "date_published": "2026-07-21T08:00:00+00:00", "date_modified": "2026-07-21T08:00:00+00:00" }, { "id": "NCT03124355:2026-07-13", "url": "https://clinicaltrials.gov/study/NCT03124355", "title": "Vagal Stimulation in POTS", "content_text": "Active Not Recruiting · Phase 1 · Pyridostigmine Pill, Galantamine Pill, Vagal Stimulation — The purpose of this study is to investigate how the electrical stimulation of a nerve in the skin of the earlobe (transcutaneous vagal nerve stimulation), alone or in combination with two medications (galantamine and pyridostigmine), affects the way the autonomic (involuntary) nervous system control…", "summary": "Active Not Recruiting · Phase 1 · Pyridostigmine Pill, Galantamine Pill, Vagal Stimulation — The purpose of this study is to investigate how the electrical stimulation of a nerve in the skin of the earlobe (transcutaneous vagal nerve stimulation), alone or in combination with two medications (galant", "tags": [ "Other post-viral", "Active Not Recruiting", "Pyridostigmine Pill", "Galantamine Pill", "Vagal Stimulation" ], "_osmf": { "nct_id": "NCT03124355", "status": "ACTIVE_NOT_RECRUITING", "phase": "PHASE1", "start_date": "2017-09-30", "last_updated": "2026-07-13", "agents": [ "Pyridostigmine Pill", "Galantamine Pill", "Vagal Stimulation" ] }, "date_published": "2026-07-13T08:00:00+00:00", "date_modified": "2026-07-13T08:00:00+00:00" }, { "id": "NCT07675876:2026-07-01", "url": "https://clinicaltrials.gov/study/NCT07675876", "title": "Inhaled Cromolyn Sodium in Patients With Locally Advanced Lung Cancer", "content_text": "Not Yet Recruiting · Phase 1 · Cromolyn Sodium — Brief Summary This prospective, open-label pilot study is designed to evaluate the safety, tolerability, feasibility, and preliminary clinical activity of inhaled cromolyn sodium administered by dry powder inhalation in participants with locally advanced lung cancer. Cromolyn sodium is an FDA-approv…", "summary": "Not Yet Recruiting · Phase 1 · Cromolyn Sodium — Brief Summary This prospective, open-label pilot study is designed to evaluate the safety, tolerability, feasibility, and preliminary clinical activity of inhaled cromolyn sodium administered by dry powder inhalation in participants with locally advan", "tags": [ "Other post-viral", "Not Yet Recruiting", "Cromolyn Sodium" ], "_osmf": { "nct_id": "NCT07675876", "status": "NOT_YET_RECRUITING", "phase": "PHASE1", "start_date": "2026-08", "last_updated": "2026-07-01", "agents": [ "Cromolyn Sodium" ] }, "date_published": "2026-07-01T08:00:00+00:00", "date_modified": "2026-07-01T08:00:00+00:00" }, { "id": "NCT04827992:2026-06-24", "url": "https://clinicaltrials.gov/study/NCT04827992", "title": "Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain", "content_text": "Completed · Not applicable · Cannabis, Prescription Opioid Taper Support — This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain intensity and interference when added to a 24-week behavioral intervention…", "summary": "Completed · Not applicable · Cannabis, Prescription Opioid Taper Support — This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain", "tags": [ "Other post-viral", "Completed", "Cannabis", "Prescription Opioid Taper Support" ], "_osmf": { "nct_id": "NCT04827992", "status": "COMPLETED", "phase": "NA", "start_date": "2021-08-23", "last_updated": "2026-06-24", "agents": [ "Cannabis", "Prescription Opioid Taper Support" ] }, "date_published": "2026-06-24T08:00:00+00:00", "date_modified": "2026-06-24T08:00:00+00:00" }, { "id": "NCT05947136:2026-06-11", "url": "https://clinicaltrials.gov/study/NCT05947136", "title": "PASCA-MM Study. Impact of the PASCA (PArcours de Santé au Cours du CAncer) Program on Complications Associated With Multiple Myeloma and/or Its Treatments in the Context of a First Hematopoietic Stem Cell Autograft, in Adults Aged 18 to 70.", "content_text": "Recruiting · Not applicable · Interpretation Of The Results From The Detection Visit, Explaining Detection Results And Referrals To The Patient, Early Medical Care Through The Network — This is a prospective, multicentre, phase III, randomised, controlled intervention study. Two groups of patients with equal numbers will be studied and each patient will be allocated to one of the two groups described below by randomisation (ratio 1:1). Each patient will be allocated to one of the t…", "summary": "Recruiting · Not applicable · Interpretation Of The Results From The Detection Visit, Explaining Detection Results And Referrals To The Patient, Early Medical Care Through The Network — This is a prospective, multicentre, phase III, randomised, controlled intervention study. Two groups of patients w", "tags": [ "Other post-viral", "Recruiting", "Interpretation Of The Results From The Detection Visit", "Explaining Detection Results And Referrals To The Patient", "Early Medical Care Through The Network" ], "_osmf": { "nct_id": "NCT05947136", "status": "RECRUITING", "phase": "NA", "start_date": "2024-01-19", "last_updated": "2026-06-11", "agents": [ "Interpretation Of The Results From The Detection Visit", "Explaining Detection Results And Referrals To The Patient", "Early Medical Care Through The Network" ] }, "date_published": "2026-06-11T08:00:00+00:00", "date_modified": "2026-06-11T08:00:00+00:00" }, { "id": "NCT07600320:2026-05-20", "url": "https://clinicaltrials.gov/study/NCT07600320", "title": "Fareon Open Label Device Clinical Trial", "content_text": "Not Yet Recruiting · Not applicable · Fareon Device — The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis (ME/CFS), and other neurodegenerative diagnoses including but not limit…", "summary": "Not Yet Recruiting · Not applicable · Fareon Device — The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis (ME/CFS), and oth", "tags": [ "Other post-viral", "Not Yet Recruiting", "Fareon Device" ], "_osmf": { "nct_id": "NCT07600320", "status": "NOT_YET_RECRUITING", "phase": "NA", "start_date": "2026-05-01", "last_updated": "2026-05-20", "agents": [ "Fareon Device" ] }, "date_published": "2026-05-20T08:00:00+00:00", "date_modified": "2026-05-20T08:00:00+00:00" }, { "id": "NCT07585513:2026-05-13", "url": "https://clinicaltrials.gov/study/NCT07585513", "title": "Beta-3 Enhanced Autonomic Therapy for POTS", "content_text": "Not Yet Recruiting · Phase 2 · Mirabegron — The study will test the hypothesis that mirabegron is more effective than a placebo in alleviating postural orthostatic tachycardia (POTS) symptoms.", "summary": "Not Yet Recruiting · Phase 2 · Mirabegron — The study will test the hypothesis that mirabegron is more effective than a placebo in alleviating postural orthostatic tachycardia (POTS) symptoms.", "tags": [ "Other post-viral", "Not Yet Recruiting", "Mirabegron" ], "_osmf": { "nct_id": "NCT07585513", "status": "NOT_YET_RECRUITING", "phase": "PHASE2", "start_date": "2026-05", "last_updated": "2026-05-13", "agents": [ "Mirabegron" ] }, "date_published": "2026-05-13T08:00:00+00:00", "date_modified": "2026-05-13T08:00:00+00:00" }, { "id": "NCT07567274:2026-05-13", "url": "https://clinicaltrials.gov/study/NCT07567274", "title": "DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury", "content_text": "Enrolling By Invitation · Phase 2 · Dmso-Based Otic Solution With Betahistine, Dexamethasone, And Lidocaine, N-Acetylcysteine (NAC) — The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to long-COVID (post-acute sequelae of SARS-CoV-2) or post-COVID-19 vaccine injury. Participants have bothersome tinnitus that has not impro…", "summary": "Enrolling By Invitation · Phase 2 · Dmso-Based Otic Solution With Betahistine, Dexamethasone, And Lidocaine, N-Acetylcysteine (NAC) — The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to lo", "tags": [ "Other post-viral", "Enrolling By Invitation", "Dmso-Based Otic Solution With Betahistine, Dexamethasone, And Lidocaine", "N-Acetylcysteine (NAC)" ], "_osmf": { "nct_id": "NCT07567274", "status": "ENROLLING_BY_INVITATION", "phase": "PHASE2", "start_date": "2026-05-15", "last_updated": "2026-05-13", "agents": [ "Dmso-Based Otic Solution With Betahistine, Dexamethasone, And Lidocaine", "N-Acetylcysteine (NAC)" ] }, "date_published": "2026-05-13T08:00:00+00:00", "date_modified": "2026-05-13T08:00:00+00:00" }, { "id": "NCT07579026:2026-05-11", "url": "https://clinicaltrials.gov/study/NCT07579026", "title": "Effects of Breathing Retraining Exercises in Pregnant Females With Postural Orthostatic Tachycardia Syndrome.", "content_text": "Recruiting · Not applicable · Diaphragmatic Breathing Exercise — Postural orthostatic tachycardia POTS is characterized by excessive increase in heart rate when moving from lying to standing position, often accompanied by symptoms such as dizziness, fatigue, brain fog, lightheadedness, rapid heartbeat and palpitation.it most commonly effects the females of reprod…", "summary": "Recruiting · Not applicable · Diaphragmatic Breathing Exercise — Postural orthostatic tachycardia POTS is characterized by excessive increase in heart rate when moving from lying to standing position, often accompanied by symptoms such as dizziness, fatigue, brain fog, lightheadedness, rapid heartbe", "tags": [ "Other post-viral", "Recruiting", "Diaphragmatic Breathing Exercise" ], "_osmf": { "nct_id": "NCT07579026", "status": "RECRUITING", "phase": "NA", "start_date": "2025-08-31", "last_updated": "2026-05-11", "agents": [ "Diaphragmatic Breathing Exercise" ] }, "date_published": "2026-05-11T08:00:00+00:00", "date_modified": "2026-05-11T08:00:00+00:00" }, { "id": "NCT07409363:2026-05-11", "url": "https://clinicaltrials.gov/study/NCT07409363", "title": "Non-invasive Vagus Nerve Stimulation for Chronic Musculoskeletal Pain", "content_text": "Not Yet Recruiting · Not applicable · Active Vagus Nerve Stimulation — Chronic musculoskeletal (MSK) pain affects an estimated 20-33% of the global population and is frequently associated with autonomic nervous system dysfunction, characterised by symptoms such as orthostatic intolerance, palpitations, gastrointestinal dysmotility, and fatigue. Conventional treatments …", "summary": "Not Yet Recruiting · Not applicable · Active Vagus Nerve Stimulation — Chronic musculoskeletal (MSK) pain affects an estimated 20-33% of the global population and is frequently associated with autonomic nervous system dysfunction, characterised by symptoms such as orthostatic intolerance, palpitatio", "tags": [ "Other post-viral", "Not Yet Recruiting", "Active Vagus Nerve Stimulation" ], "_osmf": { "nct_id": "NCT07409363", "status": "NOT_YET_RECRUITING", "phase": "NA", "start_date": "2026-05-14", "last_updated": "2026-05-11", "agents": [ "Active Vagus Nerve Stimulation" ] }, "date_published": "2026-05-11T08:00:00+00:00", "date_modified": "2026-05-11T08:00:00+00:00" }, { "id": "NCT06208163:2026-05-08", "url": "https://clinicaltrials.gov/study/NCT06208163", "title": "The Effects of Chiropractic in a Population With High Central Adiposity", "content_text": "Completed · Not applicable · Chiropractic — Since 1980, the global prevalence of obesity, commonly defined as a body mass index (BMI) of 30 or higher, has doubled. Importantly, high levels of central adiposity (i.e., abdominal fat) is associated with numerous PNI-related sequelae, including increased levels of psychological distress, cognitiv…", "summary": "Completed · Not applicable · Chiropractic — Since 1980, the global prevalence of obesity, commonly defined as a body mass index (BMI) of 30 or higher, has doubled. Importantly, high levels of central adiposity (i.e., abdominal fat) is associated with numerous PNI-related sequelae, including increase", "tags": [ "Other post-viral", "Completed", "Chiropractic" ], "_osmf": { "nct_id": "NCT06208163", "status": "COMPLETED", "phase": "NA", "start_date": "2024-11-11", "last_updated": "2026-05-08", "agents": [ "Chiropractic" ] }, "date_published": "2026-05-08T08:00:00+00:00", "date_modified": "2026-05-08T08:00:00+00:00" }, { "id": "NCT05924646:2026-05-07", "url": "https://clinicaltrials.gov/study/NCT05924646", "title": "CAlgary SAlt for POTS", "content_text": "Recruiting · Not applicable · Microcystalline Cellulose Capsules — Many patients with postural orthostatic tachycardia syndrome (POTS) have decreased plasma volume. Current POTS guidelines recommend \\~10 g of salt and 2-3 L of fluid per day. Despite this recommendation, there is no long term data evaluating the use of salt in POTS. This randomized, placebo-controll…", "summary": "Recruiting · Not applicable · Microcystalline Cellulose Capsules — Many patients with postural orthostatic tachycardia syndrome (POTS) have decreased plasma volume. Current POTS guidelines recommend \\~10 g of salt and 2-3 L of fluid per day. Despite this recommendation, there is no long term data ev", "tags": [ "Other post-viral", "Recruiting", "Microcystalline Cellulose Capsules" ], "_osmf": { "nct_id": "NCT05924646", "status": "RECRUITING", "phase": "NA", "start_date": "2024-05-07", "last_updated": "2026-05-07", "agents": [ "Microcystalline Cellulose Capsules" ] }, "date_published": "2026-05-07T08:00:00+00:00", "date_modified": "2026-05-07T08:00:00+00:00" }, { "id": "NCT05914649:2026-05-07", "url": "https://clinicaltrials.gov/study/NCT05914649", "title": "NC Testing in LC & POTS", "content_text": "Recruiting · Not applicable · Iv Normal Saline — Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or \"Long COVID\") experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive function in patients with POTS and Long COVID compared …", "summary": "Recruiting · Not applicable · Iv Normal Saline — Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or \"Long COVID\") experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive functi", "tags": [ "Other post-viral", "Recruiting", "Iv Normal Saline" ], "_osmf": { "nct_id": "NCT05914649", "status": "RECRUITING", "phase": "NA", "start_date": "2024-09-19", "last_updated": "2026-05-07", "agents": [ "Iv Normal Saline" ] }, "date_published": "2026-05-07T08:00:00+00:00", "date_modified": "2026-05-07T08:00:00+00:00" }, { "id": "NCT04881318:2026-05-07", "url": "https://clinicaltrials.gov/study/NCT04881318", "title": "Compression Garments in the Community With POTS", "content_text": "Recruiting · Not applicable · Waist-High Compression Tights, Abdominal Compression Garments, Medications That Modulate Heart Rate And Blood Pressure — Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that particip…", "summary": "Recruiting · Not applicable · Waist-High Compression Tights, Abdominal Compression Garments, Medications That Modulate Heart Rate And Blood Pressure — Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept", "tags": [ "Other post-viral", "Recruiting", "Waist-High Compression Tights", "Abdominal Compression Garments", "Medications That Modulate Heart Rate And Blood Pressure" ], "_osmf": { "nct_id": "NCT04881318", "status": "RECRUITING", "phase": "NA", "start_date": "2021-05-17", "last_updated": "2026-05-07", "agents": [ "Waist-High Compression Tights", "Abdominal Compression Garments", "Medications That Modulate Heart Rate And Blood Pressure" ] }, "date_published": "2026-05-07T08:00:00+00:00", "date_modified": "2026-05-07T08:00:00+00:00" }, { "id": "NCT04271878:2026-05-07", "url": "https://clinicaltrials.gov/study/NCT04271878", "title": "Hypercapnia and Orthostatic Tolerance in Postural Orthostatic Tachycardia Syndrome", "content_text": "Recruiting · Not applicable · Respiract™ System — The mechanism behind postural orthostatic tachycardia syndrome (POTS) involves many causes including a sympathetic nervous system problem. Blood gases, like carbon dioxide (CO2), have an important effect on sympathetic activation. The purpose of this research study is to determine if higher CO2 leve…", "summary": "Recruiting · Not applicable · Respiract™ System — The mechanism behind postural orthostatic tachycardia syndrome (POTS) involves many causes including a sympathetic nervous system problem. Blood gases, like carbon dioxide (CO2), have an important effect on sympathetic activation. The purpose of this", "tags": [ "Other post-viral", "Recruiting", "Respiract™ System" ], "_osmf": { "nct_id": "NCT04271878", "status": "RECRUITING", "phase": "NA", "start_date": "2022-02-02", "last_updated": "2026-05-07", "agents": [ "Respiract™ System" ] }, "date_published": "2026-05-07T08:00:00+00:00", "date_modified": "2026-05-07T08:00:00+00:00" } ] }