https://research.opensourcemed.info/clinical_trials.htmlClinicalTrials.gov records for All tracked conditions that were newly registered or updated, as tracked by the Open Source Medicine Foundation research tracker. The 30 most recently updated trials, newest first.enFri, 09 Oct 2026 11:21:14 +0000OSMF build_condition_feeds.py1440https://opensourcemed.info/favicon.pnghttps://research.opensourcemed.info/clinical_trials.htmlhttps://clinicaltrials.gov/study/NCT07546539NCT07546539:2026-10-08Thu, 08 Oct 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Photobiomodulation — The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS). The study will include adults aged 18-60 years diagnosed with chronic fatigue syndrome. The main…https://clinicaltrials.gov/study/NCT07388550NCT07388550:2026-10-08Thu, 08 Oct 2026 08:00:00 +0000All conditionsNot Yet RecruitingNot Yet Recruiting · Phase 1 · Keytruda — Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from an acute COVID-19 infection may continue to have symptoms that persist for months or years. These can include neurological symptoms, such as headaches, loss of taste or smell, dizziness, or trouble walking. Pembro…https://clinicaltrials.gov/study/NCT07285473NCT07285473:2026-10-08Thu, 08 Oct 2026 08:00:00 +0000All conditionsNot Yet RecruitingNot Yet Recruiting · Phase 2 · Low-Dose Naltrexone (LDN) — This exploratory clinical trial tests low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A remote trial approach is used, with eligibility open to the state of Alabama.https://clinicaltrials.gov/study/NCT06822179NCT06822179:2026-10-08Thu, 08 Oct 2026 08:00:00 +0000All conditionsCompletedCompleted · Phase 2 · Personalised Exercise Program — The goal of this clinical trial is to evaluate whether a 12-week tele-rehabilitation programme roduces medium-term improvements in self-management, fatigue and quality of life in patients affected by persistent COVID. The main questions it aims to answer are: * Will a multimodal program (exercise wi…https://clinicaltrials.gov/study/NCT06766825NCT06766825:2026-10-08Thu, 08 Oct 2026 08:00:00 +0000All conditionsCompletedCompleted · Phase 2 · Plitidepsin 1.5 Mg/Day — The study aims to prove that plitidepsin could be an efficacious, safe, and well-tolerated therapy for PCC. To this end, we will perform a randomized, double-blind study comparing the clinical and laboratory benefits of plitidepsin vs. placebo in 90 subjects with moderate to severe functional disabi…https://clinicaltrials.gov/study/NCT05874037NCT05874037:2026-10-07Wed, 07 Oct 2026 08:00:00 +0000All conditionsCompletedCompleted · Phase 2 · Fluvoxamine — This clinical trial aims to test the effects of fluvoxamine as a treatment for Long COVID. Fluvoxamine is an FDA approved SSRI for Obsessive Compulsive Disorder (OCD), that has already had success in preventing hospitalization in patients with COVID-19 (STOP COVID and TOGETHER trials). This trial is…https://clinicaltrials.gov/study/NCT07661862NCT07661862:2026-10-06Tue, 06 Oct 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Perceive-Outreach Disease Management Program — Some people who had COVID-19 continue to have symptoms for weeks, months, or even years after their infection. This is often called "Long COVID" or Post-Acute Sequelae of SARS-CoV-2 (PASC). For some people, Long COVID can affect the heart and lungs, making it harder to exercise or carry out daily ac…https://clinicaltrials.gov/study/NCT06928272NCT06928272:2026-10-06Tue, 06 Oct 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 3 · Pirfenidone, Upadacitinib — The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, involving adult participants from Brazil, Canada, Italy, South Africa, Uganda, the United States, and Zambia. To qualify, participants must have had Covid-19 and experienced Long Covid symptoms for at…https://clinicaltrials.gov/study/NCT06404073NCT06404073:2026-10-06Tue, 06 Oct 2026 08:00:00 +0000All conditionsCompletedCompleted · Not applicable · Structured Pacing — This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. This…https://clinicaltrials.gov/study/NCT07398508NCT07398508:2026-10-05Mon, 05 Oct 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 1 · Droxidopa Oral Product — This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of Menkes disease through early Copper Histidinate treatment. The investigat…https://clinicaltrials.gov/study/NCT05493605NCT05493605:2026-10-01Thu, 01 Oct 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Delivery Of A Long-Term Holter 21 Days Or Placement Of An Implantable Holter From The Outset So Syncope — Heart damage by copper accumulation has been reported in Wilson's Disease. However, the disease epidemiology is still poorly understood. A number of studies on pediatric populations have not shown any significant cardiac involvement apart from early dysautonomia. This could suggest that the clinical…https://clinicaltrials.gov/study/NCT07621588NCT07621588:2026-09-29Tue, 29 Sep 2026 08:00:00 +0000All conditionsCompletedCompleted · Not applicable · Diaphragmatic Electrostimulation Using Kots Currents, Diaphragmatic Breathing Exercises — This study will evaluate the effects of diaphragmatic breathing exercises combined with diaphragmatic electrostimulation using KOTS currents in patients with Long COVID. Participants will be randomly assigned to one of two groups. The control group will perform diaphragmatic breathing exercises, whi…https://clinicaltrials.gov/study/NCT07468604NCT07468604:2026-09-29Tue, 29 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 4 · 5 Ml Of 0.25% Bupivacaine With Epinephrine — Post-COVID Condition (PCC) affects roughly 2.1 million Canadians, carrying an annual economic burden of CAD $7.8-50.6 billion. It presents across multiple organ systems with symptoms including fatigue, brain fog, palpitations, and orthostatic intolerance, at an annual cost of CAD $1,675-$7,340 per c…https://clinicaltrials.gov/study/NCT07021794NCT07021794:2026-09-29Tue, 29 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 2 · Sipavibart — This placebo-controlled, randomized, blinded, two-arm phase II study will test the safety and potential efficacy of the targeted mAb, Sipavibart (formerly AZD3152) in patients with Long COVID.https://clinicaltrials.gov/study/NCT06928116NCT06928116:2026-09-28Mon, 28 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Heat Therapy, Walking — Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restor…https://clinicaltrials.gov/study/NCT07842302NCT07842302:2026-09-25Fri, 25 Sep 2026 08:00:00 +0000All conditionsNot Yet RecruitingNot Yet Recruiting · Not applicable · Tms, Tdcs — Multiple Sclerosis (MS) is a chronic neurological disease impacting 2.8 million individuals globally, with fatigue being its most debilitating symptom, reported by 75% of patients. Despite its prevalence, the pathophysiology of MS-related fatigue remains poorly understood, and current pharmacologica…https://clinicaltrials.gov/study/NCT07005921NCT07005921:2026-09-25Fri, 25 Sep 2026 08:00:00 +0000All conditionsCompletedCompleted · Not applicable · Qeeg-Neurofeedback — The pandemic has highlighted social, economic, educational, and political issues that have affected the health and quality of life of millions of Brazilians. Currently, attention and memory impairment remains predominant among the cognitive symptoms of Coronavirus observed in adults. The persistance…https://clinicaltrials.gov/study/NCT06631287NCT06631287:2026-09-25Fri, 25 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 3 · Baricitinib — The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of breathlessness on daily activities, post-COVID-19 symptom burden, and biomark…https://clinicaltrials.gov/study/NCT07837804NCT07837804:2026-09-24Thu, 24 Sep 2026 08:00:00 +0000All conditionsNot Yet RecruitingNot Yet Recruiting · Not applicable · Bilateral Sequential Stellate Ganglion Block — RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing. The study has two parts. In the first part, patients with POTS and healthy volunteer…https://clinicaltrials.gov/study/NCT07123727NCT07123727:2026-09-24Thu, 24 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 2 · Anktiva — This study will examine the safety and effectiveness of Anktiva in treating patients with Long COVID-19 which is defined as persistent symptoms of a COVID-19 infection that remain after the infection is over.https://clinicaltrials.gov/study/NCT04137757NCT04137757:2026-09-24Thu, 24 Sep 2026 08:00:00 +0000All conditionsActive Not RecruitingActive Not Recruiting · Not applicable · Lower Body Negative Pressure — Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance in the United States. This is a disabling disorder characterized by an excessive increase in heart rate upon standing that is accompanied by symptoms such as dizziness and fatigue. One of the most…https://clinicaltrials.gov/study/NCT06847191NCT06847191:2026-09-22Tue, 22 Sep 2026 08:00:00 +0000All conditionsCompletedCompleted · Phase 2 · Ne3107 — Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infection. This study aims to evaluate the effects of NE3107 on several neurological symptoms reported in people with Long COVID including difficulty concentrating or remembering things ("brain fog") and fa…https://clinicaltrials.gov/study/NCT06739720NCT06739720:2026-09-21Mon, 21 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 2 · Lingzhi Capsule — The goal of this clinical trial is to test if a Lingzhi supplement (CP003) helps people with chronic fatigue or post-COVID fatigue feel better. It will also check if the supplement is safe to use. The main questions it aims to answer are: Does the Lingzhi supplement reduce fatigue symptoms? Is it sa…https://clinicaltrials.gov/study/NCT06721949NCT06721949:2026-09-18Fri, 18 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Phase 2 · Taurine — The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to experience persistent and debilitating symptoms long after the initial SARS…https://clinicaltrials.gov/study/NCT06472622NCT06472622:2026-09-18Fri, 18 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Early phase 1 · Thermal Pain Stimulation, Physical Effort Stimulation — Background: The way the brain processes rewards and punishments may play a role in some disorders of the nervous system. People with chronic overlapping pain conditions (such as myalgic encephalomyelitis/chronic fatigue syndrome \[ME/CFS\]) may have heightened responses to unpleasant, punishing sens…https://clinicaltrials.gov/study/NCT06821087NCT06821087:2026-09-17Thu, 17 Sep 2026 08:00:00 +0000All conditionsCompletedCompleted · Phase 2 · Ketamine Only — Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms of Long COVID, especially fatigue and problems with thinking clearly (often called "brain fog"). Long COVID is a condition that affects people even after they have recovered from COVID-19, causing ongoi…https://clinicaltrials.gov/study/NCT05618067NCT05618067:2026-09-16Wed, 16 Sep 2026 08:00:00 +0000All conditionsNot Yet RecruitingNot Yet Recruiting · Not applicable · Breathing Exercise Training — This study is being to see if participating in breathing exercise training and practicing this training will help with Postural tachycardia syndrome (POTS). The information may help doctors to learn more about how the different parts of people's brains communicate.https://clinicaltrials.gov/study/NCT05851859NCT05851859:2026-09-14Mon, 14 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Cardiac Coherence — Despite the controversy, on October 6, 2021, the World Health Organization (WHO) recognized Long Coronavirus disease (COVID) by officially defining it: " symptoms appeared 3 months after the onset of the primary infection by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), persistin…https://clinicaltrials.gov/study/NCT07655375NCT07655375:2026-09-10Thu, 10 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Sample Collection — Study evaluating the effect of UCB8600 on mast cell activation in the human gut: IBS is a disease characterized by abdominal pain and a change in stool. Treatment is limited to an adapted life style, dietary changes and medication to lessen cramps (spasmolytica), all of which have seen limited to no…https://clinicaltrials.gov/study/NCT06933173NCT06933173:2026-09-09Wed, 09 Sep 2026 08:00:00 +0000All conditionsRecruitingRecruiting · Not applicable · Dynamic Neural Retraining System — We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC). Our team recognizes that ME/CFS and Long COVID are serious, debilitating, biomedical conditions. ME/CFS can affect many different parts of …