{ "id": "2026-W46", "year": 2026, "week": 46, "week_monday": "2026-11-09", "week_sunday": "2026-11-15", "asof": "2026-11-11", "window_start": "2026-11-05", "window_end": "2026-11-11", "window_days": 7, "widened": false, "strict_study_count": 30, "strict_trial_count": 13, "study_count": 30, "trial_count": 13, "studies": { "long-covid": [ { "pmid": "42996569", "title": "Treatment strategies in pancreatic adenosquamous carcinoma: a systematic review and pooled analysis of individual cases.", "journal": "Journal of gastrointestinal oncology", "pub_date": "2026-11-08", "authors": "Gao, Xiang Yu, Ganatra, Nency, Abdelhakeem, Ahmed, Tran, Nugyen et al.", "excerpt": "Pancreatic adenosquamous carcinoma (PASC) is a rare 1-4% of all pancreatic cancers and an aggressive pancreatic malignancy characterized by mixed adenocarcinoma and squamous histologies. Even after surgical intervention, patients with PASC have a lower median overall survival (mOS) than those with the more prevalent pancreatic ductal adenocarcinoma (PDAC).", "url": "https://pubmed.ncbi.nlm.nih.gov/42996569/", "also": [] }, { "pmid": "42995851", "title": "Persistently activated virus-specific CD8 T cells indicate antigen-driven immune aberrations in long COVID.", "journal": "bioRxiv : the preprint server for biology", "pub_date": "2026-11-08", "authors": "Painter, Mark M, Reeg, David B, Douek, Naomi R, Gray-Gaillard, Sophie L et al.", "excerpt": "Long COVID (LC) affects millions of people worldwide, yet its driving mechanisms remain incompletely defined and no treatment has been approved. Persistence of SARS-CoV-2 and reactivation of herpesviruses have been implicated in LC, but direct detection of these viral antigens in blood and tissues has been challenging.", "url": "https://pubmed.ncbi.nlm.nih.gov/42995851/", "also": [] }, { "pmid": "42998216", "title": "Long COVID: A Modified Delphi Consensus on Definition, Burden, Diagnosis and Management in Southeast Asia.", "journal": "Pulmonary therapy", "pub_date": "2026-11-08", "authors": "Burhan, Erlina, Chew, Huck Chin, Isbaniah, Fathiyah, Jogulu, Sathya Rao et al.", "excerpt": "Long COVID is a heterogeneous post-infectious condition following acute severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection. Ongoing uncertainty around its definition, burden, diagnosis and management complicates clinical recognition and care in Southeast Asia.", "url": "https://pubmed.ncbi.nlm.nih.gov/42998216/", "also": [] }, { "pmid": "42996642", "title": "Implementation effectiveness of the Long COVID and Fatiguing Illnesses Recovery Program (LC&FIRP): a multimodal Extension for Community Healthcare Outcomes (ECHO) model for clinician learning.", "journal": "Frontiers in health services", "pub_date": "2026-11-08", "authors": "Zuber, Alexandra, Rothwell, Jonathan T, Godino, Job G, Samaniego, Jane C et al.", "excerpt": "Long COVID and other infection-associated chronic conditions (IACC) present management challenges for primary care clinicians and often require patient access to multidisciplinary specialists. To strengthen primary care capacity, the Long COVID and Fatiguing Illnesses Recovery Program (LC&FIRP) implemented a multi-modal learning model combining Extension for Community Healthcare Outcomes (ECHO) case-based learning...", "url": "https://pubmed.ncbi.nlm.nih.gov/42996642/", "also": [] }, { "pmid": "42998183", "title": "Development and initial content validation of the Vienna post-exertional malaise questionnaire: an iterative mixed-methods study.", "journal": "Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation", "pub_date": "2026-11-08", "authors": "Pimminger, Theresa, Ahrens-Schwabe, Annika, Fragner, Tobias, Brandl, Tobias et al.", "excerpt": "Post-exertional malaise (PEM) is a multidimensional exertion-response pattern involving diverse triggers, variable onset, and prolonged recovery. This study developed and content-validated the Vienna Post-Exertional Malaise (VPEM) Questionnaire, a patient-reported outcome measure assessing functional decline, recovery, crash-associated symptoms, and pacing adaptations in ME/CFS.", "url": "https://pubmed.ncbi.nlm.nih.gov/42998183/", "also": [ "me-cfs" ] }, { "pmid": "42997614", "title": "A New Outlook on Infection-Associated Chronic Conditions and Illnesses.", "journal": "Open forum infectious diseases", "pub_date": "2026-11-08", "authors": "Bertolli, Jeanne, Hinckley, Alison F, Mead, Paul S, Patel, Pragna et al.", "excerpt": "Infection-associated chronic conditions and illnesses (IACCI) encompass several debilitating syndromes with overlapping symptoms that have been identified and documented for decades, primarily following infectious disease outbreaks. Conditions following infection that are diagnosed with objective clinical tests have been relatively well characterized and accepted by the medical establishment, although the...", "url": "https://pubmed.ncbi.nlm.nih.gov/42997614/", "also": [ "me-cfs", "lyme" ] }, { "pmid": "42992899", "title": "Sex-Specific Plasma Proteomic Alterations Underpin Distinct COVID-19 Progression and Post-COVID-19 Condition.", "journal": "Journal of proteome research", "pub_date": "2026-11-06", "authors": "Lu, Qiuhan, Zhang, Yi, Yi, Shiyu, Wu, Yuwen et al.", "excerpt": "Sex differences in COVID-19 and its sequelae remain poorly understood, which hinders targeted therapies. We performed plasma proteomic analyses of 69 hospitalized patients with COVID-19 and 30 healthy controls from a prospective Chinese cohort.", "url": "https://pubmed.ncbi.nlm.nih.gov/42992899/", "also": [] }, { "pmid": "42992825", "title": "Incidence and risk factors of acute respiratory illness associated with influenza, COVID-19, and respiratory syncytial virus within a birth cohort study.", "journal": "Journal of virology", "pub_date": "2026-11-06", "authors": "Bird, Bryden, Thorn, Louise, Aminisani, Nayyereh, Wood, Tim et al.", "excerpt": "Influenza virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and respiratory syncytial virus (RSV) are leading causes of acute respiratory infections (ARIs). New Zealand's coronavirus disease 2019 (COVID-19) public health measures disrupted the circulation of these viruses in 2020-2021, creating a rare opportunity to explore the impact of potential immunity gaps on age-specific infection risk.", "url": "https://pubmed.ncbi.nlm.nih.gov/42992825/", "also": [] }, { "pmid": "42994070", "title": "Erratum to \"Persistent neuromuscular dysfunction in long COVID: A quantitative and single fiber EMG follow-up study\" [Neurophysiol Clin. 2026 Aug;56(4):103187].", "journal": "Neurophysiologie clinique = Clinical neurophysiology", "pub_date": "2026-11-06", "authors": "Khan, Benjamin Yamin Ali, Fanella, Gaia, Harbo, Thomas, Agergaard, Jane et al.", "excerpt": "No abstract available.", "url": "https://pubmed.ncbi.nlm.nih.gov/42994070/", "also": [] }, { "pmid": "42989040", "title": "Converging pathomechanisms link SARS-CoV-2 infection with major neurodegenerative diseases.", "journal": "Cellular and molecular neurobiology", "pub_date": "2026-11-06", "authors": "HeFeng, Feng Q, Martí-Sarrias, Andrea, Guvenilir, Heval Atas, de Sá, Renata Baptista Vieira et al.", "excerpt": "Neurological complications are among typical clinical manifestations, both during the acute phase of SARS-CoV-2 infection and long-term post-acute COVID-19 sequelae, i.e., Long COVID. A growing body of evidence connects SARS-CoV-2 infection to systemic inflammation, peripheral immune dysregulation, functional alteration of the blood-brain barrier (BBB), neuroinflammatory processes, mitochondrial dysfunction and...", "url": "https://pubmed.ncbi.nlm.nih.gov/42989040/", "also": [] }, { "pmid": "42991755", "title": "A novel model demonstrating that human immune cells promote multiorgan SARS-CoV-2 dissemination and human T cells limit anti-viral innate immunity.", "journal": "Frontiers in immunology", "pub_date": "2026-11-06", "authors": "Wolabaugh, Amber, Agashe, Vrushali V, Wang, Zicheng, Danzl, Nichole M et al.", "excerpt": "Despite extensive studies, many questions remain regarding the pathology and mechanisms behind Coronavirus disease 2019 (COVID-19), and particularly on post-acute sequelae of COVID-19 (PASC). Because existing mouse models cannot recapitulate human immune responses, we developed a human immune system (HIS) mouse model with physiologic expression of hACE2.", "url": "https://pubmed.ncbi.nlm.nih.gov/42991755/", "also": [] }, { "pmid": "42989775", "title": "\"I Picked Myself Up Through Prayer and Soups\": Factors Impeding and Enhancing Long COVID Recovery Among Latinos in South Texas.", "journal": "Journal of community psychology", "pub_date": "2026-11-06", "authors": "Alvarez-Hernandez, Luis R, Clark, Loren C, Uzoh, Hemma, Gonzales, Xavier F et al.", "excerpt": "We aimed to understand what factors have impeded and enhanced Long COVID recovery among Latinos in South Texas. Through community partners, 78 participants were part of seven focus groups.", "url": "https://pubmed.ncbi.nlm.nih.gov/42989775/", "also": [] }, { "pmid": "42987077", "title": "[Insights on biological markers in post-COVID condition: a scope review].", "journal": "Ciencia & saude coletiva", "pub_date": "2026-11-05", "authors": "Amorim, Amanda Dos Santos de, Porto, Evailson Ferreira, Oliveira, Márcio Vasconcelos", "excerpt": "Post-COVID condition (PCC) is characterized by the persistence of symptoms following acute SARS-CoV-2 infection. This scoping review aimed to identify and compile scientific evidence on biomarkers associated with PCC to elucidate its pathophysiology and support clinical diagnosis and management.", "url": "https://pubmed.ncbi.nlm.nih.gov/42987077/", "also": [] }, { "pmid": "42987066", "title": "[Death from post-COVID-19 conditions in Brazil: a descriptive study, 2020-2023].", "journal": "Ciencia & saude coletiva", "pub_date": "2026-11-05", "authors": "Couto, Rodrigo de Macedo, Boing, Alexandra Crispim", "excerpt": "Little is known about the magnitude of deaths and which comorbidities may contribute to the occurrence of outcomes among individuals with post-COVID conditions. This study aimed to identify deaths due to post-COVID conditions in Brazil from 2020 to 2023 and describe the consequential and contributing causes.", "url": "https://pubmed.ncbi.nlm.nih.gov/42987066/", "also": [] }, { "pmid": "42988415", "title": "Unravelling the mysteries of long COVID: what the microbiome can tell us.", "journal": "The European respiratory journal", "pub_date": "2026-11-05", "authors": "Leung, Janice M", "excerpt": "No abstract available.", "url": "https://pubmed.ncbi.nlm.nih.gov/42988415/", "also": [] }, { "pmid": "42987051", "title": "Tuberculous meningoencephalitis in a heart transplant recipient: a case report.", "journal": "Einstein (Sao Paulo, Brazil)", "pub_date": "2026-11-05", "authors": "Ferreira, Lucas Teixeira Fazio, Favato, Gileyre Rinaldi, Bittante, Carolina Devite, Bacal, Fernando et al.", "excerpt": "A 33-year-old woman who had undergone heart transplantation two years earlier for post-COVID-19 myocarditis was admitted with decompensated heart failure secondary to acute antibody-mediated rejection. During hospitalization, she developed sepsis, cytomegalovirus infection, acute kidney injury, and an incidental pulmonary miliary pattern on chest computed tomography, without microbiological confirmation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42987051/", "also": [] }, { "pmid": "42986753", "title": "Single-cell and spatial characterization of the human pancreas in cystic fibrosis.", "journal": "Cell reports", "pub_date": "2026-11-05", "authors": "Mummey, Hannah M, Corban, Sierra, Lucero, Jacinta, Melton, Rebecca L et al.", "excerpt": "Cystic fibrosis (CF) causes severely damaged pancreatic morphology and cystic fibrosis-related diabetes (CFRD), but the cellular drivers of CFRD in the pancreas are not understood. Here, we perform single-cell and spatial profiling of 2.04 M cells from 23 non-disease or CF pancreas donors.", "url": "https://pubmed.ncbi.nlm.nih.gov/42986753/", "also": [] }, { "pmid": "42987072", "title": "Risk factors for Post-COVID-19 Syndrome in patients hospitalized for severe acute respiratory syndrome: systematic review and meta-analysis.", "journal": "Ciencia & saude coletiva", "pub_date": "2026-11-05", "authors": "Soares, Sofia Ramos, Souza, Rafaela Santos Nogueira de, Barros, Loreena Uchôa Lira, Camboim et al.", "excerpt": "This study aims to identify the risk factors associated with the development of post-COVID-19 syndrome in patients discharged from hospitalizations due to severe acute respiratory syndrome. A systematic review of observational studies published between 2020 and 2023 was carried out in six databases.", "url": "https://pubmed.ncbi.nlm.nih.gov/42987072/", "also": [] }, { "pmid": "42985480", "title": "Rehabilitation professionals at the COVID-19 frontline: a testimony-informed narrative review of health-worker mortality, vaccine hesitancy, physiotherapy and telerehabilitation.", "journal": "Frontiers in rehabilitation sciences", "pub_date": "2026-11-05", "authors": "Npochinto Moumeni, Ibrahim", "excerpt": "COVID-19 placed an unprecedented burden on health workers and disrupted rehabilitation services. Existing reviews have examined health-worker infection and mortality, vaccine hesitancy and telerehabilitation separately; few have considered these dimensions together from the perspective of rehabilitation professionals.", "url": "https://pubmed.ncbi.nlm.nih.gov/42985480/", "also": [] }, { "pmid": "42986813", "title": "More common than we thought: Hypermobile Ehlers-Danlos Syndrome, comorbidity burden, and long COVID risk in a national cohort.", "journal": "PLOS digital health", "pub_date": "2026-11-05", "authors": "Pearson, Megan L, Laraway, Bryan J, Elias, Ellen R, Bilousova, Ganna et al.", "excerpt": "Hypermobile Ehlers-Danlos Syndrome (hEDS) is a complex, underdiagnosed connective tissue disorder characterized by widespread symptoms affecting multiple organ systems. Recent clinical observations suggest that individuals with hEDS may be at increased risk for persistent symptoms following COVID-19, commonly referred to as Long COVID.", "url": "https://pubmed.ncbi.nlm.nih.gov/42986813/", "also": [ "me-cfs", "pots", "mcas" ] }, { "pmid": "42988585", "title": "Metformin and Severe Post-COVID-19 Outcomes Among Individuals With Diabetes Mellitus.", "journal": "Diabetes, obesity & metabolism", "pub_date": "2026-11-05", "authors": "Dozier, Zachary B, Wang, Lin-Chiun, Ji, Yunwen, Anzalone, A Jerrod et al.", "excerpt": "We evaluated the relationship between metformin, one of the most commonly prescribed medications for individuals with diabetes, and COVID-19 sequelae. We evaluated a retrospective cohort of individuals in the National Clinical Cohort Collaborative with Type 2 diabetes mellitus and COVID-19 who were prescribed metformin or a dipeptidyl peptidase-4 inhibitor (DPP4i) at least 30 days before the onset of acute COVID-19...", "url": "https://pubmed.ncbi.nlm.nih.gov/42988585/", "also": [] }, { "pmid": "42985370", "title": "Management of Rhino-Orbital-Cerebral Mucormycosis Infection: Anesthetic Challenges.", "journal": "Current medical mycology", "pub_date": "2026-11-05", "authors": "Imantalab, Vali, Dodangeh Balakhani, Mohammad, Haghani, Iman, Rahmanian, Nazanin et al.", "excerpt": "Despite the application of surgery and antifungal therapy, rhino-orbital-cerebral mucormycosis is a severe and life-threatening fungal infection with high morbidity and mortality rates, particularly in immunocompromised patients. This review aimed to focus on the current evidence on perioperative anesthetic management of rhino-orbital-cerebral mucormycosis (ROCM), emphasizing the unique challenges posed by its...", "url": "https://pubmed.ncbi.nlm.nih.gov/42985370/", "also": [] }, { "pmid": "42985061", "title": "Effectiveness of an Extension for Community Health Outcomes case-based virtual community of practice model on clinician outcomes for the management of long COVID and fatiguing illnesses: a randomized control trial.", "journal": "Frontiers in health services", "pub_date": "2026-11-05", "authors": "Zuber, Alexandra, Rothwell, Jonathan T, Samaniego, Jane C, Sharp, Sydney P et al.", "excerpt": "Patients with Long COVID and other infection-associated chronic conditions (IACC) often face barriers to accessing specialist care, prompting the need to strengthen primary care capacity to manage these complex conditions. Our study evaluated the effectiveness of an ECHO case-based virtual community of practice model for improving clinician knowledge, confidence, and practice for Long COVID and other IACC in a...", "url": "https://pubmed.ncbi.nlm.nih.gov/42985061/", "also": [] } ], "me-cfs": [ { "pmid": "42996068", "title": "Fibromyalgia, Chronic Fatigue Syndrome, and Multiple Sclerosis are associated with lower translocator protein binding affinity genotypes.", "journal": "medRxiv : the preprint server for health sciences", "pub_date": "2026-11-08", "authors": "Jones, Chloe, Younger, Jarred", "excerpt": "Neuroinflammation is a known pathophysiologic mechanism in multiple sclerosis and a proposed mechanism in fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Positron Emission Tomography (PET) imaging of the translocator protein (TSPO) has been widely used to measure neuroinflammation, though second-generation ligands are highly sensitive to a single nucleotide polymorphism, rs6971...", "url": "https://pubmed.ncbi.nlm.nih.gov/42996068/", "also": [] } ], "pacvs": [], "lyme": [ { "pmid": "42995416", "title": "Cardiovascular Manifestations of Lyme Disease.", "journal": "Cardiology in review", "pub_date": "2026-11-08", "authors": "Manolis, Antonis A, Manolis, Theodora A, Vouliotis, Apostolos, Manolis, Antonis S", "excerpt": "Lyme disease is a tick-borne zoonosis caused by Borrelia burgdorferi that can involve multiple organ systems, including the cardiovascular (CV) system, noted in ~1-10% of untreated patients. This can produce atrioventricular (AV) or bundle branch block, atrial fibrillation, and myopericarditis in the acute phase, and dilated cardiomyopathy in the chronic phase.", "url": "https://pubmed.ncbi.nlm.nih.gov/42995416/", "also": [] } ], "gulf-war-illness": [], "pots": [], "mcas": [ { "pmid": "42992652", "title": "Mast Cell-Derived CCL2 Exacerbates Endometriosis Pain via Binding to CCR4.", "journal": "Omics : a journal of integrative biology", "pub_date": "2026-11-06", "authors": "Deng, Ya, Chen, Ping, Ding, Haigang", "excerpt": "Endometriosis (EMs) pain severely reduces patients' quality of life, but its underlying mechanisms are not fully understood. Mast cells and C-C motif chemokine ligand 2 (CCL2) are highly abundant in EMs lesions, yet their roles in neural sensitization remain unclear.", "url": "https://pubmed.ncbi.nlm.nih.gov/42992652/", "also": [] }, { "pmid": "42992522", "title": "Basophil and eosinophil dynamics as predictors of omalizumab resistance in chronic spontaneous urticaria.", "journal": "Cutaneous and ocular toxicology", "pub_date": "2026-11-06", "authors": "Oraloğlu, Göktürk, Süne, Ceren, Duman, Nilay, Demirel, Boratay Erin et al.", "excerpt": "Chronic spontaneous urticaria is a mast cell-driven skin disorder in which basophils and eosinophils contribute to inflammation. Omalizumab is effective for many patients, yet a subset remains resistant.", "url": "https://pubmed.ncbi.nlm.nih.gov/42992522/", "also": [] }, { "pmid": "42983188", "title": "Plant-derived Alkaloids for Allergic Rhinitis: Evidence, Exposure, Safety and Translational Readiness.", "journal": "Current pharmaceutical biotechnology", "pub_date": "2026-11-05", "authors": "Yang, Yaodong, Ma, Xuemei, Liu, Yuxin, Ma, Long et al.", "excerpt": "Allergic Rhinitis (AR) is an allergen-driven, IgE-mediated inflammatory disease of the nasal mucosa. Established therapies are effective for many patients, but incomplete symptom control, suboptimal adherence, and treatment preference sustain interest in new locally acting agents.", "url": "https://pubmed.ncbi.nlm.nih.gov/42983188/", "also": [] }, { "pmid": "42986481", "title": "Licoflavone B mitigates allergic rhinitis by restraining epithelial PI3K-AKT/NF-κB NLRP3 inflammasome signaling.", "journal": "Human cell", "pub_date": "2026-11-05", "authors": "Shen, Qi, Ma, Xiaoyao, Liu, Hui, Li, Xuemin et al.", "excerpt": "Allergic rhinitis remains highly prevalent and is often incompletely controlled by current therapies, while accumulating evidence implicates epithelial PI3K-AKT/NF-κB-mediated activation of the NLRP3 inflammasome in upper-airway inflammation. This study investigated whether the licorice-derived flavonoid Licoflavone B (LFB) alleviates allergic rhinitis by modulating this signaling axis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42986481/", "also": [] }, { "pmid": "42986406", "title": "Hesperidin alleviates allergic rhinitis by inhibiting NF-κB activation and restoring nasal epithelial barrier function.", "journal": "Medical molecular morphology", "pub_date": "2026-11-05", "authors": "Zhou, Kai, Wu, Qian, Han, Jiajia, Muratov, Muzaffar et al.", "excerpt": "This study evaluated the therapeutic effect of hesperidin (HES) on allergic rhinitis (AR) in a mouse model induced by ovalbumin (OVA). After inducing AR in BALB/c mice through OVA, the severity of allergic reactions was assessed through behavioral scoring.", "url": "https://pubmed.ncbi.nlm.nih.gov/42986406/", "also": [] } ], "other-post-viral": [] }, "trials": [ { "nct_id": "NCT07842302", "title": "Fighting Fatigue in Multiple Sclerosis: TMS vs. tDCS Efficacy.", "status": "ENROLLING_BY_INVITATION", "phase": "NA", "last_updated": "2026-11-10", "start_date": "2026-09-08", "sponsor": "Universitat Oberta de Catalunya", "sponsor_type": "OTHER", "agents": [ "Tms", "Tdcs" ], "conditions": [ "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT07842302" }, { "nct_id": "NCT07798570", "title": "Observational Study With CICR-NAM as a Food for Special Medicinal Purposes in Post-COVID Syndrome (PCS)", "status": "RECRUITING", "phase": "NA", "last_updated": "2026-11-10", "start_date": "2026-09-08", "sponsor": "University Hospital Schleswig-Holstein", "sponsor_type": "OTHER", "agents": [ "Cicr-Nam" ], "conditions": [ "long-covid" ], "mapped_conditions": [ "Long COVID / PASC" ], "link": "https://clinicaltrials.gov/study/NCT07798570" }, { "nct_id": "NCT07388550", "title": "Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I)", "status": "NOT_YET_RECRUITING", "phase": "PHASE1", "last_updated": "2026-11-10", "start_date": "2026-11-15", "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_type": "NIH", "agents": [ "Keytruda" ], "conditions": [ "long-covid" ], "mapped_conditions": [ "Long COVID / PASC" ], "link": "https://clinicaltrials.gov/study/NCT07388550" }, { "nct_id": "NCT07316127", "title": "Immunoadsorption in Autoimmune Long COVID", "status": "RECRUITING", "phase": "PHASE2", "last_updated": "2026-11-10", "start_date": "2026-01-01", "sponsor": "Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)", "sponsor_type": "OTHER", "agents": [ "Immunoadsorption" ], "conditions": [ "long-covid" ], "mapped_conditions": [ "Long COVID / PASC" ], "link": "https://clinicaltrials.gov/study/NCT07316127" }, { "nct_id": "NCT05350774", "title": "Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2", "status": "ENROLLING_BY_INVITATION", "phase": "PHASE2", "last_updated": "2026-11-10", "start_date": "2023-07-10", "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_type": "NIH", "agents": [ "Iv Normal Saline", "Iv Immunoglobulin" ], "conditions": [ "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT05350774" }, { "nct_id": "NCT02725060", "title": "Autoimmune Basis for Postural Tachycardia Syndrome", "status": "ACTIVE_NOT_RECRUITING", "phase": "NA", "last_updated": "2026-11-10", "start_date": "2016-02", "sponsor": "Vanderbilt University Medical Center", "sponsor_type": "OTHER", "agents": [ "Phenylephrine", "Isoproterenol", "25 Micro-Ci Of Radiation", "24-Hour Heart Rhythm And Blood Pressure Monitoring", "Quantitative Axonal Sudomotor Reflex Testing", "Autonomic Function Tests", "Rebreathing Test", "Assessment Of Splanchnic Capacitance", "Microneurography" ], "conditions": [ "pots", "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT02725060" }, { "nct_id": "NCT07925944", "title": "Subgrouping Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Linking the Powerhouses of Cells to the Autonomic Nervous System", "status": "ACTIVE_NOT_RECRUITING", "phase": "NA", "last_updated": "2026-11-09", "start_date": "2024-10-21", "sponsor": "Vrije Universiteit Brussel", "sponsor_type": "OTHER", "agents": [ "Exercise Test", "Active Standing Test" ], "conditions": [ "me-cfs" ], "mapped_conditions": [ "ME/CFS" ], "link": "https://clinicaltrials.gov/study/NCT07925944" }, { "nct_id": "NCT07526558", "title": "Mast Cell Treatment in Post-tick Bite Illness (PTBI)", "status": "NOT_YET_RECRUITING", "phase": "PHASE2", "last_updated": "2026-11-09", "start_date": "2027-01", "sponsor": "University of North Carolina, Chapel Hill", "sponsor_type": "OTHER", "agents": [ "Ketotifen", "Fexofenadine", "Cromolyn Sodium" ], "conditions": [ "mcas", "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT07526558" }, { "nct_id": "NCT07197905", "title": "Restoring Iron Deficiency in POTS", "status": "ACTIVE_NOT_RECRUITING", "phase": "PHASE2", "last_updated": "2026-11-09", "start_date": "2025-11-24", "sponsor": "Vanderbilt University Medical Center", "sponsor_type": "OTHER", "agents": [ "Intravenous Iron" ], "conditions": [ "pots", "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT07197905" }, { "nct_id": "NCT07478172", "title": "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease", "status": "ACTIVE_NOT_RECRUITING", "phase": "NA", "last_updated": "2026-11-06", "start_date": "2026-03-10", "sponsor": "University of Missouri-Columbia", "sponsor_type": "OTHER", "agents": [ "Whole-Body Electrical Muscle Stimulation Exercise" ], "conditions": [ "pots", "other-post-viral" ], "mapped_conditions": [ "Unspecified / Overlap" ], "link": "https://clinicaltrials.gov/study/NCT07478172" }, { "nct_id": "NCT07874217", "title": "Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study", "status": "RECRUITING", "phase": "NA", "last_updated": "2026-11-05", "start_date": "2026-10-05", "sponsor": "Oxford Brookes University", "sponsor_type": "OTHER", "agents": [ "Cryotherapy" ], "conditions": [ "long-covid", "me-cfs" ], "mapped_conditions": [ "Long COVID / PASC", "ME/CFS" ], "link": "https://clinicaltrials.gov/study/NCT07874217" }, { "nct_id": "NCT06404047", "title": "RECOVER-ENERGIZE Platform Protocol", "status": "COMPLETED", "phase": "NA", "last_updated": 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