{
  "id": "2026-W25",
  "year": 2026,
  "week": 25,
  "week_monday": "2026-06-15",
  "week_sunday": "2026-06-21",
  "asof": "2026-06-21",
  "window_start": "2026-06-15",
  "window_end": "2026-06-21",
  "window_days": 7,
  "widened": false,
  "strict_study_count": 33,
  "strict_trial_count": 5,
  "study_count": 33,
  "trial_count": 5,
  "studies": {
    "long-covid": [],
    "me-cfs": [
      {
        "pmid": "42322758",
        "title": "Study on Sijunzi decoction regulating intestinal microbiota structure and metabolic profile for improving chronic fatigue syndrome.",
        "journal": "Journal of chromatography. B, Analytical technologies in the biomedical and life sciences",
        "pub_date": "2026-06-21",
        "authors": "Shan, Yi, Jin, Jin, Wu, Yiduo, Yu, Runsheng et al.",
        "excerpt": "Chronic fatigue syndrome (CFS) is a syndrome encompassing several systemic diseases. Sijunzi Decoction (SJZD) is a classic formula in traditional Chinese medicine (TCM) for the treatment of spleen deficiency syndrome.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42322758/",
        "also": []
      },
      {
        "pmid": "42320559",
        "title": "Systems neuroendocrinology in ME/CFS and long COVID: a chronobiological framework for hormone-based research.",
        "journal": "Frontiers in neuroendocrinology",
        "pub_date": "2026-06-20",
        "authors": "Thomas, Natalie, Huang, Katherine, Schneider-Futschik, Elena K, Pollack, Beth et al.",
        "excerpt": "Hormonal dysregulation is increasingly reported in ME/CFS and Long COVID, yet the broader role of neuroendocrine disruption in these conditions remains underexplored. While changes in steroid, peptide, and neuropeptide hormones have been identified, these findings are often considered in isolation and without attention to their timing or integration within broader physiological systems.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42320559/",
        "also": []
      },
      {
        "pmid": "42321833",
        "title": "Gastrointestinal symptoms correlate with core clinical features and systemic inflammation in myalgic encephalomyelitis/chronic fatigue syndrome.",
        "journal": "Journal of translational medicine",
        "pub_date": "2026-06-20",
        "authors": "Brown, Mikayla, Vernon, Suzanne D, Indart, Alyssa C, Green, Peter H et al.",
        "excerpt": "Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem illness marked by fatigue, cognitive impairment, and post-exertional malaise. Gastrointestinal (GI) symptoms are frequently reported, yet their relationship to central features of the illness and biological correlates remains poorly understood.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42321833/",
        "also": []
      },
      {
        "pmid": "42313182",
        "title": "[Not Available].",
        "journal": "Der Nervenarzt",
        "pub_date": "2026-06-18",
        "authors": "Erbguth, F, Tegenthoff, M, Böwering-Möllenkamp, C, Schain, H et al.",
        "excerpt": "No abstract available.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42313182/",
        "also": []
      },
      {
        "pmid": "42310705",
        "title": "Effectiveness of adapted physical activity and therapeutic exercise programme in improving chronic fatigue syndrome in long COVID, delivered via hospital-based rehabilitation versus telerehabilitation.",
        "journal": "Trials",
        "pub_date": "2026-06-18",
        "authors": "Kabir, Feroz, Yin, Khin Nyein, Jeffree, Mohammad Saffree, Ahmedy, Fatimah Binti et al.",
        "excerpt": "Long COVID is a prevalent condition characterised by pain, fatigue, disability, and a multitude of health issues. There are various treatment options for managing long COVID symptoms, including non-pharmacological interventions like physiotherapy and rehabilitation, which can be effectively delivered either in institutional care settings or via telerehabilitation.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42310705/",
        "also": []
      },
      {
        "pmid": "42298601",
        "title": "Self-management support needs for individuals with Myalgic Encephalomyelitis and their next of kin - a qualitative study.",
        "journal": "BMC health services research",
        "pub_date": "2026-06-16",
        "authors": "Grønning, Kjersti, Lysfjord, Liv Eli, Røstad, Ann Katrin Hagen",
        "excerpt": "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, disabling condition with limited evidence-based treatment options. Self-management support is recommended to improve people's coping and quality of life, yet little is known about whether the provided self-management support meet individuals with ME/CFS and their next of kins needs.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42298601/",
        "also": []
      },
      {
        "pmid": "42289444",
        "title": "Fatigue-associated gut bacteria in Japanese healthy adults characterized by metagenomic analysis.",
        "journal": "Scientific reports",
        "pub_date": "2026-06-15",
        "authors": "Masuoka, Hiroaki, Miyatake, Takumi, Park, Jonguk, Negishi, Hiroki et al.",
        "excerpt": "Emerging evidence suggests that fatigue caused by accumulated stress may serve as a prodromal symptom of psychiatric disorders, and gut microbiome dysbiosis has been reported in many such conditions. However, little is known about microbial and metabolic signatures associated with fatigue in otherwise healthy individuals.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42289444/",
        "also": []
      },
      {
        "pmid": "42291861",
        "title": "Approach to Fatigue in Primary Care: A Practical Diagnostic Framework for General Practitioners.",
        "journal": "Cureus",
        "pub_date": "2026-06-15",
        "authors": "Elbaroumi, Omar",
        "excerpt": "Fatigue is one of the most common presenting complaints in primary care and poses a significant diagnostic challenge due to its multifactorial aetiology. While the majority of cases are benign and self-limiting, fatigue may also represent an early manifestation of serious underlying pathology.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42291861/",
        "also": []
      }
    ],
    "pacvs": [],
    "lyme": [],
    "gulf-war-illness": [
      {
        "pmid": "42296096",
        "title": "Association between deployment and Gulf War Illness and adverse COVID outcomes in a nationwide cohort of 1990-1991 Gulf Era war veterans in the VA's Million Veteran Program.",
        "journal": "PloS one",
        "pub_date": "2026-06-15",
        "authors": "White, Donna L, NonoDjotsa, Alice B S, Ahmed, Sarah T, Boyle, Stephen H et al.",
        "excerpt": "U.S. military veterans deployed to the Persian Gulf to serve in the 1990-1991 Gulf War (GWVs) have expressed concerns about potential increased risk of experiencing adverse COVID-related health outcomes given broad near-unique exposure to multiple diverse toxic agents during deployment and ongoing ~30% prevalence of Gulf War Illness (GWI+), a chronic, medically unexplained multi-symptom disorder associated with...",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42296096/",
        "also": []
      }
    ],
    "pots": [
      {
        "pmid": "42305393",
        "title": "Robotic management of superior mesenteric artery syndrome after weight loss: a case report.",
        "journal": "Journal of surgical case reports",
        "pub_date": "2026-06-17",
        "authors": "Kontogiannis, Cristina, Asif, Sami, Kharod, Amit",
        "excerpt": "Superior mesenteric artery (SMA) syndrome is a rare cause of proximal intestinal obstruction resulting from compression of the third portion of the duodenum between the aorta and the SMA. It most commonly occurs in slender individuals or those experiencing rapid weight loss, but presentations can be atypical and diagnostically challenging.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42305393/",
        "also": []
      },
      {
        "pmid": "42308205",
        "title": "Adverse events following HPV vaccine reported to the Vaccine Adverse Event Reporting System.",
        "journal": "PloS one",
        "pub_date": "2026-06-17",
        "authors": "Zhang, Siqi, Li, Yu, Liu, Miaomiao, Yang, Jiajia et al.",
        "excerpt": "Vaccination against high-risk HPV types is a key preventive measure. However, concerns regarding vaccine safety may hinder vaccination efforts.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42308205/",
        "also": []
      },
      {
        "pmid": "42299385",
        "title": "Unusual presentation of scleroderma: case report.",
        "journal": "AME case reports",
        "pub_date": "2026-06-16",
        "authors": "Finsterer, Josef",
        "excerpt": "The combination of neurological, cardiac, and pulmonary disease in patients with systemic sclerosis (SS) is rare. The aim of the study was to report a patient with SS who manifested with migraine without aura, Raynaud's phenomenon, pulmonary hypertension, and postural tachycardia syndrome (POTS), a combination which has not been previously reported.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299385/",
        "also": []
      },
      {
        "pmid": "42298945",
        "title": "Hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome: patient experiences, disability and implications for rehabilitation.",
        "journal": "International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation",
        "pub_date": "2026-06-16",
        "authors": "Brandt, Lindsay, Kondratek, Melodie, Kim, Limmy, Ohanian, Hailey et al.",
        "excerpt": "The diagnosis and management of hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome (HSD/hEDS) are a healthcare challenge because of the wide array of symptoms, lack of diagnostic biomarkers, and evolving management guidelines. This study aimed to describe patient experiences, disability, and self-perceived success managing HSD/hEDS, with or without comorbid postural orthostatic tachycardia...",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42298945/",
        "also": [
          "mcas"
        ]
      },
      {
        "pmid": "42299763",
        "title": "How does postural orthostatic tachycardia syndrome (POTS) affect pediatric patients?",
        "journal": "Nursing",
        "pub_date": "2026-06-16",
        "authors": "Gerik, Daniella J, Cadet, Myriam J",
        "excerpt": "Postural orthostatic tachycardia syndrome (POTS) is a disorder characterized by a sudden onset of orthostatic intolerance upon standing, which may be relieved when lying down. The most common complications associated with POTS are trauma or injury from falling or fainting.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299763/",
        "also": []
      },
      {
        "pmid": "42299168",
        "title": "Dysautonomia and Postural Orthostatic Tachycardia Syndrome (POTS) in the ENT Clinic: Differentiating Orthostatic Dizziness From Vestibular Migraine and Persistent Postural-Perceptual Dizziness (PPPD).",
        "journal": "Cureus",
        "pub_date": "2026-06-16",
        "authors": "Zitser, Philip, Kolomiyets, Ilana, Imran, Maheen, Kulkarni, Aashi et al.",
        "excerpt": "One of the most common complaints in ENT clinics is dizziness. Although most cases are caused by vestibular neuritis and benign paroxysmal positional vertigo (BPPV), a significant number of patients experience non-vestibular dizziness.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299168/",
        "also": []
      }
    ],
    "mcas": [
      {
        "pmid": "42319568",
        "title": "Next-generation heparin antidotes: \"Exosomes as a biocompatible alternative to protamine sulfate\".",
        "journal": "Molecular biology reports",
        "pub_date": "2026-06-19",
        "authors": "Bahar, Leyla, Tüysüz, Mehmet Erin, Omay, Pınar Hüner, Kınay, Vehbi et al.",
        "excerpt": "Controlling bleeding is one of the most fundamental challenges in cardiac surgery. Bleeding is controlled by neutralising heparin with protamine.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42319568/",
        "also": []
      },
      {
        "pmid": "42316564",
        "title": "Mast Cells and Cardiovascular Disorders.",
        "journal": "Current vascular pharmacology",
        "pub_date": "2026-06-19",
        "authors": "Manolis, Antonis A, Manolis, Theodora A, Vouliotis, Apostolos, Manolis, Antonis S",
        "excerpt": "Mastocytosis is a neoplasm characterised by clonal proliferation of mast cells (MCs) in the skin and other organs, including the heart, and symptoms produced by MC-derived mediators. MC activation syndrome (MCAS) relates to increased and inappropriate activation of MCs without clonal proliferation.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42316564/",
        "also": []
      },
      {
        "pmid": "42314808",
        "title": "Ethnopharmacological investigation of Elaeocarpus sylvestris leaf extract in mitigating atopic dermatitis-like lesions via inflammatory signaling modulation.",
        "journal": "Journal of ethnopharmacology",
        "pub_date": "2026-06-19",
        "authors": "Kim, So-Yeon, Do, Young-Ju, Lee, Su-Jung, Cho, Ye Eun et al.",
        "excerpt": "Historically, Elaeocarpus sylvestris has served as a traditional medicinal agent for inflammatory disorders across East Asia. Recent studies have reported its antioxidant and anti-inflammatory activities, supporting its potential as a natural therapeutic resource for inflammatory skin diseases such as atopic dermatitis (AD).",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42314808/",
        "also": []
      },
      {
        "pmid": "42316559",
        "title": "Epithelial Duox2 Drives Chronic Colitis-Associated Fibrosis via the NLRP3-IL-33-Mast Cell Axis.",
        "journal": "Combinatorial chemistry & high throughput screening",
        "pub_date": "2026-06-19",
        "authors": "Chen, Zhixiong, Yang, Juanmin, He, Zhigang",
        "excerpt": "Intestinal fibrosis is a common and serious complication of chronic inflammatory bowel disease (IBD) associated with stricture and obstruction. Although oxidative stress has been associated with IBD, how Duox2, the major source of ROS in gut epithelium, promotes fibrosis remains unknown.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42316559/",
        "also": []
      },
      {
        "pmid": "42314830",
        "title": "Critical evaluation of the key mediators causing life-threatening symptoms during human anaphylaxis.",
        "journal": "Drug discovery today",
        "pub_date": "2026-06-19",
        "authors": "Boehm, Thomas, Jilma, Bernd",
        "excerpt": "Most pathophysiologically oriented anaphylaxis reviews list a plethora of mediators purportedly involved in symptom development during severe anaphylaxis. However, how many mediators are responsible for life-threatening anaphylaxis symptoms?",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42314830/",
        "also": []
      },
      {
        "pmid": "42315046",
        "title": "Association of the endosomal TLR4 pathway with dorsolateral prostatic remodeling induced by perinatal phthalate mixture exposure in rats.",
        "journal": "Reproductive toxicology (Elmsford, N.Y.)",
        "pub_date": "2026-06-19",
        "authors": "Maria, Vinícius Luís Rocha da Silva, Santana, Ana Clara Pacheco de, Souza, Patrick Vieira, Rocha et al.",
        "excerpt": "Phthalates are endocrine disruptors that alter the homeostasis of hormone-dependent organs. Perinatal exposure to endocrine disruptors can program different organs and promote morphological and metabolic alterations, increasing susceptibility to diseases later in life, as proposed by the Developmental Origins of Health and Disease (DOHaD) hypothesis.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42315046/",
        "also": []
      },
      {
        "pmid": "42314929",
        "title": "Acalabrutinib for long-term prevention of recurrent idiopathic anaphylaxis.",
        "journal": "The journal of allergy and clinical immunology. In practice",
        "pub_date": "2026-06-19",
        "authors": "Tucker, James R, Wanandy, Troy, Lau, Wun Yee, Mulcahy, Emily M et al.",
        "excerpt": "No abstract available.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42314929/",
        "also": []
      },
      {
        "pmid": "42315097",
        "title": "Abluminal plasma induces vasoconstriction meditated by serotonin and counterbalanced by endothelial nitric oxide synthase in healthy and malarial mouse arteries.",
        "journal": "American journal of physiology. Heart and circulatory physiology",
        "pub_date": "2026-06-19",
        "authors": "Sanches, Guilherme S, Hakim, Md Abdul, Brooks, Steven D, Marins, Thais da Silva Barenco et al.",
        "excerpt": "No abstract available.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42315097/",
        "also": []
      },
      {
        "pmid": "42310859",
        "title": "Systemic Mastocytosis in Adults: 2026 Update on Diagnosis, Risk Stratification and Management.",
        "journal": "American journal of hematology",
        "pub_date": "2026-06-18",
        "authors": "Pardanani, Animesh",
        "excerpt": "Systemic mastocytosis (SM) results from clonal proliferation of mast cells (MC) in extra-cutaneous organs. The major criterion is the presence of multifocal MC clusters in the bone marrow and/or extracutaneous organs.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42310859/",
        "also": []
      },
      {
        "pmid": "42313027",
        "title": "Kounis Syndrome Triggered by Hymenoptera Stings and Exacerbated by Streptokinase.",
        "journal": "JACC. Case reports",
        "pub_date": "2026-06-18",
        "authors": "Chai, Siew Yap, Liew, Kai Soon, Soh, Kok Ming, Subramanian, Seetha Devi et al.",
        "excerpt": "Kounis syndrome (KS) is an allergy-mediated acute coronary syndrome that is frequently under-recognized and potentially life threatening. A 52-year-old man developed an inferior ST-segment elevation myocardial infarction following a bee swarm attack.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42313027/",
        "also": []
      },
      {
        "pmid": "42311633",
        "title": "Any role for respiratory allergens in IBS symptoms? From pathogenetic hypothesis to therapeutic implications.",
        "journal": "Frontiers in allergy",
        "pub_date": "2026-06-18",
        "authors": "Rossi, Carlo Maria, Lenti, Marco Vincenzo, Di Sabatino, Antonio",
        "excerpt": "Irritable bowel syndrome is a common disorder associated with substantial impairment in quality of life and remains challenging to manage due to its heterogeneous and incompletely understood pathophysiology leading to high rates of treatment failure. Recent evidence supports the existence of distinct IBS endotypes, including an emerging atopic variant characterised by allergic comorbidities, type 2 inflammation, and...",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42311633/",
        "also": []
      },
      {
        "pmid": "42299106",
        "title": "Rolling Up Transition Metal Chalcogenides/Oxide Heterostructures Enables Polarity-Tunable and High-Switchable Memristors.",
        "journal": "Advanced materials (Deerfield Beach, Fla.)",
        "pub_date": "2026-06-16",
        "authors": "Wang, Xiaofan, Chen, Xiaokai, Qiao, Ruixi, Xu, Jing et al.",
        "excerpt": "Harnessing transition metal dichalcogenides (TMDCs) for memristors provides a promising pathway toward high-density data storage and neuromorphic functionalities. Yet the single operation mode and insufficient on/off ratio extremely restrict the ultimate device performance.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299106/",
        "also": []
      },
      {
        "pmid": "42299718",
        "title": "Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria.",
        "journal": "Journal of the European Academy of Dermatology and Venereology : JEADV",
        "pub_date": "2026-06-16",
        "authors": "Bizjak-Suran, Mojca, Fležar, Matjaž, Pereira, Manuel Pedro",
        "excerpt": "Chronic inducible urticarias (CIndUs), including symptomatic dermographism (SD), cholinergic urticaria (CholU) and cold urticaria (ColdU), are mast cell (MC)-driven conditions triggered by subtype-specific, definite and reproducible stimuli. Although often considered self-limiting, these diseases can persist for years and significantly impair quality of life.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299718/",
        "also": []
      },
      {
        "pmid": "42299450",
        "title": "Anaphylaxis during hemodialysis associated with a polysulfone membrane: evidence from basophil activation testing.",
        "journal": "Kidney research and clinical practice",
        "pub_date": "2026-06-16",
        "authors": "Jung, Ji Yong, Moon, Da-Hye, Kim, Hyunsook, Chang, Jae Hyun et al.",
        "excerpt": "Dialyzer-associated anaphylaxis is an uncommon but serious complication of hemodialysis. Although severe anaphylaxis is rare, milder hypersensitivity reactions are likely underrecognized and frequently misattributed to cardiopulmonary or volume-related causes.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42299450/",
        "also": []
      },
      {
        "pmid": "42292825",
        "title": "Integrative machine learning and network toxicology framework for assessing environmental pollutant TCDD-induced osteoarthritis risk: a computational cheminformatics approach.",
        "journal": "Frontiers in pharmacology",
        "pub_date": "2026-06-15",
        "authors": "Li, Lei, Zhang, Yihong, Qiu, Wenkui, Li, Xiaolong et al.",
        "excerpt": "Osteoarthritis (OA) is a prevalent degenerative joint disease influenced by both genetic susceptibility and environmental factors. Increasing evidence suggests that exposure to persistent environmental pollutants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), may contribute to OA progression; however, the molecular mechanisms underlying these effects remain unclear.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42292825/",
        "also": []
      },
      {
        "pmid": "42295153",
        "title": "Characterization of a mouse model to study mechanisms of hemophilia A pain.",
        "journal": "Blood advances",
        "pub_date": "2026-06-15",
        "authors": "Fouda, Raghda T, Argueta, Donovan Alexander, Goel, Yugal, Velasco, Graham J et al.",
        "excerpt": "Pain is a debilitating feature of hemophilia A (HA), yet it remains understudied. We developed models of chronic and acute pain in factor VIII knock-out (FVIIIKO; B6;129S-FVIIItm1Kaz/J), demonstrating characteristic features of hemarthrosis pain and gait.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42295153/",
        "also": []
      }
    ],
    "other-post-viral": [
      {
        "pmid": "42305968",
        "title": "Efficacy and safety of Shufeng Huashi formula for post-infectious cough: study protocol for a randomized control trial.",
        "journal": "Frontiers in medicine",
        "pub_date": "2026-06-17",
        "authors": "Zhang, Xinyi, Li, Yirun, Han, Yuxin, Zhang, Hongchun",
        "excerpt": "Post-infectious cough (PIC) refers to a type of persistent cough triggered by respiratory tract infections that remains unresolved after the initial infection is controlled. It significantly impacts daily life, work, and overall quality of life.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42305968/",
        "also": []
      },
      {
        "pmid": "42289385",
        "title": "Photodistributed RIME Syndrome Treated With Etanercept.",
        "journal": "Pediatric dermatology",
        "pub_date": "2026-06-15",
        "authors": "Javaheri, Elika D, Harb, Dana, Damon, Amanda, Borch-Christensen, Bo et al.",
        "excerpt": "Reactive infectious mucocutaneous eruption (RIME) is a post-infectious mucositis which primarily affects pediatric patients. We report a 14-year-old girl with recent intensive sun exposure who developed RIME in a photodistributed pattern.",
        "url": "https://pubmed.ncbi.nlm.nih.gov/42289385/",
        "also": []
      }
    ]
  },
  "trials": [
    {
      "nct_id": "NCT06974084",
      "title": "A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID",
      "status": "NOT_YET_RECRUITING",
      "phase": "PHASE2",
      "last_updated": "2026-06-18",
      "start_date": "2026-07-15",
      "sponsor": "HealthBio, Inc.",
      "sponsor_type": "INDUSTRY",
      "agents": [
        "Maraviroc",
        "Atorvastatin, 10Mg, 20Mg, 40Mg"
      ],
      "conditions": [
        "long-covid"
      ],
      "mapped_conditions": [
        "Long COVID / PASC"
      ],
      "link": "https://clinicaltrials.gov/study/NCT06974084"
    },
    {
      "nct_id": "NCT06142253",
      "title": "Water-based Activity to Enhance Recovery in Long COVID-19",
      "status": "RECRUITING",
      "phase": "NA",
      "last_updated": "2026-06-18",
      "start_date": "2024-12-01",
      "sponsor": "VA Office of Research and Development",
      "sponsor_type": "FED",
      "agents": [
        "Water+Ct"
      ],
      "conditions": [
        "long-covid"
      ],
      "mapped_conditions": [
        "Long COVID / PASC"
      ],
      "link": "https://clinicaltrials.gov/study/NCT06142253"
    },
    {
      "nct_id": "NCT06593600",
      "title": "Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)",
      "status": "ACTIVE_NOT_RECRUITING",
      "phase": "PHASE2",
      "last_updated": "2026-06-17",
      "start_date": "2024-11-13",
      "sponsor": "Regeneron Pharmaceuticals",
      "sponsor_type": "INDUSTRY",
      "agents": [
        "Regn7544"
      ],
      "conditions": [
        "pots",
        "other-post-viral"
      ],
      "mapped_conditions": [
        "Unspecified / Overlap"
      ],
      "link": "https://clinicaltrials.gov/study/NCT06593600"
    },
    {
      "nct_id": "NCT05967052",
      "title": "Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or Complex Rehabilitation",
      "status": "TERMINATED",
      "phase": "PHASE2",
      "last_updated": "2026-06-17",
      "start_date": "2023-10-24",
      "sponsor": "National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland",
      "sponsor_type": "NETWORK",
      "agents": [
        "Pregabalin",
        "Independent Walking Training",
        "Gradual Movement Therapy In The Ward",
        "Telerehabilitation",
        "Psychotherapy"
      ],
      "conditions": [
        "me-cfs"
      ],
      "mapped_conditions": [
        "ME/CFS"
      ],
      "link": "https://clinicaltrials.gov/study/NCT05967052"
    },
    {
      "nct_id": "NCT07651371",
      "title": "Effects of a Physical Rehabilitation Program on Long COVID",
      "status": "COMPLETED",
      "phase": "NA",
      "last_updated": "2026-06-16",
      "start_date": "2021-01-05",
      "sponsor": "Universidade do Estado do Pará",
      "sponsor_type": "OTHER",
      "agents": [
        "Physical Rehabilitation",
        "Treadmill Ergometer",
        "Pulley"
      ],
      "conditions": [
        "long-covid"
      ],
      "mapped_conditions": [
        "Long COVID / PASC"
      ],
      "link": "https://clinicaltrials.gov/study/NCT07651371"
    }
  ],
  "feed_latest_pub_date": "2026-07-10",
  "numbers": {
    "studies_tracked": 544,
    "trials_tracked": 620,
    "biomarkers_catalogued": 546,
    "feeds": 8
  },
  "feed_updates": {
    "long-covid": "2026-07-07",
    "me-cfs": "2026-07-06",
    "pacvs": "2026-06-25",
    "lyme": "2026-07-08",
    "gulf-war-illness": "2026-07-09",
    "pots": "2026-07-10",
    "mcas": "2026-07-10",
    "other-post-viral": "2026-06-25"
  },
  "trials_last_run": "2026-06-26",
  "generated_at": "2026-10-07T22:29:14+00:00"
}
