{
  "schema_version": "2.0.0",
  "id": "marimoutou-2012-gendarmes",
  "name": "Réunion chikungunya gendarmes comparative cohort (Marimoutou)",
  "aliases": [
    "French military policemen chikungunya cohort"
  ],
  "outbreak_event": "Réunion chikungunya outbreak 2005-06",
  "pathogen_id": "chikungunya-virus",
  "pathogen_class": "virus",
  "exposure_ascertainment": "serology",
  "design": "retrospective_cohort",
  "denominator_defined": "yes",
  "denominator_method": "Occupational cohort of French gendarmes deployed on Réunion during the 2006 outbreak, classified by CHIKV serostatus; uninfected (CHIK-) gendarmes of the same force serve as an occupationally comparable unexposed group.",
  "recruitment_source": "occupational",
  "time_zero_definition": "Acute chikungunya infection during the 2006 Réunion outbreak",
  "time_zero_precision": "quarter",
  "control_group": "unexposed_unmatched",
  "control_matching_variables": [
    "occupation",
    "deployment setting"
  ],
  "n_source_population": null,
  "n_enrolled": 382,
  "n_analysed": 382,
  "followups": [
    {
      "months": 30,
      "n_assessed": 382,
      "n_lost": null
    }
  ],
  "max_followup_months": 30,
  "instruments": [
    "sf-36",
    "somatic-symptom-self-report"
  ],
  "case_definition": "author_defined",
  "pem_assessed": "no",
  "objective_measures": [
    "none"
  ],
  "specimens_collected": true,
  "specimen_types": [
    "serum"
  ],
  "acute_phase_specimens": "no",
  "storage": null,
  "biobank_status": "unknown",
  "consent_future_use": "unknown",
  "external_access": "unknown",
  "contact": null,
  "registration_id": null,
  "funders": [
    "French Military Health Service"
  ],
  "conflicts": null,
  "data_availability": null,
  "notes": "Comparative cohort of 85 CHIKV-infected vs 297 uninfected gendarmes assessed 30 months after the outbreak, with occupationally comparable unexposed controls and lower quality of life plus higher rheumatic, headache and fatigue morbidity in the infected. One of the strongest comparative symptom datasets in the chikungunya literature; per-symptom prevalence percentages are reported in the paper's tables (behind a subscription) and have not yet been extracted, so symptom_findings are intentionally empty pending full-text verification.",
  "symptom_inventory_scope": "targeted_panel",
  "n_symptoms_queried": null,
  "symptom_instrument_note": "Rheumatic, general and quality-of-life symptoms compared between CHIK+ and CHIK-; numeric per-symptom prevalences await full-text extraction.",
  "related_cohorts": [
    {
      "id": "telechik-reunion",
      "relation": "sibling_analysis"
    },
    {
      "id": "schilte-2013-chikungunya-reunion",
      "relation": "sibling_analysis"
    }
  ],
  "last_verified": "2026-07-20",
  "verified_by": "OSMF research-tracker (web-verified against source)",
  "publications": [
    {
      "id": "marimoutou-2012",
      "title": "Morbidity and impaired quality of life 30 months after chikungunya infection: comparative cohort of infected and uninfected French military policemen in Reunion Island",
      "authors": "Marimoutou C, Vivier E, Oliver M, Boutin JP, Simon F.",
      "year": 2012,
      "journal": "Medicine (Baltimore)",
      "doi": "10.1097/MD.0b013e318260b604",
      "pmid": "22732952",
      "url": "https://pubmed.ncbi.nlm.nih.gov/22732952/",
      "open_access": false,
      "is_primary_cohort_paper": true
    }
  ],
  "harmonisation_ruleset": "pais-harmony-v1",
  "observations": []
}