{
  "slug": "hepatitis-c",
  "id": "hepatitis-c-biomarkers",
  "condition": {
    "name": "Hepatitis C",
    "shortName": "Hepatitis C",
    "alternateNames": []
  },
  "page": {
    "title": "Hepatitis C Biomarker Atlas | Blood Tests & Molecular Alterations",
    "breadcrumbName": "Hepatitis C Biomarkers",
    "description": "Searchable atlas of Hepatitis C biomarkers, from peer-reviewed literature comparing patient levels vs. healthy controls.",
    "keywords": [
      "Hepatitis C biomarkers",
      "Hepatitis C blood tests",
      "biomarker atlas",
      "biomarker database"
    ],
    "canonical": "https://research.opensourcemed.info/hepatitis-c-biomarkers.html",
    "hero": "Molecular alterations reported in Hepatitis C compared to healthy controls, from peer-reviewed literature.",
    "dateModified": "2026-07-03"
  },
  "categories": {
    "hepatic": "Hepatic"
  },
  "filters": [
    "hepatic"
  ],
  "markers": [
    {
      "name": "ALT",
      "alternateName": "ALT",
      "direction": "up",
      "category": "hepatic",
      "comparison": "acute/chronic HCV infection vs healthy reference range",
      "symptoms": "",
      "reference": {
        "citation": "Woo et al. 2024",
        "doi": "10.3390/pathogens13040331"
      }
    },
    {
      "name": "AST",
      "alternateName": "AST",
      "direction": "up",
      "category": "hepatic",
      "comparison": "chronic HCV (CHC) patients vs healthy controls",
      "symptoms": "",
      "reference": {
        "citation": "Al-Rawaf et al. 2024",
        "doi": "10.1186/s12860-024-00514-8"
      }
    },
    {
      "name": "FIB-4 Index",
      "alternateName": "FIB-4",
      "direction": "up",
      "category": "hepatic",
      "comparison": "chronic HCV patients with advanced liver fibrosis vs early-stage disease (FIB-4 <1.45)",
      "symptoms": "",
      "reference": {
        "citation": "Krassenburg et al. 2023",
        "doi": "10.1136/bmjgast-2023-001209"
      }
    },
    {
      "name": "HCV RNA Viral Load",
      "alternateName": "HCV RNA",
      "direction": "up",
      "category": "hepatic",
      "comparison": "HCV-infected patients vs uninfected (detectable vs undetectable)",
      "symptoms": "",
      "reference": {
        "citation": "Dibba et al. 2018",
        "doi": "10.3390/diseases6020031"
      }
    }
  ]
}