{
  "slug": "chronic-kidney-disease",
  "id": "chronic-kidney-disease-biomarkers",
  "condition": {
    "name": "Chronic Kidney Disease",
    "shortName": "Chronic Kidney Disease",
    "alternateNames": []
  },
  "page": {
    "title": "Chronic Kidney Disease Biomarker Atlas | Blood Tests & Molecular Alterations",
    "breadcrumbName": "Chronic Kidney Disease Biomarkers",
    "description": "Searchable atlas of Chronic Kidney Disease biomarkers, from peer-reviewed literature comparing patient levels vs. healthy controls.",
    "keywords": [
      "Chronic Kidney Disease biomarkers",
      "Chronic Kidney Disease blood tests",
      "biomarker atlas",
      "biomarker database"
    ],
    "canonical": "https://research.opensourcemed.info/chronic-kidney-disease-biomarkers.html",
    "hero": "Molecular alterations reported in Chronic Kidney Disease compared to healthy controls, from peer-reviewed literature.",
    "dateModified": "2026-07-03"
  },
  "categories": {
    "renal": "Renal"
  },
  "filters": [
    "renal"
  ],
  "markers": [
    {
      "name": "Cystatin C",
      "alternateName": "Cystatin C",
      "direction": "up",
      "category": "renal",
      "comparison": "higher CV/CKD risk vs lower-risk individuals",
      "symptoms": "",
      "reference": {
        "citation": "Taglieri et al. 2009",
        "doi": "10.1373/clinchem.2009.128397"
      }
    },
    {
      "name": "eGFR",
      "alternateName": "eGFR",
      "direction": "down",
      "category": "renal",
      "comparison": "CKD vs healthy reference range",
      "symptoms": "",
      "reference": {
        "citation": "Li et al. 2024",
        "doi": "10.3389/fendo.2024.1329256"
      }
    },
    {
      "name": "Parathyroid Hormone",
      "alternateName": "Parathyroid Hormone",
      "direction": "up",
      "category": "renal",
      "comparison": "CKD (secondary hyperparathyroidism) vs normal",
      "symptoms": "",
      "reference": {
        "citation": "Jamal et al. 2013",
        "doi": "10.1016/j.jocd.2012.11.012"
      }
    },
    {
      "name": "Serum Creatinine",
      "alternateName": "Serum Creatinine",
      "direction": "up",
      "category": "renal",
      "comparison": "CKD/reduced renal function vs healthy",
      "symptoms": "",
      "reference": {
        "citation": "Benoit et al. 2020",
        "doi": "10.1080/14737159.2020.1768849"
      }
    },
    {
      "name": "Serum Phosphate",
      "alternateName": "Serum Phosphate",
      "direction": "up",
      "category": "renal",
      "comparison": "CKD vs normal",
      "symptoms": "",
      "reference": {
        "citation": "Petkovich et al. 2011",
        "doi": "10.1097/MNH.0b013e3283477a7b"
      }
    },
    {
      "name": "Urinary Albumin-Creatinine Ratio",
      "alternateName": "Urinary Albumin-Creatinine Ratio",
      "direction": "up",
      "category": "renal",
      "comparison": "CKD vs physiological/normal levels",
      "symptoms": "",
      "reference": {
        "citation": "Ruilope et al. 2023",
        "doi": "10.1093/eurheartj/ehac683"
      }
    }
  ]
}